Literature DB >> 329848

Glycopyrrolate-neostigmine mixture for antagonism of neuromuscular block: comparison with atropine-neostigmine mixture.

R K Mirakhur, J W Dundee, R S Clarke.   

Abstract

Glycopyrrolate, a new anticholinergic agent, was evaluated and compared with atropine. Glycopyrrolate 0.2 mg to neostigmine 1.0 mg was found to be safe and effective. The heart rates remained more stable with glycopyrrolate, and the frequency of arrhythmia, which was both transient and of no consequence, was similar in the two groups. The antisialogogue action of glycopyrrolate was superior to that of atropine.

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Year:  1977        PMID： 329848     DOI： 10.1093/bja/49.8.825

Source DB:  PubMed          Journal:  Br J Anaesth        ISSN： 0007-0912            Impact factor:   9.166


  12 in total

1.  Design, pharmacokinetic, and pharmacodynamic evaluation of a new class of soft anticholinergics.

Authors:  Fenglei Huang; Clinton E Browne; Whei-Mei Wu; Attila Juhász; Fubao Ji; Nicholas Bodor
Journal:  Pharm Res       Date:  2003-10       Impact factor: 4.200

Review 2.  A simulation of neuromuscular function and heart rate during induction, maintenance, and reversal of neuromuscular blockade.

Authors:  R R Jaklitsch; D R Westenskow
Journal:  J Clin Monit       Date:  1990-01

Review 3.  Anticholinergic drugs and anaesthesia.

Authors:  R K Mirakhur
Journal:  Can J Anaesth       Date:  1988-09       Impact factor: 5.063

4.  Cholinergic stimulation alters performance and task-specific regional cerebral blood flow during working memory.

Authors:  M L Furey; P Pietrini; J V Haxby; G E Alexander; H C Lee; J VanMeter; C L Grady; U Shetty; S I Rapoport; M B Schapiro; U Freo
Journal:  Proc Natl Acad Sci U S A       Date:  1997-06-10       Impact factor: 11.205

5.  Proceeding of the British Pharmacological Society, Clinical Pharmacology Section, 16-18th December, 1980, University of London. Abstracts.

Authors: 
Journal:  Br J Clin Pharmacol       Date:  1981-04       Impact factor: 4.335

6.  Cardiovascular changes during induction of anaesthesia. Influence of three anticholinergic premedicants.

Authors:  R K Mirakhur; J W Dundee
Journal:  Ann R Coll Surg Engl       Date:  1979-11       Impact factor: 1.891

7.  Comparison of the effects of atropine and glycopyrrolate on various end-organs.

Authors:  R K Mirakhur; J W Dundee
Journal:  J R Soc Med       Date:  1980-10       Impact factor: 5.344

8.  Cholinergic enhancement reduces functional connectivity and BOLD variability in visual extrastriate cortex during selective attention.

Authors:  Emiliano Ricciardi; Giacomo Handjaras; Giulio Bernardi; Pietro Pietrini; Maura L Furey
Journal:  Neuropharmacology       Date:  2012-08-18       Impact factor: 5.250

9.  Atropine or glycopyrrolate with neostigmine 5 mg: a comparative dose-response study.

Authors:  M G Salem; R S Ahearn
Journal:  J R Soc Med       Date:  1986-01       Impact factor: 5.344

10.  Selective effects of cholinergic modulation on task performance during selective attention.

Authors:  Maura L Furey; Pietro Pietrini; James V Haxby; Wayne C Drevets
Journal:  Neuropsychopharmacology       Date:  2007-05-30       Impact factor: 7.853
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