Literature DB >> 33499336

Risk Factors for Surgical Treatment of Endometrial Cancer Using Traditional and Laparoscopic Methods.

Sławomir M Januszek1, Barbara Wita-Popow1, Marta Kluz2, Magdalena Janowska1, Rafał Januszek3, Andrzej Wróbel4, Artur Rogowski5,6, Krzysztof P Malinowski7, Tomasz Zuzak1, Tomasz Kluz1,8.   

Abstract

Surgical treatment is the most important part of therapy for endometrial cancer. The aim of the study was to define factors having the most significant impact on surgical treatment of endometrial cancer when using traditional and laparoscopic methods. In the study, we evaluated 75 females who were treated for endometrial cancer via laparoscopic surgery in 2019 and used a historical control of 70 patients treated by laparotomy in 2011. The evaluated risk factors included the method of surgery, type of lymphadenectomy, patient's age, various obesity parameters, histological grading, cancer clinical staging, pelvic dimensions, previous abdominal surgeries, comorbidities, and number of deliveries. The duration of hospitalization, operation time, loss of hemoglobin, and procedure-related complications were used as parameters of perioperative outcomes. Multivariable linear regression analysis confirmed the following factors as being predictors of worse perioperative outcomes: laparotomy, abdominal obesity (waist circumstance and waist-to-hip ratio), range of lymphadenectomy, prior abdominal surgeries, and larger pelvic dimensions. Abdominal obesity is a significant risk factor in the treatment of endometrial cancer. Laparotomy continues to be utilized frequently in the management of endometrial cancer in Poland as well as elsewhere, and adopting a minimally invasive approach is likely to be beneficial for patient outcome.

Entities:  

Keywords:  abdominal obesity; endometrial cancer; perioperative outcomes; sentinel node procedure lymphadenectomy; surgical treatment; total laparoscopic hysterectomy

Year:  2021        PMID: 33499336      PMCID: PMC7865410          DOI: 10.3390/jcm10030429

Source DB:  PubMed          Journal:  J Clin Med        ISSN: 2077-0383            Impact factor:   4.241


  28 in total

1.  The impact of obesity on the 30-day morbidity and mortality after surgery for endometrial cancer.

Authors:  Haider Mahdi; Amelia M Jernigan; Qataralnada Aljebori; David Lockhart; Mehdi Moslemi-Kebria
Journal:  J Minim Invasive Gynecol       Date:  2014-07-24       Impact factor: 4.137

2.  Laparoscopic surgery for early endometrial cancer.

Authors:  Gitte Bennich; Martin Rudnicki; Pernille D Lassen
Journal:  Acta Obstet Gynecol Scand       Date:  2016-05-30       Impact factor: 3.636

3.  Comparison of minimally invasive surgery with laparotomic approach in the treatment of high risk endometrial cancer: A systematic review.

Authors:  G Scaletta; G Dinoi; V Capozzi; S Cianci; S Pelligra; R Ergasti; A Fagotti; G Scambia; F Fanfani
Journal:  Eur J Surg Oncol       Date:  2019-12-02       Impact factor: 4.424

4.  Total laparoscopic hysterectomy versus total abdominal hysterectomy for obese women with endometrial cancer.

Authors:  A Obermair; T P Manolitsas; Y Leung; I G Hammond; A J McCartney
Journal:  Int J Gynecol Cancer       Date:  2005 Mar-Apr       Impact factor: 3.437

5.  Quality of life after total laparoscopic hysterectomy versus total abdominal hysterectomy for stage I endometrial cancer (LACE): a randomised trial.

Authors:  Monika Janda; Val Gebski; Alison Brand; Russel Hogg; Thomas W Jobling; Russel Land; Tom Manolitsas; Anthony McCartney; Marcelo Nascimento; Deborah Neesham; James L Nicklin; Martin K Oehler; Geoff Otton; Lewis Perrin; Stuart Salfinger; Ian Hammond; Yee Leung; Tom Walsh; Peter Sykes; Hextan Ngan; Andrea Garrett; Michael Laney; Tong Yow Ng; Karfai Tam; Karen Chan; C David H Wrede; Selvan Pather; Bryony Simcock; Rhonda Farrell; Andreas Obermair
Journal:  Lancet Oncol       Date:  2010-07-16       Impact factor: 41.316

6.  Impact of Obesity on Surgical Treatment for Endometrial Cancer: A Multicenter Study Comparing Laparoscopy vs Open Surgery, with Propensity-Matched Analysis.

Authors:  Stefano Uccella; Matteo Bonzini; Stefano Palomba; Francesco Fanfani; Marcello Ceccaroni; Renato Seracchioli; Enrico Vizza; Annamaria Ferrero; Giovanni Roviglione; Paolo Casadio; Giacomo Corrado; Giovanni Scambia; Fabio Ghezzi
Journal:  J Minim Invasive Gynecol       Date:  2015-08-14       Impact factor: 4.137

7.  Feasibility and morbidity of total laparoscopic radical hysterectomy with or without pelvic limphadenectomy in obese women with stage I endometrial cancer.

Authors:  Antonio Pellegrino; Mauro Signorelli; Robert Fruscio; Annalisa Villa; Alessandro Buda; Pietro Beretta; Annalisa Garbi; Domenico Vitobello
Journal:  Arch Gynecol Obstet       Date:  2008-09-16       Impact factor: 2.344

8.  Impact of pelvic dimensions on anastomotic leak after anterior resection for patients with rectal cancer.

Authors:  Zhao-Liang Yu; Xuan-Hui Liu; Hua-Shan Liu; Jia Ke; Yi-Feng Zou; Wu-Teng Cao; Jian Xiao; Zhi-Yang Zhou; Ping Lan; Xiao-Jian Wu; Xian-Rui Wu
Journal:  Surg Endosc       Date:  2020-05-14       Impact factor: 4.584

9.  Laparoscopy versus laparotomy for surgical treatment of obese women with endometrial cancer: A cost-benefit comparative analysis.

Authors:  Vito Andrea Capozzi; Giulio Sozzi; Giulia Gambino; Alessandra Cianciolo; Matteo Riccò; Luciano Monfardini; Michela Gaiano; Vito Chiantera; Stefano Uccella; Roberto Berretta
Journal:  Mol Clin Oncol       Date:  2019-07-22

10.  Ten years of experience with endometrial cancer treatment in a single Brazilian institution: Patient characteristics and outcomes.

Authors:  Cristina Anton; Rodolpho Truffa Kleine; Eric Mayerhoff; Maria Del Pilar Esteves Diz; Daniela de Freitas; Heloisa de Andrade Carvalho; João Paulo Mancusi de Carvalho; Alexandre Silva E Silva; Maria Luiza Nogueira Dias Genta; André Lopes de Faria E Silva; Rafael Calil Salim; Andrea Aranha; Rossana Veronica Mendoza Lopez; Filomena Marino Carvalho; Edmund Chada Baracat; Jesus Paula Carvalho
Journal:  PLoS One       Date:  2020-03-05       Impact factor: 3.240

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