Literature DB >> 3043189

Third form of the precursor to the major merozoite surface antigens of Plasmodium falciparum.

M G Peterson1, R L Coppel, M B Moloney, D J Kemp.   

Abstract

The precursor to the major merozoite surface antigens of Plasmodium falciparum appears to be encoded by two distinctly different (dimorphic) alleles able to undergo limited recombination. We analyzed 18 previously uncharacterized P. falciparum isolates to test the dimorphic model. All but one, a Thailand isolate, conformed to the dimorphic model, and this isolate conformed to the dimorphic model in all but variable block 2. Sequence analysis revealed that block 2 of isolate CSL2 was a third form. Hence, the dimorphic model is not strictly correct. Recombination between alleles was found only within two conserved blocks near the 5' end of the gene.

Entities:  

Mesh：

Substances：

Year:  1988        PMID： 3043189      PMCID： PMC363471          DOI： 10.1128/mcb.8.6.2664-2667.1988

Source DB:  PubMed          Journal:  Mol Cell Biol        ISSN： 0270-7306            Impact factor:   4.272


  12 in total

1.  Allelic dimorphism in a surface antigen gene of the malaria parasite Plasmodium falciparum.

Authors:  K Tanabe; M Mackay; M Goman; J G Scaife
Journal:  J Mol Biol       Date:  1987-05-20       Impact factor: 5.469

2.  Variation in the precursor to the major merozoite surface antigens of Plasmodium falciparum.

Authors:  M G Peterson; R L Coppel; P McIntyre; C J Langford; G Woodrow; G V Brown; R F Anders; D J Kemp
Journal:  Mol Biochem Parasitol       Date:  1988-01-15       Impact factor: 1.759

3.  Variation in the gene encoding a major merozoite surface antigen of the human malaria parasite Plasmodium falciparum.

Authors:  J L Weber; W M Leininger; J A Lyon
Journal:  Nucleic Acids Res       Date:  1986-04-25       Impact factor: 16.971

4.  Genetic analysis of the human malaria parasite Plasmodium falciparum.

Authors:  D Walliker; I A Quakyi; T E Wellems; T F McCutchan; A Szarfman; W T London; L M Corcoran; T R Burkot; R Carter
Journal:  Science       Date:  1987-06-26       Impact factor: 47.728

5.  Primary structure of the precursor to the three major surface antigens of Plasmodium falciparum merozoites.

Authors:  A A Holder; M J Lockyer; K G Odink; J S Sandhu; V Riveros-Moreno; S C Nicholls; Y Hillman; L S Davey; M L Tizard; R T Schwarz
Journal:  Nature       Date:  1985 Sep 19-25       Impact factor: 49.962

6.  Antigens of the erythrocytes stages of the human malaria parasite Plasmodium falciparum detected by monoclonal antibodies.

Authors:  R Hall; J McBride; G Morgan; A Tait; J W Zolg; D Walliker; J Scaife
Journal:  Mol Biochem Parasitol       Date:  1983-03       Impact factor: 1.759

7.  Polymorphism of the precursor for the major surface antigens of Plasmodium falciparum merozoites: studies at the genetic level.

Authors:  M Mackay; M Goman; N Bone; J E Hyde; J Scaife; U Certa; H Stunnenberg; H Bujard
Journal:  EMBO J       Date:  1985-12-30       Impact factor: 11.598

8.  A naturally occurring gene encoding the major surface antigen precursor p190 of Plasmodium falciparum lacks tripeptide repeats.

Authors:  U Certa; D Rotmann; H Matile; R Reber-Liske
Journal:  EMBO J       Date:  1987-12-20       Impact factor: 11.598

9.  Polymorphism of a high molecular weight schizont antigen of the human malaria parasite Plasmodium falciparum.

Authors:  J S McBride; C I Newbold; R Anand
Journal:  J Exp Med       Date:  1985-01-01       Impact factor: 14.307

10.  Biosynthesis and processing of a Plasmodium falciparum schizont antigen recognized by immune serum and a monoclonal antibody.

Authors:  A A Holder; R R Freeman
Journal:  J Exp Med       Date:  1982-11-01       Impact factor: 14.307
View more
  12 in total

1.  Roles of conserved and allelic regions of the major merozoite surface protein (gp195) in immunity against Plasmodium falciparum.

Authors:  G S Hui; A Hashimoto; S P Chang
Journal:  Infect Immun       Date:  1992-04       Impact factor: 3.441

2.  Structural and antigenic polymorphism of the 35- to 48-kilodalton merozoite surface antigen (MSA-2) of the malaria parasite Plasmodium falciparum.

Authors:  B Fenton; J T Clark; C M Khan; J V Robinson; D Walliker; R Ridley; J G Scaife; J S McBride
Journal:  Mol Cell Biol       Date:  1991-02       Impact factor: 4.272

3.  Immunological cross-reactivity of the C-terminal 42-kilodalton fragment of Plasmodium falciparum merozoite surface protein 1 expressed in baculovirus.

Authors:  G S Hui; C Hashiro; C Nikaido; S E Case; A Hashimoto; H Gibson; P J Barr; S P Chang
Journal:  Infect Immun       Date:  1993-08       Impact factor: 3.441

4.  A protective monoclonal antibody recognizes a linear epitope in the precursor to the major merozoite antigens of Plasmodium chabaudi adami.

Authors:  A M Lew; C J Langford; R F Anders; D J Kemp; A Saul; C Fardoulys; M Geysen; M Sheppard
Journal:  Proc Natl Acad Sci U S A       Date:  1989-05       Impact factor: 11.205

5.  Human antibody response to the major merozoite surface antigen of Plasmodium falciparum is strain specific and short-lived.

Authors:  K Früh; O Doumbo; H M Müller; O Koita; J McBride; A Crisanti; Y Touré; H Bujard
Journal:  Infect Immun       Date:  1991-04       Impact factor: 3.441

6.  Structural diversity in the Plasmodium falciparum merozoite surface antigen 2.

Authors:  J A Smythe; R L Coppel; K P Day; R K Martin; A M Oduola; D J Kemp; R F Anders
Journal:  Proc Natl Acad Sci U S A       Date:  1991-03-01       Impact factor: 11.205

7.  Characterization of human T- and B-cell epitopes in the C terminus of Plasmodium falciparum merozoite surface protein 1: evidence for poor T-cell recognition of polypeptides with numerous disulfide bonds.

Authors:  A Egan; M Waterfall; M Pinder; A Holder; E Riley
Journal:  Infect Immun       Date:  1997-08       Impact factor: 3.441

8.  Regulated maturation of malaria merozoite surface protein-1 is essential for parasite growth.

Authors:  Matthew A Child; Christian Epp; Hermann Bujard; Michael J Blackman
Journal:  Mol Microbiol       Date:  2010-02-08       Impact factor: 3.501

9.  A prospective study of the association between the human humoral immune response to Plasmodium falciparum blood stage antigen gp190 and control of malarial infections.

Authors:  R Tolle; K Früh; O Doumbo; O Koita; M N'Diaye; A Fischer; K Dietz; H Bujard
Journal:  Infect Immun       Date:  1993-01       Impact factor: 3.441

10.  Dominance of conserved B-cell epitopes of the Plasmodium falciparum merozoite surface protein, MSP1, in blood-stage infections of naive Aotus monkeys.

Authors:  G S Hui; C Nikaido; C Hashiro; D C Kaslow; W E Collins
Journal:  Infect Immun       Date:  1996-05       Impact factor: 3.441
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.