| Literature DB >> 33398067 |
Shuang Liang1, Huixiang Liu1, Yu Gu2,3,4, Xiuhua Guo5,6, Hongjun Li7, Li Li7, Zhiyuan Wu5,6, Mengyang Liu5,6, Lixin Tao5,6.
Abstract
Coronavirus disease 2019 (COVID-19) is a global pandemic posing significant health risks. The diagnostic test sensitivity of COVID-19 is limited due to irregularities in specimen handling. We propose a deep learning framework that identifies COVID-19 from medical images as an auxiliary testing method to improve diagnostic sensitivity. We use pseudo-coloring methods and a platform for annotating X-ray and computed tomography images to train the convolutional neural network, which achieves a performance similar to that of experts and provides high scores for multiple statistical indices (F1 scores > 96.72% (0.9307, 0.9890) and specificity >99.33% (0.9792, 1.0000)). Heatmaps are used to visualize the salient features extracted by the neural network. The neural network-based regression provides strong correlations between the lesion areas in the images and five clinical indicators, resulting in high accuracy of the classification framework. The proposed method represents a potential computer-aided diagnosis method for COVID-19 in clinical practice.Entities:
Year: 2021 PMID: 33398067 DOI: 10.1038/s42003-020-01535-7
Source DB: PubMed Journal: Commun Biol ISSN: 2399-3642