Literature DB >> 33377350

[Research progress in the osteogenetic mechanism of strontium].

Ning-Ying Zhong1, Li-Ping Wang2.   

Abstract

Strontium (Sr) is an essential trace element and widely exists in nature. It plays an important role in the in vivo regulation of bone metabolism. Sr locates below Fe in the periodic table, and its chemical structure and polarity are similar to those of Ca. It can induce bone mesenchymal stem cells to differentiate into osteoblasts by inhibiting the activity of osteoclasts and reducing bone resorption. It promotes bone formation through a series of related pathways. The mechanism of Sr regulation of bone metabolism has been extensively researched in recent years. The current study aims to investigate the mechanism of Sr and provide a theoretical basis for its clinical application.

Entities:  

Keywords:  bone metabolism; mechanism of action; strontium

Mesh：

Substances：

Year:  2020        PMID： 33377350      PMCID： PMC7738917          DOI： 10.7518/hxkq.2020.06.016

Source DB:  PubMed          Journal:  Hua Xi Kou Qiang Yi Xue Za Zhi        ISSN： 1000-1182


  52 in total

1.  Coexpression of virulence and fosfomycin susceptibility in Listeria: molecular basis of an antimicrobial in vitro-in vivo paradox.

Authors:  Mariela Scortti; Lizeth Lacharme-Lora; Martin Wagner; Isabel Chico-Calero; Patrizia Losito; José A Vázquez-Boland
Journal:  Nat Med       Date:  2006-04-23       Impact factor: 53.440

2.  Effects of strontium on proliferation and differentiation of rat bone marrow mesenchymal stem cells.

Authors:  Yunfeng Li; Jihua Li; Songsong Zhu; En Luo; Ge Feng; Qianming Chen; Jing Hu
Journal:  Biochem Biophys Res Commun       Date:  2012-01-27       Impact factor: 3.575

3.  Strontium promotes osteogenic differentiation of mesenchymal stem cells through the Ras/MAPK signaling pathway.

Authors:  Songlin Peng; Guangqian Zhou; Keith D K Luk; Kenneth M C Cheung; Zhaoyang Li; Wing Moon Lam; Zhongjun Zhou; William W Lu
Journal:  Cell Physiol Biochem       Date:  2009-02-18

4.  Determination of strontium in human whole blood by ICP-AES.

Authors:  M Piette; B Desmet; R Dams
Journal:  Sci Total Environ       Date:  1994-01-25       Impact factor: 7.963

5.  Strontium ranelate increases osteoblast activity.

Authors:  Monica Marletti Almeida; Edson Parra Nani; Lucas Novaes Teixeira; Daiane Cristina Peruzzo; Júlio César Joly; Marcelo Henrique Napimoga; Elizabeth Ferreira Martinez
Journal:  Tissue Cell       Date:  2016-04-16       Impact factor: 2.466

6.  Essential role of nuclear factor of activated T cells (NFAT)-mediated Wnt signaling in osteoblast differentiation induced by strontium ranelate.

Authors:  Olivia Fromigué; Eric Haÿ; Alain Barbara; Pierre J Marie
Journal:  J Biol Chem       Date:  2010-06-16       Impact factor: 5.157

7.  Strontium ranelate prevents the deleterious action of advanced glycation endproducts on osteoblastic cells via calcium channel activation.

Authors:  Juan Manuel Fernández; María Silvina Molinuevo; Claudia Sedlinsky; León Schurman; Ana María Cortizo; Antonio Desmond McCarthy
Journal:  Eur J Pharmacol       Date:  2013-03-13       Impact factor: 4.432

8.  Compositional and material properties of rat bone after bisphosphonate and/or Strontium ranelate drug treatment.

Authors:  Yuchin Wu; Samer M Adeeb; M John Duke; David Munoz-Paniagua; Michael R Doschak
Journal:  J Pharm Pharm Sci       Date:  2013       Impact factor: 2.327

9.  Strontium ranelate analgesia in arthritis models is associated to decreased cytokine release and opioid-dependent mechanisms.

Authors:  Rodolfo de Melo Nunes; Morgana Ramos Martins; Francisco Saraiva da Silva Junior; Ana Caroline Rocha de Melo Leite; Virgínia Claudia Carneiro Girão; Fernando de Queiroz Cunha; Aryana Lushese Lima Feitosa Marinho; Ana Carolina Matias Dinelly Pinto; Francisco Airton Castro Rocha
Journal:  Inflamm Res       Date:  2015-08-06       Impact factor: 4.575

10.  The effect of strontium ranelate on serum insulin like growth factor-1 and leptin levels in osteoporotic post-menopausal women: a prospective study.

Authors:  Ibrahim Gulhan; Sibel Bilgili; Rezzan Gunaydin; Sibel Gulhan; Cemal Posaci
Journal:  Arch Gynecol Obstet       Date:  2008-03-06       Impact factor: 2.344
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