Literature DB >> 33505810

Testicular Torsion in a Rare Case of Prostatic Spindle Cell Rhabdomyosarcoma.

Subramaniyan Ashuvanth1, Ramanan Sinduja1, Chellappa Vijayakumar1, Uday Kumbhar1, Pampa C Toi2.   

Abstract

Spindle cell sarcoma of the prostate is a rare variant of rhabdomyosarcoma (RMS), with the clinical experience limited to a handful of cases in the literature. We report a rare case of spindle cell rhabdomyosarcoma (SC-RMS) who presented to us with testicular torsion features. A 20-year-old male presented initially with lower urinary tract symptoms and features of epidiymo-orchitis, which was managed conservatively. He later presented with features suggestive of testicular torsion and underwent orchidopexy. The patient developed postoperative urinary retention. On per-rectal examination, there was gross prostatomegaly. He was evaluated with a trans-rectal biopsy and contrast-enhanced computed tomography (CECT). Subsequently, he was found to have metastatic prostatic SC-RMS, which is a rare disease. He was started on chemotherapy and radiotherapy. SC-RMS is a variant that has a comparatively favorable prognosis in children and an aggressive course in adults, as reported in the few cases so far. The treatment regimen is still evolving, and there is no consensus on the therapeutic approach. All these factors together result in the dismal outlook of patients diagnosed with this condition.
Copyright © 2020, Ashuvanth et al.

Entities:  

Keywords:  epidiymo-orchitis; prostatomegaly; rhabdomyosarcoma; spindle cell; testicular torsion

Year:  2020        PMID: 33505810      PMCID: PMC7822391          DOI: 10.7759/cureus.12238

Source DB:  PubMed          Journal:  Cureus        ISSN: 2168-8184


  7 in total

1.  Spindle cell rhabdomyosarcoma. A prognostically favorable variant of rhabdomyosarcoma.

Authors:  A O Cavazzana; D Schmidt; V Ninfo; D Harms; M Tollot; M Carli; J Treuner; R Betto; G Salviati
Journal:  Am J Surg Pathol       Date:  1992-03       Impact factor: 6.394

2.  Spindle cell rhabdomyosarcoma in adults: clinicopathological and immunohistochemical analysis of seven new cases.

Authors:  Thomas Mentzel; Cornelius Kuhnen
Journal:  Virchows Arch       Date:  2006-09-30       Impact factor: 4.064

3.  The World Health Organization Classification of Skeletal Muscle Tumors in Pediatric Rhabdomyosarcoma: A Report From the Children's Oncology Group.

Authors:  Erin R Rudzinski; James R Anderson; Douglas S Hawkins; Stephen X Skapek; David M Parham; Lisa A Teot
Journal:  Arch Pathol Lab Med       Date:  2015-05-19       Impact factor: 5.534

4.  The incidence rate and characteristics in patients with testicular torsion: a nationwide, population-based study.

Authors:  Wei-Yi Huang; Yu-Fen Chen; Hong-Chiang Chang; Teng-Kai Yang; Ju-Ton Hsieh; Kuo-How Huang
Journal:  Acta Paediatr       Date:  2013-05-13       Impact factor: 2.299

5.  The Intergroup Rhabdomyosarcoma Study-II.

Authors:  H M Maurer; E A Gehan; M Beltangady; W Crist; P S Dickman; S S Donaldson; C Fryer; D Hammond; D M Hays; J Herrmann
Journal:  Cancer       Date:  1993-03-01       Impact factor: 6.860

6.  Classification of rhabdomyosarcomas and related sarcomas. Pathologic aspects and proposal for a new classification--an Intergroup Rhabdomyosarcoma Study.

Authors:  W A Newton; E A Gehan; B L Webber; H B Marsden; A J van Unnik; A B Hamoudi; M G Tsokos; H Shimada; D Harms; D Schmidt
Journal:  Cancer       Date:  1995-09-15       Impact factor: 6.860

Review 7.  Spindle cell rhabdomyosarcoma: a brief diagnostic review and differential diagnosis.

Authors:  Sarah Jayne Carroll; Laurentia Nodit
Journal:  Arch Pathol Lab Med       Date:  2013-08       Impact factor: 5.534

  7 in total

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