Literature DB >> 33052078

Increasing the efficiency of mechanical ventilators during pandemics through additive manufacturing.

Abdullatif Alwasel1, Jean Zaky2, Khalid Alhussaini1, Bandr Alossimi1, Turki Alharbi2.   

Abstract

The COVID-19 pandemic tested medical facilities' readiness in terms of the number of available mechanical ventilators. Most countries raced to stock up on ventilators, which created a surge in demand and short in supply. Furthermore, other means of coping with the demand were proposed, such as using additive manufacturing. The purpose of this paper was to test whether the addition of 3D-printed splitters would help deliver required tidal volume to each patient, while supporting four patients on a single ventilator for 24 hours on pressure mode at 25-cm H2O, and to determine whether a fifth patient can be ventilated. The ventilation of four human lungs was simulated using 3D printed parts, a single ventilator, four test-lungs, and standard tubing. Peak pressure, positive end-expiratory pressure, total tidal volume, individual tidal volume, total minute volume, and individual tidal volume data were collected. Usage of a 3D printed small size splitter enabled a 26% increase in individual tidal volume compared to standard tubing and a series of two-way splitters. The ventilator was able to supply the required pressure and tidal volume for 24 hours. A single ventilator with a four-way splitter can ventilate four patients experiencing respiratory failure for at least 24 hours without interruption. The equipment cannot sustain ventilating a fifth patient owing to minute volume limitation. This study expands on an earlier study that tested similar circuitry and reveals that the desired individual tidal volume is achieved. However, further research is required to provide the monitoring ability of individual patient parameters and prevention of cross-contamination.

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Year:  2021        PMID: 33052078      PMCID: PMC7982068          DOI: 10.17305/bjbms.2020.5165

Source DB:  PubMed          Journal:  Bosn J Basic Med Sci        ISSN: 1512-8601            Impact factor:   3.363


  6 in total

1.  Critical Supply Shortages - The Need for Ventilators and Personal Protective Equipment during the Covid-19 Pandemic.

Authors:  Megan L Ranney; Valerie Griffeth; Ashish K Jha
Journal:  N Engl J Med       Date:  2020-03-25       Impact factor: 91.245

2.  3D printed circuit splitter and flow restriction devices for multiple patient lung ventilation using one anaesthesia workstation or ventilator.

Authors:  A L Clarke
Journal:  Anaesthesia       Date:  2020-04-19       Impact factor: 6.955

3.  The value of positive end-expiratory pressure and Fio₂ criteria in the definition of the acute respiratory distress syndrome.

Authors:  Martin Britos; Elizabeth Smoot; Kathleen D Liu; B Taylor Thompson; William Checkley; Roy G Brower
Journal:  Crit Care Med       Date:  2011-09       Impact factor: 7.598

4.  Increasing ventilator surge capacity in disasters: ventilation of four adult-human-sized sheep on a single ventilator with a modified circuit.

Authors:  Lorenzo Paladino; Mark Silverberg; Jean G Charchaflieh; Julie K Eason; Brian J Wright; Nicholas Palamidessi; Bonnie Arquilla; Richard Sinert; Seth Manoach
Journal:  Resuscitation       Date:  2007-12-31       Impact factor: 5.262

5.  Acute Respiratory Distress Syndrome: Diagnosis and Management.

Authors:  Aaron Saguil; Matthew V Fargo
Journal:  Am Fam Physician       Date:  2020-06-15       Impact factor: 3.292

6.  A single ventilator for multiple simulated patients to meet disaster surge.

Authors:  Greg Neyman; Charlene Babcock Irvin
Journal:  Acad Emerg Med       Date:  2006-08-02       Impact factor: 3.451

  6 in total

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