Literature DB >> 33489332

Surgical Treatment of Epiblepharon Effectively Alleviates Keratopathy but Not Astigmatism: A Case-Control Study Utilizing Vector Analysis in East Asian Children.

Shang-Te Ma1,2, Yao-Lin Liu2, Ching-Ju Hsieh3, Yo-Shen Chen4, Tzu-Hsun Tsai2.   

Abstract

PURPOSE: To identify an appropriate surgical indication of epiblepharon by comparing keratopathy and astigmatism outcomes after surgical and medical treatments for epiblepharon in Asian children.
METHODS: Children diagnosed with epiblepharon (n = 82, age 5.93 ± 2.76 years) with >6 months of follow-up were enrolled. The clinical presentations and cycloplegic refractive status at the baseline and 3 and 6 months after treatment were compared between surgical (91 eyes from 47 children) and nonsurgical (67 eyes from 35 children) groups. The refractive and keratometric astigmatism at each time point were evaluated with vector analysis methods. For Thibos and Horner's method, the astigmatic power vector was decomposed into horizontal and oblique meridians (J 0 and J 45). However, the treatment-induced astigmatism (TIA) vectors were calculated by Alpins' method and depicted by the AstigMATIC software.
RESULTS: In the surgical and nonsurgical groups, the baseline astigmatism magnitude was similar (2.22 ± 1.39 and 2.26 ± 1.46 D, p = 0.87). The rate of complete resolution of keratopathy at 6 months was 71.4% and 11.5%. The astigmatism magnitude in the surgical group differed among baseline and 3 months (2.25 ± 1.23 D) and 6 months postoperatively (1.97 ± 1.28 D) (p = 0.001). Power vector analyses confirmed a nuanced against-the-rule shift in the surgical group. This trend was especially observed in the subgroup of baseline astigmatism >2.0 D. However, the difference in the astigmatism magnitude between surgical and nonsurgical groups, even in highly astigmatic children, was not significant at 6 months.
CONCLUSIONS: The improvement of keratopathy in the surgical group was greater than that in the nonsurgical group in consideration of the more advanced severity in the surgery group at baseline. Decreased with-the-rule astigmatism can be observed at 6 months postoperatively, particularly among those with greater baseline astigmatism. However, the amount of change is small, and the outcome does not differ significantly from the nonsurgical treatment. Therefore, surgical indications should majorly base on the severity of symptoms and keratopathy.
Copyright © 2020 Shang-Te Ma et al.

Entities:  

Year:  2020        PMID: 33489332      PMCID: PMC7803214          DOI: 10.1155/2020/5073895

Source DB:  PubMed          Journal:  J Ophthalmol        ISSN: 2090-004X            Impact factor:   1.909


  28 in total

1.  Power vector analysis of the optical outcome of refractive surgery.

Authors:  L N Thibos; D Horner
Journal:  J Cataract Refract Surg       Date:  2001-01       Impact factor: 3.351

2.  Non-incisional eyelid everting suture technique for treating lower lid epiblepharon.

Authors:  Ji Won Seo; Sunah Kang; Chanjoo Ahn; Bita Esmaeli; Ho-Seok Sa
Journal:  Br J Ophthalmol       Date:  2018-03-21       Impact factor: 4.638

3.  The effect of surgical correction of epiblepharon on astigmatism in children.

Authors:  Sang Woo Park; Ji Yong Sok; Yeoung Geol Park
Journal:  J Pediatr Ophthalmol Strabismus       Date:  2008 Jan-Feb       Impact factor: 1.402

4.  Astigmatism in children with epiblepharon.

Authors:  Min-Hsiu Shih; Fu-Chin Huang
Journal:  Cornea       Date:  2007-10       Impact factor: 2.651

5.  A new method of analyzing vectors for changes in astigmatism.

Authors:  N A Alpins
Journal:  J Cataract Refract Surg       Date:  1993-07       Impact factor: 3.351

6.  Epiblepharon with inverted eyelashes in Japanese children. I. Incidence and symptoms.

Authors:  S Noda; S Hayasaka; T Setogawa
Journal:  Br J Ophthalmol       Date:  1989-02       Impact factor: 4.638

7.  Epithelial injury induces keratocyte apoptosis: hypothesized role for the interleukin-1 system in the modulation of corneal tissue organization and wound healing.

Authors:  S E Wilson; Y G He; J Weng; Q Li; A W McDowall; M Vital; E L Chwang
Journal:  Exp Eye Res       Date:  1996-04       Impact factor: 3.467

Review 8.  Management of epiblepharon: state of the art.

Authors:  Kyung In Woo; Yoon-Duck Kim
Journal:  Curr Opin Ophthalmol       Date:  2016-09       Impact factor: 3.761

9.  The clinical characteristics and surgical outcomes of epiblepharon in korean children: a 9-year experience.

Authors:  Jong Soo Kim; Sang Wook Jin; Mun Chong Hur; Yoon Hyung Kwon; Won Yeol Ryu; Woo Jin Jeong; Hee Bae Ahn
Journal:  J Ophthalmol       Date:  2014-09-14       Impact factor: 1.909

10.  AstigMATIC: an automatic tool for standard astigmatism vector analysis.

Authors:  Mathieu Gauvin; Avi Wallerstein
Journal:  BMC Ophthalmol       Date:  2018-09-21       Impact factor: 2.209

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