Literature DB >> 3340549

A 13 bp palindrome is a functional estrogen responsive element and interacts specifically with estrogen receptor.

L Klein-Hitpass1, G U Ryffel, E Heitlinger, A C Cato.   

Abstract

Sequences located upstream of the transcription initiation site of the Xenopus vitellogenin A2 (vit A2) gene contain a hormone dependent enhancer that confers estrogen control to the heterologous thymidine kinase (tk) promoter. As a minimal functional estrogen responsive element (ERE), we have defined the 13 bp palindrome GGTCACAGTGACC. This ERE binds estrogen receptor preferentially in vitro. Although the ERE shares some structural features with the glucocorticoid responsive element (GRE) it is distinct from this element since it neither binds glucocorticoid receptor in vitro nor does it confer glucocorticoid inducibility to a fusion gene. Point mutations within the ERE decrease its affinity for the estrogen receptor and result in a complete loss of estrogen inducibility.

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Year:  1988        PMID： 3340549      PMCID： PMC334683          DOI： 10.1093/nar/16.2.647

Source DB:  PubMed          Journal:  Nucleic Acids Res        ISSN： 0305-1048            Impact factor:   16.971


  39 in total

1.  Glucocorticoid-binding proteins of rat liver cytosol. I. Separation and identification of the binding proteins.

Authors:  M Beato; P Feigelson
Journal:  J Biol Chem       Date:  1972-12-25       Impact factor: 5.157

2.  DNA sequences bound specifically by glucocorticoid receptor in vitro render a heterologous promoter hormone responsive in vivo.

Authors:  V L Chandler; B A Maler; K R Yamamoto
Journal:  Cell       Date:  1983-06       Impact factor: 41.582

3.  pEMBL: a new family of single stranded plasmids.

Authors:  L Dente; G Cesareni; R Cortese
Journal:  Nucleic Acids Res       Date:  1983-03-25       Impact factor: 16.971

Review 4.  Enhancer elements.

Authors:  G Khoury; P Gruss
Journal:  Cell       Date:  1983-06       Impact factor: 41.582

5.  Specific binding of the glucocorticoid-receptor complex to the mouse mammary tumor proviral promoter region.

Authors:  M Pfahl
Journal:  Cell       Date:  1982-12       Impact factor: 41.582

6.  Regulated expression of human growth hormone genes in mouse cells.

Authors:  D M Robins; I Paek; P H Seeburg; R Axel
Journal:  Cell       Date:  1982-06       Impact factor: 41.582

7.  Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cells.

Authors:  C M Gorman; L F Moffat; B H Howard
Journal:  Mol Cell Biol       Date:  1982-09       Impact factor: 4.272

8.  The activated glucocorticoid receptor of rat liver. Purification and physical characterization.

Authors:  H M Westphal; M Beato
Journal:  Eur J Biochem       Date:  1980-05

9.  Structure and sequence of the promoter area and of a 5' upstream demethylation site of the estrogen-regulated chicken vitellogenin ii gene.

Authors:  M Geiser; I W Mattaj; A F Wilks; M Seldran; J P Jost
Journal:  J Biol Chem       Date:  1983-07-25       Impact factor: 5.157

10.  Glucocorticoid regulation of mouse mammary tumor virus: identification of a short essential DNA region.

Authors:  E Buetti; H Diggelmann
Journal:  EMBO J       Date:  1983       Impact factor: 11.598
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  98 in total

1.  17beta-estradiol inhibits apoptosis in MCF-7 cells, inducing bcl-2 expression via two estrogen-responsive elements present in the coding sequence.

Authors:  B Perillo; A Sasso; C Abbondanza; G Palumbo
Journal:  Mol Cell Biol       Date:  2000-04       Impact factor: 4.272

2.  Structure, alternative splicing and chromosomal localization of the cystatin-related epididymal spermatogenic gene.

Authors:  G A Cornwall; N Hsia; H G Sutton
Journal:  Biochem J       Date:  1999-05-15       Impact factor: 3.857

3.  Common double- and single-stranded DNA binding factor for a sterol regulatory element.

Authors:  H C Stark; O Weinberger; J Weinberger
Journal:  Proc Natl Acad Sci U S A       Date:  1992-03-15       Impact factor: 11.205

4.  The proton-driven dissociation of oestradiol-receptor dimers as a preparative tool. Isolation of a 32 kDa fragment from porcine uteri and assignment of C-terminal origin by partial sequencing.

Authors:  H H Thole; P W Jungblut; F Jakob
Journal:  Biochem J       Date:  1991-06-15       Impact factor: 3.857

5.  Expression profiling of the maize flavonoid pathway genes controlled by estradiol-inducible transcription factors CRC and P.

Authors:  W Bruce; O Folkerts; C Garnaat; O Crasta; B Roth; B Bowen
Journal:  Plant Cell       Date:  2000-01       Impact factor: 11.277

6.  Functional interaction of hybrid response elements with wild-type and mutant steroid hormone receptors.

Authors:  M Truss; G Chalepakis; E P Slater; S Mader; M Beato
Journal:  Mol Cell Biol       Date:  1991-06       Impact factor: 4.272

7.  Identification of novel steroid-response elements.

Authors:  Z Nawaz; M J Tsai; D P McDonnell; B W O'Malley
Journal:  Gene Expr       Date:  1992

8.  Pituitary follicle-stimulating hormone (FSH) induces CREM gene expression in Sertoli cells: involvement in long-term desensitization of the FSH receptor.

Authors:  L Monaco; N S Foulkes; P Sassone-Corsi
Journal:  Proc Natl Acad Sci U S A       Date:  1995-11-07       Impact factor: 11.205

9.  Long-range transcriptional control of progesterone receptor gene expression.

Authors:  Jamie Bonéy-Montoya; Yvonne S Ziegler; Carol D Curtis; Jonathan A Montoya; Ann M Nardulli
Journal:  Mol Endocrinol       Date:  2009-12-01

10.  Inhibition of AP-1 binding and transcription by gold and selenium involving conserved cysteine residues in Jun and Fos.

Authors:  M L Handel; C K Watts; A deFazio; R O Day; R L Sutherland
Journal:  Proc Natl Acad Sci U S A       Date:  1995-05-09       Impact factor: 11.205
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