Literature DB >> 33499955

Faecal inoculations alter the gastrointestinal microbiome and allow dietary expansion in a wild specialist herbivore, the koala.

Michaela D J Blyton1, Rochelle M Soo2, Desley Whisson3, Karen J Marsh4, Jack Pascoe5, Mark Le Pla5, William Foley4, Philip Hugenholtz2, Ben D Moore6.   

Abstract

BACKGROUND: Differences between individuals in their gastrointestinal microbiomes can lead to variation in their ability to persist on particular diets. Koalas are dietary specialists, feeding almost exclusively on Eucalyptus foliage but many individuals will not feed on particular Eucalyptus species that are adequate food for other individuals, even when facing starvation. We undertook a faecal inoculation experiment to test whether a koala's gastrointestinal (GI) microbiome influences their diet. Wild-caught koalas that initially fed on the preferred manna gum (Eucalyptus viminalis) were brought into captivity and orally inoculated with encapsulated material derived from faeces from koalas feeding on either the less preferred messmate (E. obliqua; treatment) or manna gum (control).
RESULTS: The gastrointestinal microbiomes of wild koalas feeding primarily on manna gum were distinct from those feeding primarily on messmate. We found that the gastrointestinal microbiomes of koalas were unresponsive to dietary changes because the control koalas' GI microbiomes did not change even when the nocturnal koalas were fed exclusively on messmate overnight. We showed that faecal inoculations can assist the GI microbiomes of koalas to change as the treatment koalas' GI microbiomes became more similar to those of wild koalas feeding on messmate. There was no overall difference between the control and treatment koalas in the quantity of messmate they consumed. However, the greater the change in the koalas' GI microbiomes, the more messmate they consumed after the inoculations had established.
CONCLUSIONS: The results suggest that dietary changes can only lead to changes in the GI microbiomes of koalas if the appropriate microbial species are present, and/or that the koala gastrointestinal microbiome influences diet selection.

Entities:  

Keywords:  Diet; E. obliqua; E. viminalis; Eucalyptus; Faecal transplant; Gastrointestinal; Koala; Microbiome

Year:  2019        PMID: 33499955      PMCID: PMC7803123          DOI: 10.1186/s42523-019-0008-0

Source DB:  PubMed          Journal:  Anim Microbiome        ISSN: 2524-4671


  45 in total

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2.  Formation of a clear zone on tannin-treated brain heart infusion agar by a Streptococcus sp. isolated from feces of koalas.

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4.  Antiherbivore chemistry of Eucalyptus-cues and deterrents for marsupial folivores.

Authors:  Ben D Moore; Ian R Wallis; Jesús Palá-Paul; Joseph J Brophy; Richard H Willis; William J Foley
Journal:  J Chem Ecol       Date:  2004-09       Impact factor: 2.626

5.  Tree use by koalas in a chemically complex landscape.

Authors:  Ben D Moore; William J Foley
Journal:  Nature       Date:  2005-05-26       Impact factor: 49.962

6.  Transmission modes of the mammalian gut microbiota.

Authors:  Andrew H Moeller; Taichi A Suzuki; Megan Phifer-Rixey; Michael W Nachman
Journal:  Science       Date:  2018-10-26       Impact factor: 47.728

7.  Diet rapidly and reproducibly alters the human gut microbiome.

Authors:  Lawrence A David; Corinne F Maurice; Rachel N Carmody; David B Gootenberg; Julie E Button; Benjamin E Wolfe; Alisha V Ling; A Sloan Devlin; Yug Varma; Michael A Fischbach; Sudha B Biddinger; Rachel J Dutton; Peter J Turnbaugh
Journal:  Nature       Date:  2013-12-11       Impact factor: 49.962

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Journal:  Nucleic Acids Res       Date:  2012-11-28       Impact factor: 16.971

Review 9.  Dietary effects on human gut microbiome diversity.

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Authors:  Jingjing Wang; Huang Tang; Chenhong Zhang; Yufeng Zhao; Muriel Derrien; Emilie Rocher; Johan E T van-Hylckama Vlieg; Katherine Strissel; Liping Zhao; Martin Obin; Jian Shen
Journal:  ISME J       Date:  2014-06-17       Impact factor: 10.302

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Authors:  Karen J Marsh; Michaela D J Blyton; William J Foley; Ben D Moore
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3.  Signatures of landscape and captivity in the gut microbiota of Southern Hairy-nosed Wombats (Lasiorhinus latifrons).

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6.  Wild and Captive Environments Drive the Convergence of Gut Microbiota and Impact Health in Threatened Equids.

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7.  How microbiomes can help inform conservation: landscape characterisation of gut microbiota helps shed light on additional population structure in a specialist folivore.

Authors:  B L Littleford-Colquhoun; L S Weyrich; K Hohwieler; R Cristescu; C H Frère
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