| Literature DB >> 33499336 |
Sławomir M Januszek1, Barbara Wita-Popow1, Marta Kluz2, Magdalena Janowska1, Rafał Januszek3, Andrzej Wróbel4, Artur Rogowski5,6, Krzysztof P Malinowski7, Tomasz Zuzak1, Tomasz Kluz1,8.
Abstract
Surgical treatment is the most important part of therapy for endometrial cancer. The aim of the study was to define factors having the most significant impact on surgical treatment of endometrial cancer when using traditional and laparoscopic methods. In the study, we evaluated 75 females who were treated for endometrial cancer via laparoscopic surgery in 2019 and used a historical control of 70 patients treated by laparotomy in 2011. The evaluated risk factors included the method of surgery, type of lymphadenectomy, patient's age, various obesity parameters, histological grading, cancer clinical staging, pelvic dimensions, previous abdominal surgeries, comorbidities, and number of deliveries. The duration of hospitalization, operation time, loss of hemoglobin, and procedure-related complications were used as parameters of perioperative outcomes. Multivariable linear regression analysis confirmed the following factors as being predictors of worse perioperative outcomes: laparotomy, abdominal obesity (waist circumstance and waist-to-hip ratio), range of lymphadenectomy, prior abdominal surgeries, and larger pelvic dimensions. Abdominal obesity is a significant risk factor in the treatment of endometrial cancer. Laparotomy continues to be utilized frequently in the management of endometrial cancer in Poland as well as elsewhere, and adopting a minimally invasive approach is likely to be beneficial for patient outcome.Entities:
Keywords: abdominal obesity; endometrial cancer; perioperative outcomes; sentinel node procedure lymphadenectomy; surgical treatment; total laparoscopic hysterectomy
Year: 2021 PMID: 33499336 PMCID: PMC7865410 DOI: 10.3390/jcm10030429
Source DB: PubMed Journal: J Clin Med ISSN: 2077-0383 Impact factor: 4.241