Literature DB >> 33212421

Update on latest advances in time-of-flight PET.

Suleman Surti1, Joel S Karp2.   

Abstract

This paper provides an update on time-of-flight (TOF) PET with a focus on latest hardware developments leading to current commercial PET/CT instruments. We describe advances in scintillator development, new photosensors and associated electronics readout, and detector designs for utilization in complete systems. Next, we introduce the latest commercial PET/CT scanners based on the aforementioned technologies, and discuss the detector design choices made that are relevant to differences in the system performance. Finally, we end with a discussion of the latest performance benchmarks for improved timing in PET detectors, challenges in scaling this performance to a complete system, and the outlook towards achieving a sub-50 ps coincidence timing resolution (CTR) in a PET detector.
Copyright © 2020 Associazione Italiana di Fisica Medica. Published by Elsevier Ltd. All rights reserved.

Entities:  

Keywords:  Coincidence timing resolution; Scintillator; SiPM; Time-of-flight PET

Mesh：

Year:  2020        PMID： 33212421      PMCID： PMC7749844          DOI： 10.1016/j.ejmp.2020.10.031

Source DB:  PubMed          Journal:  Phys Med        ISSN： 1120-1797            Impact factor:   2.685


  31 in total

1.  Design considerations for PET scanners.

Authors:  G Muehllrhner; J S Karp; S Surti
Journal:  Q J Nucl Med       Date:  2002-03

2.  DOI Determination by Rise Time Discrimination in Single-Ended Readout for TOF PET Imaging.

Authors:  R I Wiener; S Surti; J S Karp
Journal:  IEEE Trans Nucl Sci       Date:  2013-06       Impact factor: 1.679

3.  Studies of a Next-Generation Silicon-Photomultiplier-Based Time-of-Flight PET/CT System.

Authors:  David F C Hsu; Ezgi Ilan; William T Peterson; Jorge Uribe; Mark Lubberink; Craig S Levin
Journal:  J Nucl Med       Date:  2017-04-27       Impact factor: 10.057

4.  Design and evaluation of the MAMMI dedicated breast PET.

Authors:  L Moliner; A J Gonzalez; A Soriano; F Sanchez; C Correcher; A Orero; M Carles; L F Vidal; J Barbera; L Caballero; M Seimetz; C Vazquez; J M Benlloch
Journal:  Med Phys       Date:  2012-09       Impact factor: 4.071

5.  Experimental time resolution limits of modern SiPMs and TOF-PET detectors exploring different scintillators and Cherenkov emission.

Authors:  Stefan Gundacker; Rosana Martinez Turtos; Nicolaus Kratochwil; Rosalinde Hendrika Pots; Marco Paganoni; Paul Lecoq; Etiennette Auffray
Journal:  Phys Med Biol       Date:  2020-01-17       Impact factor: 3.609

6.  Roadmap toward the 10 ps time-of-flight PET challenge.

Authors:  Paul Lecoq; Christian Morel; John O Prior; Dimitris Visvikis; Stefan Gundacker; Etiennette Auffray; Peter Križan; Rosana Martinez Turtos; Dominique Thers; Edoardo Charbon; Joao Varela; Christophe de La Taille; Angelo Rivetti; Dominique Breton; Jean-François Pratte; Johan Nuyts; Suleman Surti; Stefaan Vandenberghe; Paul Marsden; Katia Parodi; Jose Maria Benlloch; Mathieu Benoit
Journal:  Phys Med Biol       Date:  2020-10-22       Impact factor: 3.609

7.  Mini EXPLORER II: a prototype high-sensitivity PET/CT scanner for companion animal whole body and human brain scanning.

Authors:  Yang Lv; Xinyu Lv; Weiping Liu; Martin S Judenhofer; Allison Zwingenberger; Erik Wisner; Eric Berg; Sarah McKenney; Edwin Leung; Benjamin A Spencer; Simon R Cherry; Ramsey D Badawi
Journal:  Phys Med Biol       Date:  2019-03-21       Impact factor: 3.609

8.  Performance characteristics of the digital uMI550 PET/CT system according to the NEMA NU2-2018 standard.

Authors:  Shuguang Chen; Pengcheng Hu; Yushen Gu; Haojun Yu; Hongcheng Shi
Journal:  EJNMMI Phys       Date:  2020-06-26

9.  PennPET Explorer: Design and Preliminary Performance of a Whole-Body Imager.

Authors:  Joel S Karp; Varsha Viswanath; Michael J Geagan; Gerd Muehllehner; Austin R Pantel; Michael J Parma; Amy E Perkins; Jeffrey P Schmall; Matthew E Werner; Margaret E Daube-Witherspoon
Journal:  J Nucl Med       Date:  2019-06-21       Impact factor: 11.082

10.  Exploring TOF capabilities of PET detector blocks based on large monolithic crystals and analog SiPMs.

Authors:  Efthymios Lamprou; Antonio J Gonzalez; Filomeno Sanchez; Jose M Benlloch
Journal:  Phys Med       Date:  2020-01-11       Impact factor: 2.685
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  9 in total

Review 1.  Photon counting detectors and their applications ranging from particle physics experiments to environmental radiation monitoring and medical imaging.

Authors:  Ryosuke Ota
Journal:  Radiol Phys Technol       Date:  2021-03-19

2.  New standards for phantom image quality and SUV harmonization range for multicenter oncology PET studies.

Authors:  Go Akamatsu; Naoki Shimada; Keiichi Matsumoto; Hiromitsu Daisaki; Kazufumi Suzuki; Hiroshi Watabe; Keiichi Oda; Michio Senda; Takashi Terauchi; Ukihide Tateishi
Journal:  Ann Nucl Med       Date:  2022-01-14       Impact factor: 2.668

Review 3.  Advances in Detector Instrumentation for PET.

Authors:  Andrea Gonzalez-Montoro; Muhammad Nasir Ullah; Craig S Levin
Journal:  J Nucl Med       Date:  2022-08       Impact factor: 11.082

4.  Performance evaluation of dedicated brain PET scanner with motion correction system.

Authors:  Yuya Onishi; Takashi Isobe; Masanori Ito; Fumio Hashimoto; Tomohide Omura; Etsuji Yoshikawa
Journal:  Ann Nucl Med       Date:  2022-06-13       Impact factor: 2.258

Review 5.  Influences on PET Quantification and Interpretation.

Authors:  Julian M M Rogasch; Frank Hofheinz; Lutz van Heek; Conrad-Amadeus Voltin; Ronald Boellaard; Carsten Kobe
Journal:  Diagnostics (Basel)       Date:  2022-02-10

6.  The role of activity, scan duration and patient's body mass index in the optimization of FDG imaging protocols on a TOF-PET/CT scanner.

Authors:  Roberta Matheoud; Naema Al-Maymani; Alessia Oldani; Gian Mauro Sacchetti; Marco Brambilla; Alessandro Carriero
Journal:  EJNMMI Phys       Date:  2021-04-06

7.  Moving the goalposts while scoring-the dilemma posed by new PET technologies.

Authors:  Julian M M Rogasch; Ronald Boellaard; Lucy Pike; Peter Borchmann; Peter Johnson; Jürgen Wolf; Sally F Barrington; Carsten Kobe
Journal:  Eur J Nucl Med Mol Imaging       Date:  2021-05-14       Impact factor: 9.236

8.  High resolution detectors for whole-body PET scanners by using dual-ended readout.

Authors:  Zheng Liu; Ming Niu; Zhonghua Kuang; Ning Ren; San Wu; Longhan Cong; Xiaohui Wang; Ziru Sang; Crispin Williams; Yongfeng Yang
Journal:  EJNMMI Phys       Date:  2022-04-21

9.  Deep learning-based time-of-flight (ToF) image enhancement of non-ToF PET scans.

Authors:  Abolfazl Mehranian; Scott D Wollenweber; Matthew D Walker; Kevin M Bradley; Patrick A Fielding; Martin Huellner; Fotis Kotasidis; Kuan-Hao Su; Robert Johnsen; Floris P Jansen; Daniel R McGowan
Journal:  Eur J Nucl Med Mol Imaging       Date:  2022-05-04       Impact factor: 10.057
  9 in total

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