| Literature DB >> 33448182 |
Cuicui Lin1, Zhengyun Chen2, Chunyan Wang1, Yongmei Xi1,2.
Abstract
The pathogenesis of endometriosis is not well understood at the moment, and the lack of effective biomarkers often leads to delayed diagnosis of the disease. Lipidomics provides a new approach for the diagnosis and prediction of endometriosis. Sphingomyelin, phosphatidylcholine and phosphatidylserine in peripheral blood, endometrial fluid, peritoneal fluid and follicular fluid have good diagnostic value for endometriosis and disease classification; the lipid metabolites in the eutopic endometrium tissue are expected to be biomarkers of early endometriosis; and the lipid metabolites in peripheral blood are also of great value for predicting endometriosis-related infertility. The development of lipidomics technique will further advance the progress on the pathogenesis, prediction, diagnosis and treatment of endometriosis.Entities:
Keywords: Biomarker; Endometriosis; Lipidomics; Review
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Year: 2020 PMID: 33448182 PMCID: PMC8800742 DOI: 10.3785/j.issn.1008-9292.2020.12.14
Source DB: PubMed Journal: Zhejiang Da Xue Xue Bao Yi Xue Ban ISSN: 1008-9292