| Literature DB >> 24490634 |
Xian-Wen Yang1, Kun Peng, Zhong Liu, Gai-Yun Zhang, Jie Li, Ning Wang, Andre Steinmetz, Yonghong Liu.
Abstract
Strepsesquitriol, a new caged sesquiterpene, was isolated from Streptomyces sp. SCSIO 10355. Its absolute structure was established as (1R,2R,4S,5S,8S,10S)-4,9,9,10-tetramethyl-2,5,10-trihydroxytricyclo[6.2.1.0(1,5)]undecane by NMR analysis and a theoretical optical rotation derived from quantum-chemical calculations. It showed moderate inhibitory activity against lipopolysaccharide-induced TNFα production in RAW264.7 macrophages.Entities:
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Year: 2013 PMID: 24490634 DOI: 10.1021/np400923c
Source DB: PubMed Journal: J Nat Prod ISSN: 0163-3864 Impact factor: 4.050