| Literature DB >> 33511108 |
Xinming Gu1, Xiaolin Sun1, Yue Sun1, Jia Wang1, Yiping Liu1, Kaixuan Yu1, Yao Wang1, Yanmin Zhou1.
Abstract
In recent years, <span class="Chemical">polyetheretherketone (<span class="Chemical">PEEK) has been increasingly employed as an implant material in clinical applications. Although PEEK is biocompatible, chemically stable, and radiolucent and has an elastic modulus similar to that of natural bone, it suffers from poor integration with surrounding bone tissue after implantation. To improve the bioactivity of PEEK, numerous strategies for functionalizing the PEEK surface and changing the PEEK structure have been proposed. Inspired by the components, structure, and function of bone tissue, this review discusses strategies to enhance the biocompatibility of PEEK implants and provides direction for fabricating multifunctional implants in the future.Entities:
Keywords: bioactivity; implants; osseointegration; polyetheretherketone; surface modification
Year: 2021 PMID: 33511108 PMCID: PMC7835420 DOI: 10.3389/fbioe.2020.631616
Source DB: PubMed Journal: Front Bioeng Biotechnol ISSN: 2296-4185