Literature DB >> 32943311

Biased Opioid Receptor Ligands: Gain without Pain.

Tyler C Beck1, Thomas A Dix2, Russell A Norris3.   

Abstract

Entities:  

Keywords:  agonist; biased; kappa opioids; pain

Mesh：

Substances：

Year:  2020        PMID： 32943311      PMCID： PMC7780734          DOI： 10.1016/j.tem.2020.08.005

Source DB:  PubMed          Journal:  Trends Endocrinol Metab        ISSN： 1043-2760            Impact factor:   12.015


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  10 in total

Review 1.  From nociception to pain perception: imaging the spinal and supraspinal pathways.

Authors:  Jonathan Brooks; Irene Tracey
Journal:  J Anat       Date:  2005-07       Impact factor: 2.610

Review 2.  Will peripherally restricted kappa-opioid receptor agonists (pKORAs) relieve pain with less opioid adverse effects and abuse potential?

Authors:  A Albert-Vartanian; M R Boyd; A L Hall; S J Morgado; E Nguyen; V P H Nguyen; S P Patel; L J Russo; A J Shao; R B Raffa
Journal:  J Clin Pharm Ther       Date:  2016-06-01       Impact factor: 2.512

3.  Biased agonists of the kappa opioid receptor suppress pain and itch without causing sedation or dysphoria.

Authors:  Tarsis F Brust; Jenny Morgenweck; Susy A Kim; Jamie H Rose; Jason L Locke; Cullen L Schmid; Lei Zhou; Edward L Stahl; Michael D Cameron; Sarah M Scarry; Jeffrey Aubé; Sara R Jones; Thomas J Martin; Laura M Bohn
Journal:  Sci Signal       Date:  2016-11-29       Impact factor: 8.192

Review 4.  Biased signalling: from simple switches to allosteric microprocessors.

Authors:  Jeffrey S Smith; Robert J Lefkowitz; Sudarshan Rajagopal
Journal:  Nat Rev Drug Discov       Date:  2018-01-05       Impact factor: 84.694

5.  Seeking (and Finding) Biased Ligands of the Kappa Opioid Receptor.

Authors:  Laura M Bohn; Jeffrey Aubé
Journal:  ACS Med Chem Lett       Date:  2017-07-05       Impact factor: 4.345

Review 6.  Biased Opioid Receptor Ligands: Gain without Pain.

Authors:  Ravi Ranjan; Shubhi Pandey; Arun K Shukla
Journal:  Trends Endocrinol Metab       Date:  2017-01-16       Impact factor: 12.015

7.  G protein signaling-biased agonism at the κ-opioid receptor is maintained in striatal neurons.

Authors:  Jo-Hao Ho; Edward L Stahl; Cullen L Schmid; Sarah M Scarry; Jeffrey Aubé; Laura M Bohn
Journal:  Sci Signal       Date:  2018-08-07       Impact factor: 8.192

Review 8.  When pain gets stuck: the evolution of pain chronification and treatment resistance.

Authors:  David Borsook; Andrew M Youssef; Laura Simons; Igor Elman; Christopher Eccleston
Journal:  Pain       Date:  2018-12       Impact factor: 7.926

9.  A BOILED-Egg To Predict Gastrointestinal Absorption and Brain Penetration of Small Molecules.

Authors:  Antoine Daina; Vincent Zoete
Journal:  ChemMedChem       Date:  2016-05-24       Impact factor: 3.466

Review 10.  A Review of the Therapeutic Potential of Recently Developed G Protein-Biased Kappa Agonists.

Authors:  Kendall L Mores; Benjamin R Cummins; Robert J Cassell; Richard M van Rijn
Journal:  Front Pharmacol       Date:  2019-04-17       Impact factor: 5.810
  10 in total

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