Literature DB >> 33271351

Failure Modes in IROC Photon Liver Phantom Irradiations.

Paige A Taylor1, Paola E Alvarez2, Hunter Mehrens1, David S Followill1.   

Abstract

PURPOSE: Our purpose was to analyze and classify the patterns of failure for irradiations of the Imaging and Radiation Oncology Core photon liver phantom. METHODS AND MATERIALS: Imaging and Radiation Oncology Core's anthropomorphic liver phantom simulates multitarget liver disease with respiratory motion. Two hundred forty-nine liver phantom results from 2013 to 2019 were analyzed. Phantom irradiations that failed were categorized by the error attributed to the failure. Phantom results were also compared by demographic data, such as machine type, treatment planning system, motion management technique, number of isocenters, and whether the phantom was a first time or repeat irradiation.
RESULTS: The failure rate for the liver phantom was 27%. From the 68 irradiations that did not pass, 5 failure modes were identified. The most common failure mode was localization errors in the direction of motion, with over 50% of failures attributed to this mode. The second-most common failure mode was systematic dose errors. The internal target volume technique performed worse than other motion management techniques. Failure modes were different by the number of isocenters used, with multi-isocenter irradiations having more failure modes in a single phantom irradiation.
CONCLUSIONS: Motion management techniques and proper alignment of moving targets play a large role in the successful irradiation of the liver phantom. These errors should be examined to ensure accurate patient treatment for liver disease or other sites where multiple moving targets are present.
Copyright © 2020 American Society for Radiation Oncology. Published by Elsevier Inc. All rights reserved.

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Year:  2020        PMID: 33271351      PMCID: PMC8102375          DOI: 10.1016/j.prro.2020.11.008

Source DB:  PubMed          Journal:  Pract Radiat Oncol        ISSN: 1879-8500


  13 in total

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Review 2.  Organ motion and its management.

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4.  Design and implementation of an anthropomorphic quality assurance phantom for intensity-modulated radiation therapy for the Radiation Therapy Oncology Group.

Authors:  Andrea Molineu; David S Followill; Peter A Balter; William F Hanson; Michael T Gillin; M Saiful Huq; Avraham Eisbruch; Geoffrey S Ibbott
Journal:  Int J Radiat Oncol Biol Phys       Date:  2005-10-01       Impact factor: 7.038

5.  Technical challenges in liver stereotactic body radiation therapy: reflecting on the progress.

Authors:  Jonas D Fontenot; Eric E Klein
Journal:  Int J Radiat Oncol Biol Phys       Date:  2013-12-01       Impact factor: 7.038

6.  Validation of a new grid-based Boltzmann equation solver for dose calculation in radiotherapy with photon beams.

Authors:  Oleg N Vassiliev; Todd A Wareing; John McGhee; Gregory Failla; Mohammad R Salehpour; Firas Mourtada
Journal:  Phys Med Biol       Date:  2010-01-07       Impact factor: 3.609

7.  Credentialing results from IMRT irradiations of an anthropomorphic head and neck phantom.

Authors:  Andrea Molineu; Nadia Hernandez; Trang Nguyen; Geoffrey Ibbott; David Followill
Journal:  Med Phys       Date:  2013-02       Impact factor: 4.071

8.  Algorithms used in heterogeneous dose calculations show systematic differences as measured with the Radiological Physics Center's anthropomorphic thorax phantom used for RTOG credentialing.

Authors:  Stephen F Kry; Paola Alvarez; Andrea Molineu; Carrie Amador; James Galvin; David S Followill
Journal:  Int J Radiat Oncol Biol Phys       Date:  2013-01-01       Impact factor: 7.038

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Review 10.  Strategies to tackle the challenges of external beam radiotherapy for liver tumors.

Authors:  Michael I Lock; Jonathan Klein; Hans T Chung; Joseph M Herman; Edward Y Kim; William Small; Nina A Mayr; Simon S Lo
Journal:  World J Hepatol       Date:  2017-05-18
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  1 in total

1.  Adoption of respiratory motion management in radiation therapy.

Authors:  Alex Burton; Sabeena Beveridge; Nicholas Hardcastle; Jessica Lye; Masoumeh Sanagou; Rick Franich
Journal:  Phys Imaging Radiat Oncol       Date:  2022-09-13
  1 in total

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