Literature DB >> 33552036

Antiproliferative Sorbicillinoids From the Deep-Sea-Derived Penicillium allii-sativi.

Chun-Lan Xie1,2, Duo Zhang1, Ting Lin1, Zhi-Hui He2, Qing-Xiang Yan2, Qi Cai1, Xiao-Kun Zhang1, Xian-Wen Yang2, Hai-Feng Chen1.   

Abstract

Two new (1-2) and three known (3-5) sorbicillinoids were isolated from the deep-sea-derived fungus Penicillium allii-sativi MCCC 3A00580. Compounds 1 and 2, named sorbicatechols C and D, were two new hybrid dihydrosorbillinoids. Their structures were established mainly by spectroscopic analyses and electronic circular dichroism (ECD) calculations. All five isolates were tested for antiproliferative activities against four tumor cell lines of MCF-7, HT-29, HuH-7, and LNCap. Compounds 2 and 5 inhibited HT-29 cells in a good dose-dependent manner. Mechanism investigation uncovered that they could significantly induce cell cycle G2-M phase arresting by increasing the protein levels of p-H3 and cyclin B1.
Copyright © 2021 Xie, Zhang, Lin, He, Yan, Cai, Zhang, Yang and Chen.

Entities:  

Keywords:  cell cycle; cytotoxicities; deep-sea; fungi; sorbicillinoids

Year:  2021        PMID： 33552036      PMCID： PMC7858254          DOI： 10.3389/fmicb.2020.636948

Source DB:  PubMed          Journal:  Front Microbiol        ISSN： 1664-302X            Impact factor:   5.640


  14 in total

1.  Nesteretal A, A Novel Class of Cage-Like Polyketide from Marine-Derived Actinomycete Nesterenkonia halobia.

Authors:  Chun-Lan Xie; Renzhi Chen; Sihan Yang; Jin-Mei Xia; Gai-Yun Zhang; Chao-Hong Chen; Yandong Zhang; Xian-Wen Yang
Journal:  Org Lett       Date:  2019-08-19       Impact factor: 6.005

2.  Spirograterpene A, a Tetracyclic Spiro-Diterpene with a Fused 5/5/5/5 Ring System from the Deep-Sea-Derived Fungus Penicillium granulatum MCCC 3A00475.

Authors:  Siwen Niu; Zuo-Wang Fan; Chun-Lan Xie; Qingmei Liu; Zhu-Hua Luo; Guangming Liu; Xian-Wen Yang
Journal:  J Nat Prod       Date:  2017-07-10       Impact factor: 4.050

Review 3.  The sorbicillinoid family of natural products: isolation, biosynthesis, and synthetic studies.

Authors:  Andrew M Harned; Kelly A Volp
Journal:  Nat Prod Rep       Date:  2011-09-16       Impact factor: 13.423

Review 4.  Cell cycle control and cancer.

Authors:  L H Hartwell; M B Kastan
Journal:  Science       Date:  1994-12-16       Impact factor: 47.728

5.  Strepsesquitriol, a rearranged zizaane-type sesquiterpenoid from the deep-sea-derived actinomycete Streptomyces sp. SCSIO 10355.

Authors:  Xian-Wen Yang; Kun Peng; Zhong Liu; Gai-Yun Zhang; Jie Li; Ning Wang; Andre Steinmetz; Yonghong Liu
Journal:  J Nat Prod       Date:  2013-12-11       Impact factor: 4.050

6.  Botryotins A-H, Tetracyclic Diterpenoids Representing Three Carbon Skeletons from a Deep-Sea-Derived Botryotinia fuckeliana.

Authors:  Siwen Niu; Chun-Lan Xie; Jin-Mei Xia; Qing-Mei Liu; Guizhen Peng; Guang-Ming Liu; Xian-Wen Yang
Journal:  Org Lett       Date:  2019-12-27       Impact factor: 6.005

7.  Cell cycle-dependent regulation of the cyclin B1 promoter.

Authors:  A Hwang; A Maity; W G McKenna; R J Muschel
Journal:  J Biol Chem       Date:  1995-11-24       Impact factor: 5.157

8.  Oxidative dearomatisation: the key step of sorbicillinoid biosynthesis†Electronic supplementary information (ESI) available: Containing all experimental details. See DOI: 10.1039/c3sc52911hClick here for additional data file.

Authors:  Ahmed Al Fahad; Amira Abood; Katja M Fisch; Anna Osipow; Jack Davison; Marija Avramović; Craig P Butts; Jörn Piel; Thomas J Simpson; Russell J Cox
Journal:  Chem Sci       Date:  2013-11-26       Impact factor: 9.825

9.  Sorbicillinoids From the Fungus Ustilaginoidea virens and Their Phytotoxic, Cytotoxic, and Antimicrobial Activities.

Authors:  Jiajia Meng; Gan Gu; Pengqin Dang; Xuping Zhang; Weixuan Wang; Jungui Dai; Yang Liu; Daowan Lai; Ligang Zhou
Journal:  Front Chem       Date:  2019-06-12       Impact factor: 5.221

Review 10.  Sorbicillinoids from Fungi and Their Bioactivities.

Authors:  Jiajia Meng; Xiaohan Wang; Dan Xu; Xiaoxiang Fu; Xuping Zhang; Daowan Lai; Ligang Zhou; Guozhen Zhang
Journal:  Molecules       Date:  2016-06-01       Impact factor: 4.411
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  3 in total

1.  Sorbicillinoid Derivatives with the Radical Scavenging Activities from the Marine-Derived Fungus Acremonium chrysogenum C10.

Authors:  Chengbao Duan; Shiyuan Wang; Ruiyun Huo; Erwei Li; Min Wang; Jinwei Ren; Yuanyuan Pan; Ling Liu; Gang Liu
Journal:  J Fungi (Basel)       Date:  2022-05-20

2.  Anti-Food Allergic Compounds from Penicillium griseofulvum MCCC 3A00225, a Deep-Sea-Derived Fungus.

Authors:  Cui-Ping Xing; Dan Chen; Chun-Lan Xie; Qingmei Liu; Tian-Hua Zhong; Zongze Shao; Guangming Liu; Lian-Zhong Luo; Xian-Wen Yang
Journal:  Mar Drugs       Date:  2021-04-16       Impact factor: 5.118

Review 3.  Recent Advances in Sorbicillinoids from Fungi and Their Bioactivities (Covering 2016-2021).

Authors:  Xuwen Hou; Xuping Zhang; Mengyao Xue; Zhitong Zhao; Huizhen Zhang; Dan Xu; Daowan Lai; Ligang Zhou
Journal:  J Fungi (Basel)       Date:  2022-01-07
  3 in total

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