Literature DB >> 3307706

Mutagenic activity of the feces of rats following oral administration of tartrazine.

R Münzner, J Wever.   

Abstract

After oral administration of the azo dye tartrazine, bile and feces of treated rats were investigated for mutagenicity using the Ames test with Salmonella typhimurium strains TA 98 and TA 100 with and without metabolic activation. In the presence of S 9-mix fecal extracts developed a weak but reproducible dose-related response in strain TA 100. In bile no metabolites exerting mutagenic activity were found.

Entities:  

Mesh:

Substances:

Year:  1987        PMID: 3307706     DOI: 10.1007/BF01234674

Source DB:  PubMed          Journal:  Arch Toxicol        ISSN: 0340-5761            Impact factor:   5.153


  11 in total

1.  THE METABOLISM AND EXCRETION OF TARTRAZINE IN THE RAT, RABBIT AND MAN.

Authors:  R JONES; A J RYAN; S E WRIGHT
Journal:  Food Cosmet Toxicol       Date:  1964-10

2.  The excretion and metabolism of edible food colors.

Authors:  J W DANIEL
Journal:  Toxicol Appl Pharmacol       Date:  1962-09       Impact factor: 4.219

3.  The excretion of some azo dyes in rat bile.

Authors:  A J RYAN; S E WRIGHT
Journal:  J Pharm Pharmacol       Date:  1961-08       Impact factor: 3.765

4.  Methods for detecting carcinogens and mutagens with the Salmonella/mammalian-microsome mutagenicity test.

Authors:  B N Ames; J Mccann; E Yamasaki
Journal:  Mutat Res       Date:  1975-12       Impact factor: 2.433

5.  Mutagenic activity in the stomach and small intestine of rats after oral administration of nitrosated beef extract.

Authors:  R Münzner; J Wever
Journal:  Cancer Lett       Date:  1984-12       Impact factor: 8.679

6.  Tartrazine--a reinvestigation by in vivo cytogenetic methods.

Authors:  H W Renner
Journal:  Food Chem Toxicol       Date:  1984-04       Impact factor: 6.023

7.  Investigations on the detection of mutagenic activity of beef extract in rats after oral administration.

Authors:  R Münzner; J Wever
Journal:  Cancer Lett       Date:  1984-05       Impact factor: 8.679

Review 8.  An evaluation of the host-mediated assay and body fluid analysis. A report of the U.S. Environmental Protection Agency Gene-Tox Program.

Authors:  M S Legator; E Bueding; R Batzinger; T H Connor; E Eisenstadt; M G Farrow; G Ficsor; A Hsie; J Seed; R S Stafford
Journal:  Mutat Res       Date:  1982-05       Impact factor: 2.433

9.  Screening of food dyes for genotoxic activity.

Authors:  R B Haveland-Smith; R D Combes
Journal:  Food Cosmet Toxicol       Date:  1980-06

10.  Tartrazine-induced chromosomal aberrations in mammalian cells.

Authors:  R M Patterson; J S Butler
Journal:  Food Chem Toxicol       Date:  1982-08       Impact factor: 6.023

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.