| Literature DB >> 33414387 |
Dehua Yang1,2, Qingtong Zhou3, Viktorija Labroska1,4, Shanshan Qin5, Sanaz Darbalaei1,4, Yiran Wu5, Elita Yuliantie1,4, Linshan Xie5,6, Houchao Tao5, Jianjun Cheng5, Qing Liu1,2, Suwen Zhao5,6, Wenqing Shui7,8, Yi Jiang9, Ming-Wei Wang10,11,12,13,14,15.
Abstract
As one of the most successful therapeutic target families, G protein-coupled receptors (GPCRs) have experienced a transformation from random ligand screening to knowledge-driven drug design. We are eye-witnessing tremendous progresses made recently in the understanding of their structure-function relationships that facilitated drug development at an unprecedented pace. This article intends to provide a comprehensive overview of this important field to a broader readership that shares some common interests in drug discovery.Entities:
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Year: 2021 PMID： 33414387 PMCID： PMC7790836 DOI： 10.1038/s41392-020-00435-w
Source DB: PubMed Journal: Signal Transduct Target Ther ISSN： 2059-3635