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Literature DB >> 7611887

Enhancement by TNF-alpha of reactivation and replication of latent herpes simplex virus from trigeminal ganglia of mice.

Abstract

The influence of tumor-necrosis-factor-alpha (TNF-alpha), granulocyte-macrophage colony-stimulating factor (GM-CSF), interleukine-1 (IL-1) and IL-3 on the in vitro reactivation frequency and replication rate of trigeminal ganglia of mice latently infected with herpes simplex virus (HSV) strain KOS was studied. It could be demonstrated that TNF-alpha and possibility GM-CSF, but not IL-1 and IL-3, enhanced the reactivation frequency and replication of HSV. Interferon alpha/beta (IFN alpha/beta) prevented reactivation and replication.

Entities: Disease Gene Species

Mesh：

Substances：

Year: 1995 PMID： 7611887 DOI： 10.1007/BF01315409

Source DB: PubMed Journal: Arch Virol ISSN： 0304-8608 Impact factor: 2.574

18 in total

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Journal: J Virol Date: 1988-02 Impact factor: 5.103

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Journal: Arch Virol Date: 1992 Impact factor: 2.574

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Journal: Arch Virol Date: 1988 Impact factor: 2.574

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Journal: Arch Virol Date: 1990 Impact factor: 2.574

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Authors: G B Clements; P G Kennedy
Journal: Brain Date: 1989-10 Impact factor: 13.501

1. Use of differential display reverse transcription-PCR to reveal cellular changes during stimuli that result in herpes simplex virus type 1 reactivation from latency: upregulation of immediate-early cellular response genes TIS7, interferon, and interferon regulatory factor-1.

Authors: R Tal-Singer; W Podrzucki; T M Lasner; A Skokotas; J J Leary; N W Fraser; S L Berger
Journal: J Virol Date: 1998-02 Impact factor: 5.103

2. Role for gamma interferon in control of herpes simplex virus type 1 reactivation.

Authors: E Cantin; B Tanamachi; H Openshaw
Journal: J Virol Date: 1999-04 Impact factor: 5.103

3. Alzheimer's Disease: APP, Gamma Secretase, APOE, CLU, CR1, PICALM, ABCA7, BIN1, CD2AP, CD33, EPHA1, and MS4A2, and Their Relationships with Herpes Simplex, C. Pneumoniae, Other Suspect Pathogens, and the Immune System.

Authors: Chris Carter
Journal: Int J Alzheimers Dis Date: 2011-12-29

4. Reactivation of herpes simplex virus type 1 in the mouse trigeminal ganglion: an in vivo study of virus antigen and cytokines.

Authors: C Shimeld; D L Easty; T J Hill
Journal: J Virol Date: 1999-03 Impact factor: 5.103

4 in total