Literature DB >> 3295443

Trypanocidal activity of the stearylamine-bearing liposome in vitro.

E Yoshihara, H Tachibana, T Nakae.   

Abstract

Liposome made of stearylamine and phosphatidylcholine showed the trypanocidal activity in vitro. Cytotoxicity of the liposome against Trypanosoma cruzi appeared to be the strongest in trypomastigotes followed by amastigotes and epimastigotes. Lysis of the human erythrocyte was undetectably low under the conditions that the liposome kills more than 95% of trypomastigotes. The liposome seems to damage the plasma membrane.

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Year:  1987        PMID： 3295443     DOI： 10.1016/0024-3205(87)90005-1

Source DB:  PubMed          Journal:  Life Sci        ISSN： 0024-3205            Impact factor:   5.037


  6 in total

1.  In vitro lysis of the bloodstream forms of Trypanosoma brucei gambiense by stearylamine-bearing liposomes.

Authors:  H Tachibana; E Yoshihara; Y Kaneda; T Nakae
Journal:  Antimicrob Agents Chemother       Date:  1988-07       Impact factor: 5.191

2.  Antileishmanial activities of stearylamine-bearing liposomes.

Authors:  T Dey; K Anam; F Afrin; N Ali
Journal:  Antimicrob Agents Chemother       Date:  2000-06       Impact factor: 5.191

3.  Inhibition of the Growth of Plasmodium falciparum in Culture by Stearylamine-Phosphatidylcholine Liposomes.

Authors:  Gulam Mustafa Hasan; Neha Garg; Enna Dogra; Ranu Surolia; Prahlad Chandra Ghosh
Journal:  J Parasitol Res       Date:  2011-06-14

Review 4.  Nano-Medicines a Hope for Chagas Disease!

Authors:  Satabdi Datta Choudhury
Journal:  Front Mol Biosci       Date:  2021-06-01

Review 5.  Therapeutic Interventions for Countering Leishmaniasis and Chagas's Disease: From Traditional Sources to Nanotechnological Systems.

Authors:  Eliana B Souto; João Dias-Ferreira; Sara A Craveiro; Patrícia Severino; Elena Sanchez-Lopez; Maria L Garcia; Amélia M Silva; Selma B Souto; Sheefali Mahant
Journal:  Pathogens       Date:  2019-08-01

Review 6.  Advances in nanocarriers as drug delivery systems in Chagas disease.

Authors:  Christian Quijia Quezada; Clênia S Azevedo; Sébastien Charneau; Jaime M Santana; Marlus Chorilli; Marcella B Carneiro; Izabela Marques Dourado Bastos
Journal:  Int J Nanomedicine       Date:  2019-08-09
  6 in total

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