| Literature DB >> 33194541 |
Sonia Gupta1, Manveen Kaur Jawanda2, G S Madhushankari3.
Abstract
Oral cancer is one of the common cancers in the world causing high morbidity. Development of cancer is preceded by certain asymptomatic clinical lesions and conditions all together known as 'oral potentially malignant disorders'. Histologically they are represented by the term 'oral epithelial dysplasia'. The degree of severity of dysplasia is determined in the form of 'grade'. Despite the existence of several grading systems proposed by various scholars, it is still a challenging task for the Pathologists to grade dysplasia accurately for the proper diagnosis of the disease and to follow preferable treatment plans. This review aims to focus on the current challenges and the diagnostic pitfalls in the grading of oral epithelial dysplasia in various oral potentially malignant disorders.Entities:
Keywords: CIN, Cervical Intraepithelial Neoplasia; CIS, Carcinoma in situ; Challenge; EAI, Epithelial atypia index; ED, Epithelial dysplasia; ELP, Erythroleukoplakia; EP, Erythroplakia; Epithelial dysplasia; Grade; HPV, Human Papilloma Virus; JSOP, Japanese Society for Oral Pathology; LP, Leukoplakia; N:C, Nuclear cytoplasmic ratio; OED, Oral epithelial dysplasia; OIN, Oral intraepithelial neoplasia; OLP, Oral lichen planus; OPMDs, Oral potentially malignant disorders; OSCC, Oral squamous cell carcinoma; OSMF, Oral submucous fibrosis; Oral; Potentially malignant; SIL, Squamous intraepithelial lesions; SIN, Squamous intraepithelial neoplasia; WHO, World health organization
Year: 2020 PMID： 33194541 PMCID： PMC7645057 DOI： 10.1016/j.jobcr.2020.09.005
Source DB: PubMed Journal: J Oral Biol Craniofac Res ISSN： 2212-4268