Literature DB >> 33515323

Infection and periprosthetic fracture are the leading causes of failure after aseptic revision total knee arthroplasty.

Juliette A Meyer1, Mark Zhu1, Alana Cavadino1, Brendan Coleman2, Jacob T Munro3, Simon W Young4,5.   

Abstract

AIM: The purpose of this study was to clarify the medium to long term survival of aseptic revision total knee arthroplasty (RTKAs) and identify the common modes of failure following RTKAs.
MATERIALS AND METHODS: A multi-center, retrospective study included all aseptic RTKAs performed at three tertiary referral hospitals between 2003 and 2016. Patients were excluded if the revision was for prosthetic joint infection (PJI) or they had previously undergone revision surgery. Minor revisions not involving the tibial or femoral components were also excluded. Demographics, surgical data and post-operative outcomes were recorded and analyzed. Survival analysis was performed and the reasons for revision failure identified.
RESULTS: Of 235 aseptic RTKAs identified, 14.8% underwent re-revision at mean follow-up of 8.3 years. Survivorship of RTKA was 93% at 2 years and 83% at 8 years. Average age at revision was 72.9 years (range 53-91.5). The most common reasons for failure following RTKA were periprosthetic joint infection (PJI) (40%), periprosthetic fracture (25.7%) and aseptic loosening (14.3%). Of those whose RTKA failed, the average survival was 3.33 years (8 days-11.4 years). No demographic or surgical factors were found to influence RTKA survival on univariate or multivariate analysis.
CONCLUSION: PJI and periprosthetic fracture are the leading causes of re-revision surgery following aseptic revision TKA. Efforts to improve outcomes of aseptic revision TKA should focus on these areas, particularly prevention of PJI.
© 2021. The Author(s), under exclusive licence to Springer-Verlag GmbH, DE part of Springer Nature.

Entities:  

Keywords:  Periprosthetic fracture; Periprosthetic joint infection; Revision total knee arthroplasty

Year:  2021        PMID: 33515323     DOI: 10.1007/s00402-020-03698-8

Source DB:  PubMed          Journal:  Arch Orthop Trauma Surg        ISSN: 0936-8051            Impact factor:   3.067


  31 in total

1.  Increased long-term survival of posterior cruciate-retaining versus posterior cruciate-stabilizing total knee replacements.

Authors:  Matthew P Abdel; Mark E Morrey; Matthew R Jensen; Bernard F Morrey
Journal:  J Bone Joint Surg Am       Date:  2011-11-16       Impact factor: 5.284

2.  Projections of primary and revision hip and knee arthroplasty in the United States from 2005 to 2030.

Authors:  Steven Kurtz; Kevin Ong; Edmund Lau; Fionna Mowat; Michael Halpern
Journal:  J Bone Joint Surg Am       Date:  2007-04       Impact factor: 5.284

3.  Why do revision knee arthroplasties fail?

Authors:  Juan Suarez; William Griffin; Bryan Springer; Thomas Fehring; J Bohannon Mason; Susan Odum
Journal:  J Arthroplasty       Date:  2008-06-05       Impact factor: 4.757

Review 4.  Revision rates after total joint replacement: cumulative results from worldwide joint register datasets.

Authors:  G Labek; M Thaler; W Janda; M Agreiter; B Stöckl
Journal:  J Bone Joint Surg Br       Date:  2011-03

5.  Total knee arthroplasty volume, utilization, and outcomes among Medicare beneficiaries, 1991-2010.

Authors:  Peter Cram; Xin Lu; Stephen L Kates; Jasvinder A Singh; Yue Li; Brian R Wolf
Journal:  JAMA       Date:  2012-09-26       Impact factor: 56.272

6.  The 2018 Definition of Periprosthetic Hip and Knee Infection: An Evidence-Based and Validated Criteria.

Authors:  Javad Parvizi; Timothy L Tan; Karan Goswami; Carlos Higuera; Craig Della Valle; Antonia F Chen; Noam Shohat
Journal:  J Arthroplasty       Date:  2018-02-26       Impact factor: 4.757

7.  Predicting the Burden of Revision Knee Arthroplasty: Simulation of a 20-Year Horizon.

Authors:  Richard E Guerrero-Ludueña; Mercè Comas; Mireia Espallargues; Moisès Coll; Miquel Pons; Santiago Sabatés; Alejandro Allepuz; Xavier Castells
Journal:  Value Health       Date:  2016-04-23       Impact factor: 5.725

8.  Why are total knee arthroplasties failing today--has anything changed after 10 years?

Authors:  Peter F Sharkey; Paul M Lichstein; Chao Shen; Anthony T Tokarski; Javad Parvizi
Journal:  J Arthroplasty       Date:  2014-07-05       Impact factor: 4.757

9.  Future young patient demand for primary and revision joint replacement: national projections from 2010 to 2030.

Authors:  Steven M Kurtz; Edmund Lau; Kevin Ong; Ke Zhao; Michael Kelly; Kevin J Bozic
Journal:  Clin Orthop Relat Res       Date:  2009-04-10       Impact factor: 4.176

10.  New Zealand Joint Registry data underestimates the rate of prosthetic joint infection.

Authors:  Mark Zhu; Saiprasad Ravi; Chris Frampton; Chris Luey; Simon Young
Journal:  Acta Orthop       Date:  2016-06-27       Impact factor: 3.717

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  5 in total

Review 1.  Prevalence, interpretation, and management of unexpected positive cultures in revision TKA: a systematic review.

Authors:  Johannes Kloos; Koen Vander Linden; Stijn Vermote; Pieter Berger; Hilde Vandenneucker
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2022-01-15       Impact factor: 4.342

2.  Comparison of dynamic and static spacers for the treatment of infections following total knee replacement: a systematic review and meta-analysis.

Authors:  Jiasheng Tao; Zijian Yan; Bin Pu; Ming Chen; Xiaorong Hu; Hang Dong
Journal:  J Orthop Surg Res       Date:  2022-07-15       Impact factor: 2.677

3.  Plasma fibrinogen: a sensitive biomarker for the screening of periprosthetic joint infection in patients undergoing re-revision arthroplasty.

Authors:  Hong Xu; Li Liu; Jinwei Xie; Qiang Huang; Yahao Lai; Zongke Zhou
Journal:  BMC Musculoskelet Disord       Date:  2022-06-01       Impact factor: 2.562

4.  Preliminary Study on Immediate Postoperative CT Images and Values of the Modular Polyetheretherketone Based Total Knee Arthroplasty: An Observational First-in-Human Trial.

Authors:  Zhengyu Cai; Xinhua Qu; Yaochao Zhao; Zhiguo Yuan; Liangjun Zheng; Teng Long; Qiuying Yao; Bing Yue; You Wang
Journal:  Front Surg       Date:  2022-02-14

5.  A Decision Support Framework for Periprosthetic Joint Infection Treatment: A Cost-Effectiveness Analysis Using Two Modeling Approaches.

Authors:  Vasiliy N Leonenko; Yulia E Kaliberda; Yulia V Muravyova; Vasiliy A Artyukh
Journal:  J Pers Med       Date:  2022-07-26
  5 in total

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