John Sincavage1, Brittany Robinson2, Vanessa J Msosa3, Chawezi Katete3, Laura N Purcell4, Anthony Charles5. 1. Northwestern University Feinberg School of Medicine, United States. 2. University of California San Francisco School of Medicine, United States. 3. Kamuzu Central Hospital, Lilongwe, Malawi. 4. Department of Surgery, University of North Carolina at Chapel Hill, United States. 5. Kamuzu Central Hospital, Lilongwe, Malawi; Department of Surgery, University of North Carolina at Chapel Hill, United States. Electronic address: anthchar@med.unc.edu.
Abstract
INTRODUCTION: Anemia is a common and potentially modifiable condition in sub-Saharan Africa. We sought to determine the role of preoperative anemia on post laparotomy abdominal complications. METHODS: We conducted a six-month prospective, observational study of patients age >12 years following laparotomy at a tertiary hospital in Malawi. The outcome was the occurrence of abdominal complications. Poisson regression analyses estimated the risk of abdominal complications in patients with moderate/severe anemia. RESULTS: Of 280 patients, most were male (76.4%) with median age of 35 years (IQR 24-50). Abdominal complications developed in 34 patients (15.2%). Of the 224 patients with known preoperative hemoglobin 54 (20.7%) were moderately or severely anemic at the time of surgery. Patients with moderate-to-severe anemia had an increased risk of abdominal complications (RR 4.44, 95% CI 2.0-9.6). CONCLUSION: Anemia is a common but modifiable comorbidity among laparotomy patients and independently increases the risk of abdominal complications.
INTRODUCTION: Anemia is a common and potentially modifiable condition in sub-Saharan Africa. We sought to determine the role of preoperative anemia on post laparotomy abdominal complications. METHODS: We conducted a six-month prospective, observational study of patients age >12 years following laparotomy at a tertiary hospital in Malawi. The outcome was the occurrence of abdominal complications. Poisson regression analyses estimated the risk of abdominal complications in patients with moderate/severe anemia. RESULTS: Of 280 patients, most were male (76.4%) with median age of 35 years (IQR 24-50). Abdominal complications developed in 34 patients (15.2%). Of the 224 patients with known preoperative hemoglobin 54 (20.7%) were moderately or severely anemic at the time of surgery. Patients with moderate-to-severe anemia had an increased risk of abdominal complications (RR 4.44, 95% CI 2.0-9.6). CONCLUSION: Anemia is a common but modifiable comorbidity among laparotomy patients and independently increases the risk of abdominal complications.
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