Literature DB >> 32959893

Centromeres: genetic input to calibrate an epigenetic feedback loop.

Sebastiaan Jw van den Berg1,2, Lars Et Jansen1.   

Abstract

Centromeres are chromatin domains maintained by a self-templating feedback loop based on nucleosomes bearing the histone H3 variant CENP-A. The underlying centromeric DNA sequence is largely dispensable, yet paradoxically, it has highly conserved features. Hoffmann et al (2020) now uncover that when the epigenetic chromatin cycle falters, a genetically hardwired mechanism offers robustness to a dynamic epigenetic feedback loop ensuring long-term centromere inheritance.
© 2020 The Authors.

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Year:  2020        PMID： 32959893      PMCID： PMC7560195          DOI： 10.15252/embj.2020106638

Source DB:  PubMed          Journal:  EMBO J        ISSN： 0261-4189            Impact factor:   14.012


  11 in total

1.  The quantitative architecture of centromeric chromatin.

Authors:  Dani L Bodor; João F Mata; Mikhail Sergeev; Ana Filipa David; Kevan J Salimian; Tanya Panchenko; Don W Cleveland; Ben E Black; Jagesh V Shah; Lars Et Jansen
Journal:  Elife       Date:  2014-07-15       Impact factor: 8.140

Review 2.  What are memories made of? How Polycomb and Trithorax proteins mediate epigenetic memory.

Authors:  Philipp A Steffen; Leonie Ringrose
Journal:  Nat Rev Mol Cell Biol       Date:  2014-05       Impact factor: 94.444

3.  Drosophila CENH3 is sufficient for centromere formation.

Authors:  María José Mendiburo; Jan Padeken; Stefanie Fülöp; Aloys Schepers; Patrick Heun
Journal:  Science       Date:  2011-11-04       Impact factor: 47.728

Review 4.  Genetics, epigenetics and back again: Lessons learned from neocentromeres.

Authors:  Marina Murillo-Pineda; Lars E T Jansen
Journal:  Exp Cell Res       Date:  2020-02-14       Impact factor: 3.905

5.  HJURP is a CENP-A chromatin assembly factor sufficient to form a functional de novo kinetochore.

Authors:  Meghan C Barnhart; P Henning J L Kuich; Madison E Stellfox; Jared A Ward; Emily A Bassett; Ben E Black; Daniel R Foltz
Journal:  J Cell Biol       Date:  2011-07-18       Impact factor: 10.539

6.  CENP-B box is required for de novo centromere chromatin assembly on human alphoid DNA.

Authors:  Jun-ichirou Ohzeki; Megumi Nakano; Teruaki Okada; Hiroshi Masumoto
Journal:  J Cell Biol       Date:  2002-12-02       Impact factor: 10.539

7.  Centromeres: genetic input to calibrate an epigenetic feedback loop.

Authors:  Sebastiaan Jw van den Berg; Lars Et Jansen
Journal:  EMBO J       Date:  2020-09-22       Impact factor: 14.012

8.  Reconstituting Drosophila Centromere Identity in Human Cells.

Authors:  Virginie Roure; Bethan Medina-Pritchard; Vasiliki Lazou; Luciano Rago; Eduard Anselm; Daniela Venegas; A Arockia Jeyaprakash; Patrick Heun
Journal:  Cell Rep       Date:  2019-10-08       Impact factor: 9.423

9.  Mechanism of centromere recruitment of the CENP-A chaperone HJURP and its implications for centromere licensing.

Authors:  Dongqing Pan; Kai Walstein; Annika Take; David Bier; Nadine Kaiser; Andrea Musacchio
Journal:  Nat Commun       Date:  2019-09-06       Impact factor: 14.919

10.  A genetic memory initiates the epigenetic loop necessary to preserve centromere position.

Authors:  Helena M Izquierdo; Riccardo Gamba; Sebastian Hoffmann; Florian Chardon; Marie Dumont; Veer Keizer; Solène Hervé; Shannon M McNulty; Beth A Sullivan; Nicolas Manel; Daniele Fachinetti
Journal:  EMBO J       Date:  2020-09-18       Impact factor: 14.012
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  2 in total

1.  Centromeres: genetic input to calibrate an epigenetic feedback loop.

Authors:  Sebastiaan Jw van den Berg; Lars Et Jansen
Journal:  EMBO J       Date:  2020-09-22       Impact factor: 14.012

2.  The Sequence Dependent Nanoscale Structure of CENP-A Nucleosomes.

Authors:  Tommy Stormberg; Yuri L Lyubchenko
Journal:  Int J Mol Sci       Date:  2022-09-27       Impact factor: 6.208
  2 in total

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