Literature DB >> 26049587

PharmGKB summary: pathways of acetaminophen metabolism at the therapeutic versus toxic doses.

Liudmila L Mazaleuskaya1, Katrin Sangkuhl, Caroline F Thorn, Garret A FitzGerald, Russ B Altman, Teri E Klein.   

Abstract

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Year:  2015        PMID： 26049587      PMCID： PMC4498995          DOI： 10.1097/FPC.0000000000000150

Source DB:  PubMed          Journal:  Pharmacogenet Genomics        ISSN： 1744-6872            Impact factor:   2.089


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  114 in total

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3.  Differences in the single-oral-dose pharmacokinetics and urinary excretion of paracetamol and its conjugates between Hong Kong Chinese and Caucasian subjects.

Authors:  J A J H Critchley; L A H Critchley; P J Anderson; B Tomlinson
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4.  Contribution of CYP2E1 and CYP3A to acetaminophen reactive metabolite formation.

Authors:  P T Manyike; E D Kharasch; T F Kalhorn; J T Slattery
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6.  Kinetics of acetaminophen glucuronidation by UDP-glucuronosyltransferases 1A1, 1A6, 1A9 and 2B15. Potential implications in acetaminophen-induced hepatotoxicity.

Authors:  Abdul E Mutlib; Theunis C Goosen; Jonathan N Bauman; J Andrew Williams; Shaila Kulkarni; Seva Kostrubsky
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7.  Formation and disposition of the minor metabolites of acetaminophen in the hamster.

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Journal:  Drug Metab Dispos       Date:  1981 Jul-Aug       Impact factor: 3.922

Review 8.  Prostanoids in health and disease.

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9.  Prenatal acetaminophen exposure and risk of wheeze at age 5 years in an urban low-income cohort.

Authors:  Matthew S Perzanowski; Rachel L Miller; Deliang Tang; David Ali; Robin S Garfinkel; Ginger L Chew; Inge F Goldstein; Frederica P Perera; R Graham Barr
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10.  Racial variability in the UDP-glucuronosyltransferase 1 (UGT1A1) promoter: a balanced polymorphism for regulation of bilirubin metabolism?

Authors:  E Beutler; T Gelbart; A Demina
Journal:  Proc Natl Acad Sci U S A       Date:  1998-07-07       Impact factor: 11.205
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  66 in total

1.  Polymorphic Expression of UGT1A9 is Associated with Variable Acetaminophen Glucuronidation in Neonates: A Population Pharmacokinetic and Pharmacogenetic Study.

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4.  Novel Protective Role of Nicotinamide Phosphoribosyltransferase in Acetaminophen-Induced Acute Liver Injury in Mice.

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Review 7.  Long-term adverse effects of paracetamol - a review.

Authors:  J C McCrae; E E Morrison; I M MacIntyre; J W Dear; D J Webb
Journal:  Br J Clin Pharmacol       Date:  2018-07-20       Impact factor: 4.335

Review 8.  An Evolutionary Perspective on the Impact of Genomic Copy Number Variation on Human Health.

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10.  The Power of Resolution: Contextualized Understanding of Biological Responses to Liver Injury Chemicals Using High-throughput Transcriptomics and Benchmark Concentration Modeling.

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Journal:  Toxicol Sci       Date:  2019-06-01       Impact factor: 4.849
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