| Literature DB >> 32366797 |
Kevin C Mathias1, Emilie D Bode1, Donald F Stewart2, Denise L Smith.
Abstract
PURPOSE: This study aimed to assess changes in cardiovascular disease (CVD) risk factors in firefighters who lost, maintained, or gained weight over 5 yr.Entities:
Mesh:
Substances:
Year: 2020 PMID: 32366797 PMCID: PMC7556237 DOI: 10.1249/MSS.0000000000002398
Source DB: PubMed Journal: Med Sci Sports Exerc ISSN: 0195-9131
Descriptive statistics of a U.S. firefighter cohort at baseline by prospective weight change.
| Total Sample | Weight Loss | Weight Stable | Weight Gain | |
|---|---|---|---|---|
| 656 (100) | 81 (12) | 248 (38) | 327 (50) | |
| Age (yr) | 38.1 ± 7.8 | 39.3 ± 9.1 | 39.2 ± 7.3 | 37.0 ± 7.7 |
| Male, | 589 (90) | 71 (88) | 224 (90) | 294 (90) |
| White/other, | 525 (80) | 61 (75) | 202 (81) | 262 (80) |
| African-American, | 131 (20) | 20 (25) | 46 (19) | 65 (20) |
| Duration between exams (yr) | 4.8 ± 0.6 | 4.7 ± 0.6 | 4.8 ± 0.5 | 4.8 ± 0.6 |
| Height (m) | 1.8 ± 0.1 | 1.8 ± 0.1 | 1.8 ± 0.1 | 1.8 ± 0.1 |
| Body weight (kg) | 88.8 ± 14.9 | 95.0 ± 14.8 | 87.7 ± 14.0 | 88.1 ± 15.2 |
| BMI (kg·m−2) | 28.1 ± 3.8 | 29.7 ± 3.9 | 27.9 ± 3.6 | 27.8 ± 4.0 |
| Total cholesterol (mg·dL−1) | 186.1 ± 35.3 | 185.0 ± 35.3 | 190.0 ± 35.6 | 183.3 ± 35.0 |
| LDL cholesterol (mg·dL−1) | 116.5 ± 30.8 | 116.9 ± 29.9 | 119.9 ± 35.6 | 113.7 ± 29.4 |
| HDL cholesterol (mg·dL−1) | 47.5 ± 11.2 | 46.7 ± 11.9 | 47.1 ± 11.6 | 48.2 ± 10.7 |
| Systolic blood pressure (mm Hg) | 121.0 ± 10.9 | 122.5 ± 12.1 | 122.0 ± 10.5 | 119.8 ± 10.8 |
| Diastolic blood pressure (mm Hg) | 79.3 ± 8.8 | 79.8 ± 9.3 | 80.3 ± 8.5 | 78.5 ± 8.8 |
| Blood glucose (mg·dL−1) | 94.1 ± 11.7 | 98.3 ± 19.0 | 93.7 ± 10.4 | 93.2 ± 9.6 |
| 10-yr risk of CVD event (%) | 5.0 ± 3.8 | 6.4 ± 5.3 | 5.4 ± 3.9 | 4.1 ± 2.9 |
Data are presented as n (%) or mean ± SD.
Weight loss subgroup defined as >3% of body weight lost.
Weight stable subgroup defined as within ±3% body weight change (gain or loss).
Weight gain subgroup defined as >3% of body weight gained.
The 10-yr risk of a first CVD event among ≥30 yr olds estimated from risk functions published in 2008 using data from the Framingham Heart Study and the Framingham Offspring Study.
Changes in CVD risk factors in a cohort of U.S. firefighters over 5 yr by weight change category.
| Total Sample | Weight Loss | Weight Stable | Weight Gain | |
|---|---|---|---|---|
| Body weight (kg) | 2.5 ± 0.2*** | −7.2 ± 0.5*** | 0.3 ± 0.1** | 6.6 ± 0.2*** |
| BMI (kg·m−2) | 0.8 ± 0.1*** | −2.2 ± 0.2*** | 0.09 ± 0.04* | 2.1 ± 0.1*** |
| Total cholesterol (mg·dL−1) | 5.5 ± 1.4*** | −8.5 ± 3.9* | 1.4 ± 2.3 | 12.9 ± 1.8*** |
| LDL cholesterol (mg·dL−1) | 5.2 ± 1.2*** | −6.7 ± 3.3* | 2.0 ± 1.9 | 11.1 ± 1.6*** |
| HDL cholesterol (mg·dL−1) | −0.1 ± 0.3 | 2.3 ± 1.0* | 0.5 ± 0.5 | −1.3 ± 0.4** |
| Systolic blood pressure (mm Hg) | −1.3 ± 0.5** | −5.3 ± 1.3*** | −3.5 ± 0.8*** | 1.3 ± 0.7 |
| Diastolic blood pressure (mm Hg) | −2.4 ± 0.4*** | −4.2 ± 1.0*** | −3.7 ± 0.6*** | −0.9 ± 0.6 |
| Blood glucose (mg·dL−1) | 2.1 ± 0.5*** | −2.2 ± 1.2 | 2.7 ± 0.9** | 2.9 ± 0.7*** |
| 10-yr risk of CVD event (%) | 2.0 ± 0.1*** | 0.6 ± 0.3 | 1.7 ± 0.2*** | 2.6 ± 0.2*** |
Data are presented as mean ± SE.
Weight Loss subgroup defined as >3% of body weight lost.
Weight Stable subgroup defined as within ±3% body weight change (gain or loss).
Weight Gain subgroup defined as >3% of body weight gained.
10-yr risk of a first CVD event among ≥30 yr olds estimated from risk functions published in 2008 using data from the Framingham Heart Study and the Framingham Offspring Study.
*P < 0.05.
**P < 0.01.
***P < 0.001.
Percentages with CVD risk factors over a 5-yr period in a cohort of U.S. firefighters by weight change category.
| Total Sample | Weight Loss | Weight Stable | Weight Gain | |||||
|---|---|---|---|---|---|---|---|---|
| Time 1 (%) | Time 2 (%) | Time 1 (%) | Time 2 (%) | Time 1 (%) | Time 2 (%) | Time 1 (%) | Time 2 (%) | |
| Obese | 27 | 36*** | 38 | 20*** | 26 | 29 | 25 | 45*** |
| High cholesterol | 9 | 14** | 6 | 12 | 12 | 12 | 8 | 16** |
| Low HDL | 27 | 27 | 29 | 22 | 31 | 26 | 24 | 30* |
| High blood glucose | 1 | 3* | 6 | 6 | 2 | 2 | 0 | 4** |
| High blood pressure | 56 | 44*** | 59 | 39** | 61 | 42*** | 53 | 48 |
| Antihypertensive medication (%) | 11 | 16*** | 20 | 25 | 11 | 15 | 9 | 16*** |
Weight loss subgroup defined as >3% of body weight lost.
Weight stable subgroup defined as within ±3% body weight change (gain or loss).
Weight gain subgroup defined as >3% of body weight gained.
*P < 0.05.
**P < 0.01.
***P < 0.001.