Masahiro Okada1, Aravindakshan Parthasarathy2,3, D Bradley Welling3,4, M Charles Liberman2,3,4, Stéphane F Maison2,3,4. 1. Department of Otolaryngology-Head & Neck Surgery, Ehime University Graduate School of Medicine, Tōon, Ehime, Japan. 2. Eaton-Peabody Laboratories, Massachusetts Eye & Ear, Boston, Massachusetts, USA. 3. Department of Otolaryngology-Head & Neck Surgery, Harvard Medical School, Boston, Massachusetts, USA. 4. Harvard Program in Speech and Hearing Bioscience and Technology, Boston, Massachusetts, USA.
Abstract
OBJECTIVES: This retrospective study tests the hypothesis that patients who have recovered from idiopathic sudden sensorineural hearing loss (SSNHL) show deficits in word recognition tasks that cannot be entirely explained by a loss in audibility. DESIGN: We reviewed the audiologic profile of 166 patients presenting with a unilateral SSNHL. Hearing loss severity, degree of threshold recovery, residual hearing loss, and word recognition performance were considered as outcome variables. Age, route of treatment, delay between SSNHL onset and treatment, and audiogram configuration were considered as predictor variables. RESULTS: Severity, residual hearing loss, and recovery were highly variable across patients. While age and onset-treatment delay could not account for the severity, residual hearing loss and recovery in thresholds, configuration of the SSNHL and overall inner ear status as measured by thresholds on the contralateral ear were predictive of threshold recovery. Speech recognition performance was significantly poorer than predicted by the speech intelligibility curve derived from the patient's audiogram. CONCLUSIONS: SSNHL is associated with (1) changes in thresholds that are consistent with ischemia and (2) speech intelligibility deficits that cannot be entirely explained by a change in hearing sensitivity.
OBJECTIVES: This retrospective study tests the hypothesis that patients who have recovered from idiopathic sudden sensorineural hearing loss (SSNHL) show deficits in word recognition tasks that cannot be entirely explained by a loss in audibility. DESIGN: We reviewed the audiologic profile of 166 patients presenting with a unilateral SSNHL. Hearing loss severity, degree of threshold recovery, residual hearing loss, and word recognition performance were considered as outcome variables. Age, route of treatment, delay between SSNHL onset and treatment, and audiogram configuration were considered as predictor variables. RESULTS: Severity, residual hearing loss, and recovery were highly variable across patients. While age and onset-treatment delay could not account for the severity, residual hearing loss and recovery in thresholds, configuration of the SSNHL and overall inner ear status as measured by thresholds on the contralateral ear were predictive of threshold recovery. Speech recognition performance was significantly poorer than predicted by the speech intelligibility curve derived from the patient's audiogram. CONCLUSIONS: SSNHL is associated with (1) changes in thresholds that are consistent with ischemia and (2) speech intelligibility deficits that cannot be entirely explained by a change in hearing sensitivity.
Authors: Thomas H Alexander; Michael H Weisman; Jennifer M Derebery; Mark A Espeland; Bruce J Gantz; A Julianna Gulya; Paul E Hammerschlag; Maureen Hannley; Gordon B Hughes; Richard Moscicki; Ralph A Nelson; John K Niparko; Steven D Rauch; Steven A Telian; Patrick E Brookhouser; Jeffrey P Harris Journal: Otol Neurotol Date: 2009-06 Impact factor: 2.311
Authors: Kelsie J Grant; Aravindakshan Parthasarathy; Viacheslav Vasilkov; Benjamin Caswell-Midwinter; Maria E Freitas; Victor de Gruttola; Daniel B Polley; M Charles Liberman; Stéphane F Maison Journal: Sci Rep Date: 2022-06-23 Impact factor: 4.996
Authors: Anita M Mepani; Sarah Verhulst; Kenneth E Hancock; Markus Garrett; Viacheslav Vasilkov; Kara Bennett; Victor de Gruttola; M Charles Liberman; Stéphane F Maison Journal: J Neurophysiol Date: 2021-03-03 Impact factor: 2.714