Literature DB >> 10872340

Glucocorticoid regulation of mouse mammary tumor virus: identification of a short essential DNA region.

E Buetti1, H Diggelmann.   

Abstract

Transcription of mouse mammary tumor virus (MMTV) DNA is stimulated by steroid hormones. To determine the DNA sequences involved in this regulation, we constructed a plasmid containing the MMTV long terminal repeat (LTR) in front of the coding region of the herpes simplex thymidine kinase gene, from which the promoter had been removed. Portions of the LTR were removed by the nuclease Ba/31, and the deleted molecules were recloned and tested for transcriptional activity in transfections of Ltk-aprt- cells. Stably transfected cell clones were selected and hormone-dependent transcription from the MMTV promoter was studied by the S1 nuclease mapping method. The results show that DNA sequences between -105 and -204 base pairs upstream from the initiation site of viral transcription are required for glucocorticoid stimulation.

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Year:  1983        PMID： 10872340      PMCID： PMC555292          DOI： 10.1002/j.1460-2075.1983.tb01601.x

Source DB:  PubMed          Journal:  EMBO J        ISSN： 0261-4189            Impact factor:   11.598


  45 in total

1.  SELECTION OF HYBRIDS FROM MATINGS OF FIBROBLASTS IN VITRO AND THEIR PRESUMED RECOMBINANTS.

Authors:  J W LITTLEFIELD
Journal:  Science       Date:  1964-08-14       Impact factor: 47.728

2.  Capping of eucaryotic mRNAs.

Authors:  A J Shatkin
Journal:  Cell       Date:  1976-12       Impact factor: 41.582

3.  Biochemical and physiological mechanisms in glucocorticoid hormone induction of mouse mammary tumor virus.

Authors:  E M Scolnick; H A Young; W P Parks
Journal:  Virology       Date:  1976-01       Impact factor: 3.616

4.  Murine mammary tumor virus: characterization of infection of nonmurine cells.

Authors:  A B Vaidya; E Y Lasfargues; G Heubel; J C Lasfargues; D H Moore
Journal:  J Virol       Date:  1976-06       Impact factor: 5.103

5.  Sizing and mapping of early adenovirus mRNAs by gel electrophoresis of S1 endonuclease-digested hybrids.

Authors:  A J Berk; P A Sharp
Journal:  Cell       Date:  1977-11       Impact factor: 41.582

6.  Dexamethasone-mediated induction of mouse mammary tumor virus RNA: a system for studying glucocorticoid action.

Authors:  G M Ringold; K R Yamamoto; G M Tomkins; M Bishop; H E Varmus
Journal:  Cell       Date:  1975-11       Impact factor: 41.582

7.  Glucocorticoid-stimulated accumulation of mouse mammary tumor virus RNA: increased rate of synthesis of viral RNA.

Authors:  G M Ringold; K R Yamamoto; J M Bishop; H E Varmus
Journal:  Proc Natl Acad Sci U S A       Date:  1977-07       Impact factor: 11.205

8.  Steroid induction of mouse mammary tumor virus: effect upon synthesis and degradation of viral RNA.

Authors:  H A Young; T Y Shih; E M Scolnick; W P Parks
Journal:  J Virol       Date:  1977-01       Impact factor: 5.103

9.  Infection of cultured rat hepatoma cells by mouse mammary tumor virus.

Authors:  G M Ringold; R D Cardiff; H E Varmus; K R Yamamoto
Journal:  Cell       Date:  1977-01       Impact factor: 41.582

10.  Dexamethasone stimulation of murine mammary tumor virus expression: a tissue culture source of virus.

Authors:  W P Parks; E M Scolnick; E H Kozikowski
Journal:  Science       Date:  1974-04-12       Impact factor: 47.728
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  47 in total

1.  Mutations in the hormone regulatory element of mouse mammary tumor virus differentially affect the response to progestins, androgens, and glucocorticoids.

Authors:  P L Gowland; E Buetti
Journal:  Mol Cell Biol       Date:  1989-09       Impact factor: 4.272

Review 2.  Factors controlling the expression of mouse mammary tumour virus.

Authors:  W H Günzburg; B Salmons
Journal:  Biochem J       Date:  1992-05-01       Impact factor: 3.857

3.  Identification of a novel mammary cell line-specific enhancer element in the long terminal repeat of mouse mammary tumor virus, which interacts with its hormone-responsive element.

Authors:  S Yanagawa; H Tanaka; A Ishimoto
Journal:  J Virol       Date:  1991-01       Impact factor: 5.103

4.  Dual function of a nuclear factor I binding site in MMTV transcription regulation.

Authors:  E Buetti; B Kühnel; H Diggelmann
Journal:  Nucleic Acids Res       Date:  1989-04-25       Impact factor: 16.971

5.  Multiple regulatory domains in the mouse mammary tumor virus long terminal repeat revealed by analysis of fusion genes in transgenic mice.

Authors:  T A Stewart; P G Hollingshead; S L Pitts
Journal:  Mol Cell Biol       Date:  1988-01       Impact factor: 4.272

6.  Differential transformation of C3H10T1/2 cells by v-mos: sequential expression of transformation parameters.

Authors:  F A van der Hoorn; V Müller
Journal:  Mol Cell Biol       Date:  1985-09       Impact factor: 4.272

7.  Differential expression of endogenous mouse mammary tumor virus genes during development of the BALB/c mammary gland.

Authors:  J E Knepper; D Medina; J S Butel
Journal:  J Virol       Date:  1986-08       Impact factor: 5.103

8.  Identification of estrogen-responsive DNA sequences by transient expression experiments in a human breast cancer cell line.

Authors:  A Seiler-Tuyns; P Walker; E Martinez; A M Mérillat; F Givel; W Wahli
Journal:  Nucleic Acids Res       Date:  1986-11-25       Impact factor: 16.971

9.  Characterization of endogenous retroviruses in sheep.

Authors:  Nikolai Klymiuk; Mathias Müller; Gottfried Brem; Bernhard Aigner
Journal:  J Virol       Date:  2003-10       Impact factor: 5.103

10.  Inhibition of chromatin assembly in Xenopus oocytes correlates with derepression of the mouse mammary tumor virus promoter.

Authors:  T Perlmann; O Wrange
Journal:  Mol Cell Biol       Date:  1991-10       Impact factor: 4.272
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