Literature DB >> 3340270

Vasoactive intestinal peptide gene expression from embryos to aging rats.

I Gozes1, P Schächter, Y Shani, E Giladi.   

Abstract

Vasoactive intestinal peptide (VIP) gene transcripts were demonstrated by RNA blot hybridization using VIP-specific RNA hybridization probes. High levels of expression were observed as early as in 16-day-old embryos. In aging rats, the VIP-mRNA levels were reduced significantly (in the cerebral cortex) as compared to 21-day-old rats. Our results suggest a role for the VIP gene protein products during embryonal development. During aging processes the decrease in VIP gene transcripts may be a consequence of either a reduction in the transcriptional activity of VIP neurons or death of VIP-producing cells.

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Year:  1988        PMID: 3340270     DOI: 10.1159/000124886

Source DB:  PubMed          Journal:  Neuroendocrinology        ISSN: 0028-3835            Impact factor:   4.914


  18 in total

1.  VIP, from gene to behavior and back: summarizing my 25 years of research.

Authors:  Illana Gozes
Journal:  J Mol Neurosci       Date:  2008-07-08       Impact factor: 3.444

2.  Activity-dependent neuroprotective protein (ADNP) expression in the amyloid precursor protein/presenilin 1 mouse model of Alzheimer's disease.

Authors:  Rafael Fernandez-Montesinos; Manuel Torres; David Baglietto-Vargas; Antonia Gutierrez; Illana Gozes; Javier Vitorica; David Pozo
Journal:  J Mol Neurosci       Date:  2009-10-21       Impact factor: 3.444

Review 3.  A VIP hybrid antagonist: from developmental neurobiology to clinical applications.

Authors:  I Gozes; M Fridkin; D E Brenneman
Journal:  Cell Mol Neurobiol       Date:  1995-12       Impact factor: 5.046

4.  Protection against developmental deficiencies by a lipophilic VIP analogue.

Authors:  I Gozes; M Bachar; A Bardea; A Davidson; S Rubinraut; M Fridkin
Journal:  Neurochem Res       Date:  1998-05       Impact factor: 3.996

5.  Ontogeny of vasoactive intestinal peptide gene expression in rat brain.

Authors:  M Graber; J M Burgunder
Journal:  Anat Embryol (Berl)       Date:  1996-12

Review 6.  Regulation of VIP gene expression in general. Human lung cancer cells in particular.

Authors:  A Davidson; T W Moody; I Gozes
Journal:  J Mol Neurosci       Date:  1996       Impact factor: 3.444

Review 7.  Activity-dependent neurotrophic factor (ADNF). An extracellular neuroprotective chaperonin?

Authors:  I Gozes; D E Brenneman
Journal:  J Mol Neurosci       Date:  1996       Impact factor: 3.444

Review 8.  VIP as a cell-growth and differentiation neuromodulator role in neurodevelopment.

Authors:  J M Muller; V Lelievre; L Becq-Giraudon; A C Meunier
Journal:  Mol Neurobiol       Date:  1995 Apr-Jun       Impact factor: 5.590

9.  Maternal vasoactive intestinal peptide and the regulation of embryonic growth in the rodent.

Authors:  J M Hill; S K McCune; R J Alvero; G W Glazner; K A Henins; S F Stanziale; J R Keimowitz; D E Brenneman
Journal:  J Clin Invest       Date:  1996-01-01       Impact factor: 14.808

10.  Vasoactive intestinal peptide (VIP) regulates activity-dependent neuroprotective protein (ADNP) expression in vivo.

Authors:  Eliezer Giladi; Joanna M Hill; Efrat Dresner; Conor M Stack; Illana Gozes
Journal:  J Mol Neurosci       Date:  2007-10-02       Impact factor: 3.444

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