Literature DB >> 36105563

On the mechanical aspect of additive manufactured polyether-ether-ketone scaffold for repair of large bone defects.

Seyed Ataollah Naghavi1, Changning Sun2, Mahbubeh Hejazi3, Maryam Tamaddon1, Jibao Zheng2, Leilei Wang2, Chenrui Zhang2, Swastina Nath Varma1, Dichen Li2, Mehran Moazen3, Ling Wang2, Chaozong Liu1.   

Abstract

Polyether-ether-ketone (PEEK) is widely used in producing prosthesis and have gained great attention for repair of large bone defect in recent years with the development of additive manufacturing. This is due to its excellent biocompatibility, good heat and chemical stability and similar mechanical properties which mimics natural bone. In this study, three replicates of rectilinear scaffolds were designed for compression, tension, three-point bending and torsion test with unit cell size of 0.8 mm, a pore size of 0.4 mm, strut thickness of 0.4 mm and nominal porosity of 50%. Stress-strain graphs were developed from experimental and finite element analysis models. Experimental Young's modulus and yield strength of the scaffolds were measured from the slop of the stress-strain graph to be 395 and 19.50 MPa respectively for compression, 427 and 6.96 MPa respectively for tension, 257 and 25.30 MPa respectively for three-point bending and 231 and 12.83 MPa respectively for torsion test. The finite element model was found to be in good agreement with the experimental results. Ductile fracture of the struct subjected to tensile strain was the main failure mode of the PEEK scaffold, which stems from the low crystallinity of additive manufacturing PEEK. The mechanical properties of porous PEEK are close to those of cancellous bone and thus are expected to be used in additive manufacturing PEEK bone implants in the future, but the lower yield strength poses a design challenge.

Entities:  

Keywords:  PEEK scaffold; additive manufacturing; bone scaffold; finite element analysis; lattice structure; mechanical behaviour

Year:  2022        PMID: 36105563      PMCID: PMC9465988          DOI: 10.12336/biomatertransl.2022.02.006

Source DB:  PubMed          Journal:  Biomater Transl        ISSN: 2096-112X


  19 in total

Review 1.  Functionally graded materials for orthopedic applications - an update on design and manufacturing.

Authors:  Antonella Sola; Devis Bellucci; Valeria Cannillo
Journal:  Biotechnol Adv       Date:  2016-01-03       Impact factor: 14.227

2.  Custom design and biomechanical analysis of 3D-printed PEEK rib prostheses.

Authors:  Jianfeng Kang; Ling Wang; Chuncheng Yang; Lei Wang; Cao Yi; Jiankang He; Dichen Li
Journal:  Biomech Model Mechanobiol       Date:  2018-05-05

3.  Biomechanical response of a novel intervertebral disc prosthesis using functionally graded polymers: A finite element study.

Authors:  Qifeng Jiang; Fahmi Zaïri; Caroline Fréderix; Zhu Yan; Amil Derrouiche; Zhengwei Qu; Xiaobing Liu; Fahed Zaïri
Journal:  J Mech Behav Biomed Mater       Date:  2019-02-20

4.  Facile Surface Modification Method for Synergistically Enhancing the Biocompatibility and Bioactivity of Poly(ether ether ketone) That Induced Osteodifferentiation.

Authors:  Yuchen Zhu; Zhe Cao; Ying Peng; Liqiu Hu; Tankut Guney; Bin Tang
Journal:  ACS Appl Mater Interfaces       Date:  2019-07-23       Impact factor: 9.229

5.  3D-printed PEEK implant for mandibular defects repair - a new method.

Authors:  Jianfeng Kang; Jie Zhang; Jibao Zheng; Ling Wang; Dichen Li; Shuguang Liu
Journal:  J Mech Behav Biomed Mater       Date:  2021-01-21

6.  Mechanical characterization and numerical simulation of polyether-ether-ketone (PEEK) cranial implants.

Authors:  F El Halabi; J F Rodriguez; L Rebolledo; E Hurtós; M Doblaré
Journal:  J Mech Behav Biomed Mater       Date:  2011-06-06

7.  Three-dimensional printed polycaprolactone-microcrystalline cellulose scaffolds.

Authors:  Maria Elena Alemán-Domínguez; Elena Giusto; Zaida Ortega; Maryam Tamaddon; Antonio Nizardo Benítez; Chaozong Liu
Journal:  J Biomed Mater Res B Appl Biomater       Date:  2018-05-02       Impact factor: 3.368

8.  Strategy for Controlling the Properties of Bioactive Poly-Ether-Ether-Ketone/Hydroxyapatite Composites for Bone Tissue Engineering Scaffolds.

Authors:  Gaoyan Zhong; Mohammad Vaezi; Xinliang Mei; Ping Liu; Shoufeng Yang
Journal:  ACS Omega       Date:  2019-11-05

Review 9.  Fused Filament Fabrication of PEEK: A Review of Process-Structure-Property Relationships.

Authors:  Ali Reza Zanjanijam; Ian Major; John G Lyons; Ugo Lafont; Declan M Devine
Journal:  Polymers (Basel)       Date:  2020-07-27       Impact factor: 4.329

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