Literature DB >> 3313007

Changes in repeat number, sequence, and reading frame in S-antigen genes of Plasmodium falciparum.

R B Saint1, R L Coppel, A F Cowman, G V Brown, P T Shi, N Barzaga, D J Kemp, R F Anders.   

Abstract

The S antigens from different isolates of Plasmodium falciparum exhibit extensive size, charge, and serological diversity. We show here that the S-antigen genes behave as multiple alleles of a single locus. The size heterogeneity results from different numbers, lengths, and/or sequences of tandem repeat units encoded within the S-antigen genes. Two genes studied here encode antigenically different S antigens but nevertheless have closely related tandem repeat sequences. We show that antigenic differences can arise because repeats are translated in different reading frames.

Entities:  

Mesh：

Substances：

Year:  1987        PMID： 3313007      PMCID： PMC367916          DOI： 10.1128/mcb.7.8.2968-2973.1987

Source DB:  PubMed          Journal:  Mol Cell Biol        ISSN： 0270-7306            Impact factor:   4.272


  19 in total

1.  SOLID-PHASE PEPTIDE SYNTHESES.

Authors:  R B MERRIFIELD
Journal:  Endeavour       Date:  1965-01       Impact factor: 0.444

2.  Screening lambdagt recombinant clones by hybridization to single plaques in situ.

Authors:  W D Benton; R W Davis
Journal:  Science       Date:  1977-04-08       Impact factor: 47.728

3.  Antigens associated with Plasmodium falciparum infections in man.

Authors:  R J Wilson; I A McGregor; P Hall; K Williams; R Bartholomew
Journal:  Lancet       Date:  1969-07-26       Impact factor: 79.321

4.  Efficient isolation of genes by using antibody probes.

Authors:  R A Young; R W Davis
Journal:  Proc Natl Acad Sci U S A       Date:  1983-03       Impact factor: 11.205

5.  A new pair of M13 vectors for selecting either DNA strand of double-digest restriction fragments.

Authors:  J Messing; J Vieira
Journal:  Gene       Date:  1982-10       Impact factor: 3.688

Review 6.  Somatic generation of antibody diversity.

Authors:  S Tonegawa
Journal:  Nature       Date:  1983-04-14       Impact factor: 49.962

Review 7.  Molecular basis for trypanosome antigenic variation.

Authors:  P Borst; G A Cross
Journal:  Cell       Date:  1982-06       Impact factor: 41.582

8.  Occurrence of S-antigens in serum in Plasmodium falciparum infections in man.

Authors:  R J Wilson; I A McGregor; K Williams
Journal:  Trans R Soc Trop Med Hyg       Date:  1975       Impact factor: 2.184

9.  Human malaria parasites in continuous culture.

Authors:  W Trager; J B Jensen
Journal:  Science       Date:  1976-08-20       Impact factor: 47.728

10.  DNA sequencing with chain-terminating inhibitors.

Authors:  F Sanger; S Nicklen; A R Coulson
Journal:  Proc Natl Acad Sci U S A       Date:  1977-12       Impact factor: 11.205
View more
  10 in total

1.  Detection of latent sequence periodicities.

Authors:  E Pizzi; S Liuni; C Frontali
Journal:  Nucleic Acids Res       Date:  1990-07-11       Impact factor: 16.971

Review 2.  Future potential of malaria vaccines.

Authors:  M Hommel
Journal:  J R Soc Med       Date:  1989       Impact factor: 5.344

3.  Third form of the precursor to the major merozoite surface antigens of Plasmodium falciparum.

Authors:  M G Peterson; R L Coppel; M B Moloney; D J Kemp
Journal:  Mol Cell Biol       Date:  1988-06       Impact factor: 4.272

4.  NSR-seq transcriptional profiling enables identification of a gene signature of Plasmodium falciparum parasites infecting children.

Authors:  Marissa Vignali; Christopher D Armour; Jingyang Chen; Robert Morrison; John C Castle; Matthew C Biery; Heather Bouzek; Wonjong Moon; Tomas Babak; Michal Fried; Christopher K Raymond; Patrick E Duffy
Journal:  J Clin Invest       Date:  2011-02-07       Impact factor: 14.808

5.  Structural diversity in the Plasmodium falciparum merozoite surface antigen 2.

Authors:  J A Smythe; R L Coppel; K P Day; R K Martin; A M Oduola; D J Kemp; R F Anders
Journal:  Proc Natl Acad Sci U S A       Date:  1991-03-01       Impact factor: 11.205

6.  Variation of tandem repeats in the developmentally regulated procyclic acidic repetitive proteins of Trypanosoma brucei.

Authors:  M R Mowatt; G S Wisdom; C E Clayton
Journal:  Mol Cell Biol       Date:  1989-03       Impact factor: 4.272

Review 7.  Genome plasticity in Plasmodium.

Authors:  C Frontali
Journal:  Genetica       Date:  1994       Impact factor: 1.082

8.  Plasmodium falciparum merozoite surface protein 2 is unstructured and forms amyloid-like fibrils.

Authors:  Christopher G Adda; Vince J Murphy; Margaret Sunde; Lynne J Waddington; Jesse Schloegel; Gert H Talbo; Kleo Vingas; Vivian Kienzle; Rosella Masciantonio; Geoffrey J Howlett; Anthony N Hodder; Michael Foley; Robin F Anders
Journal:  Mol Biochem Parasitol       Date:  2009-04-09       Impact factor: 1.759

9.  Immune Modulation and Prevention of Autoimmune Disease by Repeated Sequences from Parasites Linked to Self Antigens.

Authors:  Fabiola Puentes; Katharina Dickhaut; Maria Hofstätter; Jennifer Pfeil; Uta Lauer; Alf Hamann; Ute Hoffmann; Kirsten Falk; Olaf Rötzschke
Journal:  J Neuroimmune Pharmacol       Date:  2016-08-12       Impact factor: 4.147

10.  Functional Comparison of Blood-Stage Plasmodium falciparum Malaria Vaccine Candidate Antigens.

Authors:  Joseph J Illingworth; Daniel G Alanine; Rebecca Brown; Jennifer M Marshall; Helen E Bartlett; Sarah E Silk; Geneviève M Labbé; Doris Quinkert; Jee Sun Cho; Jason P Wendler; David J Pattinson; Lea Barfod; Alexander D Douglas; Michael W Shea; Katherine E Wright; Simone C de Cassan; Matthew K Higgins; Simon J Draper
Journal:  Front Immunol       Date:  2019-06-04       Impact factor: 7.561
  10 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.