Literature DB >> 33516221

Application of ultrasound-guided intranodal lymphangiography and embolisation in cancer patients with postoperative lymphatic leakage.

Xingwei Sun1, Feng Zhou2, Mingqing Zhang1, Xuming Bai1, Qiang Yuan1, Liang Ma3, Yong Jin4.   

Abstract

BACKGROUND: Traumatic lymphatic leakage is a rare but potentially life-threatening complication. The purpose of this study was to introduce ultrasound-guided intranodal lymphangiography and embolisation techniques for postoperative lymphatic leakage in patients with cancer.
METHODS: From January 2018 through June 2020, seven cancer patients (three males, four females, aged 59-75 years [mean 67.57 ± 6.11 years]) developed lymphatic leakage after abdominal or pelvic surgery, with drainage volumes ranging from 550 to 1200 mL per day. The procedure and follow-up of ultrasound-guided intranodal lymphangiography and embolisation were recorded. This study retrospectively analysed the technical success rate, operative time, length of hospital stay, clinical efficacy, and complications.
RESULTS: The operation was technically successful in all patients. Angiography revealed leakage, and embolisation was performed in all seven patients (7/7, 100%). The operative time of angiography and embolisation was 41 to 68 min, with an average time of 53.29 ± 10.27 min. The mean length of stay was 3.51 ± 1.13 days. Lymph node embolisation was clinically successful in five patients (5/7, 71.43%), who had a significant reduction in or disappearance of chylous ascites. The other two patients received surgical treatment 2 weeks later due to poor results after embolisation. All patients were followed for 2 weeks. No serious complications or only minor complications were found in all the patients.
CONCLUSIONS: Ultrasound-guided intranodal lymphangiography and embolisation were well tolerated by the patients, who experienced a low incidence of complications. Early intervention is recommended for cancer patients with postoperative lymphatic leakage.

Entities:  

Keywords:  Lymphangiography; Lymphatic leakage; Ultrasound-guided

Mesh:

Year:  2021        PMID: 33516221      PMCID: PMC7847140          DOI: 10.1186/s12957-021-02144-2

Source DB:  PubMed          Journal:  World J Surg Oncol        ISSN: 1477-7819            Impact factor:   2.754


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  3 in total

Review 1.  Lymphatic Interventions in the Cancer Patient.

Authors:  Eslam Wassal Youssef; Ahmed Aly; Akshaar Brahmbhatt; Amgad Moussa; Ernesto Santos
Journal:  Curr Oncol Rep       Date:  2022-05-31       Impact factor: 5.945

Review 2.  Lymph Nodes as Anti-Tumor Immunotherapeutic Tools: Intranodal-Tumor-Specific Antigen-Pulsed Dendritic Cell Vaccine Immunotherapy.

Authors:  Takashi Morisaki; Takafumi Morisaki; Makoto Kubo; Shinji Morisaki; Yusuke Nakamura; Hideya Onishi
Journal:  Cancers (Basel)       Date:  2022-05-15       Impact factor: 6.575

Review 3.  The Delivery of mRNA Vaccines for Therapeutics.

Authors:  Jiao Wei; Ai-Min Hui
Journal:  Life (Basel)       Date:  2022-08-17
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