Literature DB >> 32943808

Automated Raman Spectral Preprocessing of Bone and Other Musculoskeletal Tissues.

Francis W L Esmonde-White1, Matthew V Schulmerich1, Karen A Esmonde-White2, Michael D Morris1.   

Abstract

Raman spectroscopy of bone is complicated by fluorescence background and spectral contributions from other tissues. Full utilization of Raman spectroscopy in bone studies requires rapid and accurate calibration and preprocessing methods. We have taken a step-wise approach to optimize and automate calibrations, preprocessing and background correction. Improvements to manual spike removal, white light correction, software image rotation and slit image curvature correction are described. Our approach is concisely described with a minimum of mathematical detail.

Entities:  

Keywords:  Raman Spectroscopy; background correction; bone; dichroic filter spectra; fluorescence removal; image rotation; musculoskeletal tissue; preprocessing; spike removal

Year:  2009        PMID: 32943808      PMCID: PMC7493803          DOI: 10.1117/12.809436

Source DB:  PubMed          Journal:  Proc SPIE Int Soc Opt Eng        ISSN: 0277-786X


  13 in total

1.  Raman spectroscopic imaging markers for fatigue-related microdamage in bovine bone.

Authors:  J A Timlin; A Carden; M D Morris; R M Rajachar; D H Kohn
Journal:  Anal Chem       Date:  2000-05-15       Impact factor: 6.986

2.  Image curvature correction and cosmic removal for high-throughput dispersive Raman spectroscopy.

Authors:  Jun Zhao
Journal:  Appl Spectrosc       Date:  2003-11       Impact factor: 2.388

3.  Band-target entropy minimization. A robust algorithm for pure component spectral recovery. Application to complex randomized mixtures of six components.

Authors:  Effendi Widjaja; Chuanzhao Li; Wee Chew; Marc Garland
Journal:  Anal Chem       Date:  2003-09-01       Impact factor: 6.986

4.  Real-time Raman system for in vivo disease diagnosis.

Authors:  Jason T Motz; Saumil J Gandhi; Obrad R Scepanovic; Abigail S Haka; John R Kramer; Ramachandra R Dasari; Michael S Feld
Journal:  J Biomed Opt       Date:  2005 May-Jun       Impact factor: 3.170

5.  Genetic algorithm optimization for pre-processing and variable selection of spectroscopic data.

Authors:  Roger M Jarvis; Royston Goodacre
Journal:  Bioinformatics       Date:  2004-10-28       Impact factor: 6.937

6.  Kerr-gated time-resolved Raman spectroscopy of equine cortical bone tissue.

Authors:  Michael D Morris; Pavel Matousek; Michael Towrie; Anthony W Parker; Allen E Goodship; Edward R C Draper
Journal:  J Biomed Opt       Date:  2005 Jan-Feb       Impact factor: 3.170

7.  Raman spectroscopic evidence for octacalcium phosphate and other transient mineral species deposited during intramembranous mineralization.

Authors:  Nicole J Crane; Victoria Popescu; Michael D Morris; Pieter Steenhuis; Michael A Ignelzi
Journal:  Bone       Date:  2006-04-19       Impact factor: 4.398

8.  Identifying chemical changes in subchondral bone taken from murine knee joints using Raman spectroscopy.

Authors:  Karen A Dehring; Nicole J Crane; Abigail R Smukler; Jonathan B McHugh; Blake J Roessler; Michael D Morris
Journal:  Appl Spectrosc       Date:  2006-10       Impact factor: 2.388

9.  Subsurface probing in diffusely scattering media using spatially offset Raman spectroscopy.

Authors:  P Matousek; I P Clark; E R C Draper; M D Morris; A E Goodship; N Everall; M Towrie; W F Finney; A W Parker
Journal:  Appl Spectrosc       Date:  2005-04       Impact factor: 2.388

10.  Mineralization of developing mouse calvaria as revealed by Raman microspectroscopy.

Authors:  Catherine P Tarnowski; Michael A Ignelzi; Michael D Morris
Journal:  J Bone Miner Res       Date:  2002-06       Impact factor: 6.741

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  1 in total

1.  Machine Learning-Assisted Sampling of Surfance-Enhanced Raman Scattering (SERS) Substrates Improve Data Collection Efficiency.

Authors:  Tatu Rojalin; Dexter Antonio; Ambarish Kulkarni; Randy P Carney
Journal:  Appl Spectrosc       Date:  2021-08-03       Impact factor: 2.388

  1 in total

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