Literature DB >> 3346037

Fatal paracetamol poisoning in an epileptic.

N A Minton1, J A Henry, R J Frankel.   

Abstract

Treatment nomograms are used in paracetamol poisoning for indicating when antidotes should be given to prevent hepatic or renal damage. We report a fatal case of paracetamol poisoning in an epileptic taking phenytoin, in whom no antidotal treatment was given because it was not indicated.

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Year:  1988        PMID： 3346037     DOI： 10.1177/096032718800700106

Source DB:  PubMed          Journal:  Hum Toxicol        ISSN： 0144-5952


  8 in total

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3.  PharmGKB summary: pathways of acetaminophen metabolism at the therapeutic versus toxic doses.

Authors:  Liudmila L Mazaleuskaya; Katrin Sangkuhl; Caroline F Thorn; Garret A FitzGerald; Russ B Altman; Teri E Klein
Journal:  Pharmacogenet Genomics       Date:  2015-08       Impact factor: 2.089

Review 4.  Potentiation of acetaminophen hepatotoxicity by phenytoin, leading to liver transplantation.

Authors:  Scott M Suchin; David C Wolf; Young Lee; Gita Ramaswamy; Patricia A Sheiner; Marcelo Facciuto; Michael R Marvin; Leona Kim-Schluger; Edward Lebovics
Journal:  Dig Dis Sci       Date:  2005-10       Impact factor: 3.199

Review 5.  Recent developments in the management of paracetamol (acetaminophen) poisoning.

Authors:  J Janes; P A Routledge
Journal:  Drug Saf       Date:  1992 May-Jun       Impact factor: 5.606

Review 6.  Management of paracetamol overdose: current controversies.

Authors:  E Kozer; G Koren
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Review 7.  Does cytochrome P450 liver isoenzyme induction increase the risk of liver toxicity after paracetamol overdose?

Authors:  Sarbjeet S Kalsi; David M Wood; W Stephen Waring; Paul I Dargan
Journal:  Open Access Emerg Med       Date:  2011-10-13

8.  The Risk of Drug-Drug Interactions with Paracetamol in a Population of Hospitalized Geriatric Patients.

Authors:  Lykke Ida Kaas Oldenburg; Kim Peder Dalhoff; Luana Østerdal Sandoval; Charlotte Vermehren
Journal:  J Pharm (Cairo)       Date:  2020-01-19
  8 in total

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