Literature DB >> 33180732

MagNI: A Magnetoelectrically Powered and Controlled Wireless Neurostimulating Implant.

Zhanghao Yu, Joshua C Chen, Fatima T Alrashdan, Benjamin W Avants, Yan He, Amanda Singer, Jacob T Robinson, Kaiyuan Yang.   

Abstract

This paper presents the first wireless and programmable neural stimulator leveraging magnetoelectric (ME) effects for power and data transfer. Thanks to low tissue absorption, low misalignment sensitivity and high power transfer efficiency, the ME effect enables safe delivery of high power levels (a few milliwatts) at low resonant frequencies (  ∼ 250 kHz) to mm-sized implants deep inside the body (30-mm depth). The presented MagNI (Magnetoelectric Neural Implant) consists of a 1.5-mm 2 180-nm CMOS chip, an in-house built 4 × 2 mm ME film, an energy storage capacitor, and on-board electrodes on a flexible polyimide substrate with a total volume of 8.2 mm 3. The chip with a power consumption of 23.7  μW includes robust system control and data recovery mechanisms under source amplitude variations (1-V variation tolerance). The system delivers fully-programmable bi-phasic current-controlled stimulation with patterns covering 0.05-to-1.5-mA amplitude, 64-to-512- μs pulse width, and 0-to-200-Hz repetition frequency for neurostimulation.

Entities:  

Mesh:

Year:  2020        PMID: 33180732      PMCID: PMC8712272          DOI: 10.1109/TBCAS.2020.3037862

Source DB:  PubMed          Journal:  IEEE Trans Biomed Circuits Syst        ISSN: 1932-4545            Impact factor:   3.833


  26 in total

1.  Implantable microstimulator: magnetic resonance safety at 1.5 Tesla.

Authors:  Frank G Shellock; Gregoire Cosendai; Sung-Min Park; John A Nyenhuis
Journal:  Invest Radiol       Date:  2004-10       Impact factor: 6.016

Review 2.  Neural stimulation and recording electrodes.

Authors:  Stuart F Cogan
Journal:  Annu Rev Biomed Eng       Date:  2008       Impact factor: 9.590

3.  Wireless magnetothermal deep brain stimulation.

Authors:  Ritchie Chen; Gabriela Romero; Michael G Christiansen; Alan Mohr; Polina Anikeeva
Journal:  Science       Date:  2015-03-12       Impact factor: 47.728

4.  Wireless Recording in the Peripheral Nervous System with Ultrasonic Neural Dust.

Authors:  Dongjin Seo; Ryan M Neely; Konlin Shen; Utkarsh Singhal; Elad Alon; Jan M Rabaey; Jose M Carmena; Michel M Maharbiz
Journal:  Neuron       Date:  2016-08-03       Impact factor: 17.173

5.  A mm-Sized Wireless Implantable Device for Electrical Stimulation of Peripheral Nerves.

Authors:  Jayant Charthad; Ting Chia Chang; Zhaokai Liu; Ahmed Sawaby; Marcus J Weber; Sam Baker; Felicity Gore; Stephen A Felt; Amin Arbabian
Journal:  IEEE Trans Biomed Circuits Syst       Date:  2018-04       Impact factor: 3.833

6.  Wireless, battery-free subdermally implantable photometry systems for chronic recording of neural dynamics.

Authors:  Alex Burton; Sofian N Obaid; Abraham Vázquez-Guardado; Matthew B Schmit; Tucker Stuart; Le Cai; Zhiyuan Chen; Irawati Kandela; Chad R Haney; Emily A Waters; Haijiang Cai; John A Rogers; Luyao Lu; Philipp Gutruf
Journal:  Proc Natl Acad Sci U S A       Date:  2020-01-23       Impact factor: 11.205

7.  Wirelessly powered, fully internal optogenetics for brain, spinal and peripheral circuits in mice.

Authors:  Kate L Montgomery; Alexander J Yeh; John S Ho; Vivien Tsao; Shrivats Mohan Iyer; Logan Grosenick; Emily A Ferenczi; Yuji Tanabe; Karl Deisseroth; Scott L Delp; Ada S Y Poon
Journal:  Nat Methods       Date:  2015-08-17       Impact factor: 28.547

8.  A 176-Channel 0.5cm3 0.7g Wireless Implant for Motor Function Recovery after Spinal Cord Injury.

Authors:  Yi-Kai Lo; Chih-Wei Chang; Yen-Cheng Kuan; Stanislav Culaclii; Brian Kim; Kuanfu Chen; Parag Gad; V Reggie Edgerton; Wentai Liu
Journal:  Dig Tech Pap IEEE Int Solid State Circuits Conf       Date:  2016-02-25

9.  A 250 μm × 57 μm Microscale Opto-electronically Transduced Electrodes (MOTEs) for Neural Recording.

Authors:  Sunwoo Lee; Alejandro Javier Cortese; Aasta Parin Gandhi; Elizabeth Rose Agger; Paul L McEuen; Alyosha Christopher Molnar
Journal:  IEEE Trans Biomed Circuits Syst       Date:  2018-10-15       Impact factor: 3.833

10.  A Sub-millimeter, Inductively Powered Neural Stimulator.

Authors:  Daniel K Freeman; Jonathan M O'Brien; Parshant Kumar; Brian Daniels; Reed A Irion; Louis Shraytah; Brett K Ingersoll; Andrew P Magyar; Andrew Czarnecki; Jesse Wheeler; Jonathan R Coppeta; Michael P Abban; Ronald Gatzke; Shelley I Fried; Seung Woo Lee; Amy E Duwel; Jonathan J Bernstein; Alik S Widge; Ana Hernandez-Reynoso; Aswini Kanneganti; Mario I Romero-Ortega; Stuart F Cogan
Journal:  Front Neurosci       Date:  2017-11-27       Impact factor: 4.677

View more
  4 in total

1.  Nanotechnology Enables Novel Modalities for Neuromodulation.

Authors:  Xiao Yang; Eve McGlynn; Rupam Das; Sergiu P Paşca; Bianxiao Cui; Hadi Heidari
Journal:  Adv Mater       Date:  2021-10-19       Impact factor: 30.849

Review 2.  Wireless Power Delivery Techniques for Miniature Implantable Bioelectronics.

Authors:  Amanda Singer; Jacob T Robinson
Journal:  Adv Healthc Mater       Date:  2021-06-10       Impact factor: 11.092

3.  Wearable wireless power systems for 'ME-BIT' magnetoelectric-powered bio implants.

Authors:  Fatima T Alrashdan; Joshua C Chen; Amanda Singer; Benjamin W Avants; Kaiyuan Yang; Jacob T Robinson
Journal:  J Neural Eng       Date:  2021-07-26       Impact factor: 5.043

4.  A wireless millimetric magnetoelectric implant for the endovascular stimulation of peripheral nerves.

Authors:  Joshua C Chen; Peter Kan; Zhanghao Yu; Fatima Alrashdan; Roberto Garcia; Amanda Singer; C S Edwin Lai; Ben Avants; Scott Crosby; Zhongxi Li; Boshuo Wang; Michelle M Felicella; Ariadna Robledo; Angel V Peterchev; Stefan M Goetz; Jeffrey D Hartgerink; Sunil A Sheth; Kaiyuan Yang; Jacob T Robinson
Journal:  Nat Biomed Eng       Date:  2022-03-31       Impact factor: 29.234

  4 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.