| Literature DB >> 33361257 |
Giske Opheim1, Anja van der Kolk2, Karin Markenroth Bloch2, Albert J Colon2, Kathryn A Davis2, Thomas R Henry2, Jacobus F A Jansen2, Stephen E Jones2, Jullie W Pan2, Karl Rössler2, Joel M Stein2, Maria C Strandberg2, Siegfried Trattnig2, Pierre-Francois Van de Moortele2, Maria Isabel Vargas2, Irene Wang2, Fabrice Bartolomei2, Neda Bernasconi2, Andrea Bernasconi2, Boris Bernhardt2, Isabella Björkman-Burtscher2, Mirco Cosottini2, Sandhitsu R Das2, Lucie Hertz-Pannier2, Sara Inati2, Michael T Jurkiewicz2, Ali R Khan2, Shuli Liang2, Ruoyun Emily Ma2, Srinivasan Mukundan2, Heath Pardoe2, Lars H Pinborg2, Jonathan R Polimeni2, Jean-Philippe Ranjeva2, Esther Steijvers2, Steven Stufflebeam2, Tim J Veersema2, Alexandre Vignaud2, Natalie Voets2, Serge Vulliemoz2, Christopher J Wiggins2, Rong Xue2, Renzo Guerrini2, Maxime Guye2.
Abstract
Identifying a structural brain lesion on MRI has important implications in epilepsy and is the most important factor that correlates with seizure freedom after surgery in patients with drug-resistant focal onset epilepsy. However, at conventional magnetic field strengths (1.5 and 3T), only approximately 60%-85% of MRI examinations reveal such lesions. Over the last decade, studies have demonstrated the added value of 7T MRI in patients with and without known epileptogenic lesions from 1.5 and/or 3T. However, translation of 7T MRI to clinical practice is still challenging, particularly in centers new to 7T, and there is a need for practical recommendations on targeted use of 7T MRI in the clinical management of patients with epilepsy. The 7T Epilepsy Task Force-an international group representing 21 7T MRI centers with experience from scanning over 2,000 patients with epilepsy-would hereby like to share its experience with the neurology community regarding the appropriate clinical indications, patient selection and preparation, acquisition protocols and setup, technical challenges, and radiologic guidelines for 7T MRI in patients with epilepsy. This article mainly addresses structural imaging; in addition, it presents multiple nonstructural MRI techniques that benefit from 7T and hold promise as future directions in epilepsy. Answering to the increased availability of 7T MRI as an approved tool for diagnostic purposes, this article aims to provide guidance on clinical 7T MRI epilepsy management by giving recommendations on referral, suitable 7T MRI protocols, and image interpretation.Entities:
Mesh:
Year: 2020 PMID: 33361257 PMCID: PMC8055334 DOI: 10.1212/WNL.0000000000011413
Source DB: PubMed Journal: Neurology ISSN: 0028-3878 Impact factor: 9.910