| Literature DB >> 33105403 |
Brittany S Hollerbach1, Kevin C Mathias, Donald Stewart, Kepra Jack, Denise L Smith.
Abstract
OBJECTIVE: Examine atherosclerotic cardiovascular disease (ASCVD) risk scores by age and weight status in career firefighters.Entities:
Mesh:
Year: 2020 PMID: 33105403 PMCID: PMC7720876 DOI: 10.1097/JOM.0000000000002057
Source DB: PubMed Journal: J Occup Environ Med ISSN: 1076-2752 Impact factor: 2.306
Descriptive Statistics of a US Firefighter Cohort by Age Category
| Age Category, yr | ||||
| Total | 40–44 | 45–49 | 50+ | |
| 644 (100) | 241 (37) | 191 (30) | 212 (33) | |
| Age, yr | 47.7 ± 5.2 | 42.6 ± 1.7 | 47.4 ± 1.1 | 53.8 ± 3.1 |
| Male | 591 (92) | 216 (89) | 178 (93) | 197 (93) |
| White | 504 (78) | 183 (76) | 154 (81) | 167 (79) |
| African American/Black | 84 (13) | 31 (13) | 23 (12) | 30 (14) |
| Other | 56 (8) | 27 (11) | 14 (7) | 15 (7) |
| Height, m | 1.8 ± 0.1 | 1.8 ± 0.1 | 1.8 ± 0.1 | 1.8 ± 0.1 |
| Weight, kg | 92.4 ± 15.2 | 92.0 ± 15.3 | 93.1 ± 15.3 | 92.1 ± 15.0 |
| Body mass index, kg/m2 | 29.2 ± 4.0 | 29.1 ± 4.1 | 29.5 ± 3.9 | 29.0 ± 4.0 |
| Normal | 87 (14) | 36 (15) | 21 (11) | 30 (14) |
| Overweight | 303 (47) | 111 (46) | 89 (47) | 103 (49) |
| Obese | 254 (39) | 94 (39) | 81 (42) | 79 (37) |
| Pooled cohort risk score (%)∗ | 3.7 ± 3.4 | 1.8 ± 1.3 | 3.5 ± 2.5 | 6.2 ± 4.1 |
| <5% | 494 (77) | 232 (96) | 164 (86) | 98 (46) |
| ≥5%–7.5% | 91 (14) | 9 (4) | 18 (9) | 64 (30) |
| ≥7.5%–20% | 54 (8) | 0 (0) | 9 (5) | 45 (21) |
| ≥20% | 5 (1) | 0 (0) | 0 (0) | 5 (2) |
Values are means ± SD or n (%).
10-year ASCVD risk based on PC algorithm published in 2013 ACC/AHA Guideline on the Assessment of Cardiovascular Risk.
10-Year Risk of ASCVD Among a Cohort of US Firefighters by Age Category
| Percentiles (10-year Risk of ASCVD) | |||||||||
| Age Category | 5th | 10th | 25th | 50th | 75th | 90th | 95th | Mean (95% CI) | |
| 40–44, yrs | 0.4 | 0.6 | 1.0 | 1.5 | 2.4 | 3.4 | 4.5 | 1.8 (1.7–2.0) | |
| 45–49, yrs | 0.8 | 1.3 | 2.0 | 3.0 | 4.2 | 5.6 | 7.2 | 3.5 (3.1–3.8) | <0.001 |
| ≥50, yrs | 2.0 | 2.5 | 3.6 | 5.2 | 7.1 | 10.5 | 15.0 | 6.2 (5.6–6.7) | |
ASCVD, atherosclerotic cardiovascular disease.
The trend was tested using a simple linear regression model with age categories modeled as a continuous variable.
10-Year Risk of ASCVD Among a Cohort of US Firefighters by BMI Category
| Percentiles (10-year Risk of ASCVD) | |||||||||
| BMI Category† | 5th | 10th | 25th | 50th | 75th | 90th | 95th | Mean (95% CI) | |
| Normal | 0.2 | 0.3 | 0.6 | 1.4 | 3.4 | 5.3 | 6.2 | 2.2 (1.7–2.7) | |
| Overweight | 0.7 | 0.9 | 1.6 | 2.6 | 4.3 | 6.1 | 8.4 | 3.3 (3.0–3.6) | <0.001 |
| Obese | 1.0 | 1.2 | 2.2 | 3.6 | 5.8 | 10.1 | 12.8 | 4.8 (4.3–5.2) | |
ASCVD, atherosclerotic cardiovascular disease; BMI, body mass index.
The trend was tested using a simple linear regression model with BMI categories modeled as a continuous variable.
BMI categories were defined as normal (less than 25 kg/m2), overweight (more than or equal to 25 kg/m2 to less than 30 kg/m2), and obese (more than or equal to 30 kg/m2).
FIGURE 1Percentages of firefighters within categories of ASCVD risk by body mass index (BMI) categories. Error bars represent 95% confidence intervals. BMI categories were defined as normal (less than 25 kg/m2), overweight (more than or equal to 25 to less than 30 kg/m2), and obese (more than or equal to 30 kg/m2). ASCVD, atherosclerotic cardiovascular disease.
FIGURE 210-year risk of ASCVD by age and BMI categories. Error bars represent 95% confidence intervals. A linear regression model including age, BMI, and an interaction term was conducted, and all terms were significant (P < 0.05). The three age categories and three BMI categories were modeled as continuous variables. Age is represented in years. BMI categories were defined as normal (less than 25 kg/m2), overweight (more than or equal to 25 kg/m2 to less than 30 kg/m2), and obese (more than or equal to 30 kg/m2). The means and 95% confidence intervals reported are descriptive. ASCVD, atherosclerotic cardiovascular disease; BMI, body mass index.
FIGURE 3Percentages of firefighters within categories of 10-year ASCVD risk by age categories and BMI categories. Age is represented in years. BMI categories were defined as normal (less than 25 kg/m2), overweight (more than or equal to 25 kg/m2 to less than 30 kg/m2), and obese (more than or equal to 30 kg/m2). An order logit model including age, BMI, and an interaction term was conducted and all terms were significant (P < 0.05). The three age categories and three BMI categories were modeled as continuous variables. The percentages reported are descriptive tabulations. ASCVD, atherosclerotic cardiovascular disease; BMI, body mass index.