Harjinder Kaur1, Hosamadin Assadi2, Samer Alabed1,2, Donnie Cameron3, Vassilios S Vassiliou3, Jos J M Westenberg4, Rob van der Geest4, Liang Zhong5, Amardeep Dastidar6, Andrew J Swift1,2, Pankaj Garg1,2. 1. Sheffield Teaching Hospital NHS Foundation Trust, Sheffield S10 2JF, UK. 2. Department of Infection, Immunity & Cardiovascular Disease, University of Sheffield, Sheffield S10 2JF, UK. 3. Norwich Medical School, University of East Anglia, Norwich NR4 7TJ, UK. 4. Radiology, Leiden University Medical Centre, 2333 ZA Leiden, The Netherlands. 5. National Heart Centre Singapore, Duke-NUS Medical School, National University of Singapore, Singapore 169609, Singapore. 6. Bristol Heart Institute, Bristol BS2 8ED, UK.
Abstract
Background: There is an emerging body of evidence that supports the potential clinical value of left ventricular (LV) intracavity blood flow kinetic energy (KE) assessment using four-dimensional flow cardiovascular magnetic resonance imaging (4D flow CMR). The aim of this systematic review is to summarize studies evaluating LV intracavity blood flow KE quantification methods and its potential clinical significance. Methods: A systematic review search was carried out on Medline, Pubmed, EMBASE and CINAHL. Results: Of the 677 articles screened, 16 studies met eligibility. These included six (37%) studies on LV diastolic function, another six (37%) studies on heart failure or cardiomyopathies, three (19%) studies on ischemic heart disease or myocardial infarction and finally, one (6%) study on valvular heart disease, namely, mitral regurgitation. One of the main strengths identified by these studies is high reproducibility of LV blood flow KE hemodynamic assessment (mean coefficient of variability = 6 ± 2%) for the evaluation of LV diastolic function. Conclusions: The evidence gathered in this systematic review suggests that LV blood flow KE has great promise for LV hemodynamic assessment. Studies showed increased diagnostic confidence at no cost of additional time. Results were highly reproducible with low intraobserver variability.
Background: There is an emerging body of evidence that supports the potential clinical value of left ventricular (LV) intracavity blood flow kinetic energy (KE) assessment using four-dimensional flow cardiovascular magnetic resonance imaging (4D flow CMR). The aim of this systematic review is to summarize studies evaluating LV intracavity blood flow KE quantification methods and its potential clinical significance. Methods: A systematic review search was carried out on Medline, Pubmed, EMBASE and CINAHL. Results: Of the 677 articles screened, 16 studies met eligibility. These included six (37%) studies on LV diastolic function, another six (37%) studies on heart failure or cardiomyopathies, three (19%) studies on ischemic heart disease or myocardial infarction and finally, one (6%) study on valvular heart disease, namely, mitral regurgitation. One of the main strengths identified by these studies is high reproducibility of LV blood flow KE hemodynamic assessment (mean coefficient of variability = 6 ± 2%) for the evaluation of LV diastolic function. Conclusions: The evidence gathered in this systematic review suggests that LV blood flow KE has great promise for LV hemodynamic assessment. Studies showed increased diagnostic confidence at no cost of additional time. Results were highly reproducible with low intraobserver variability.
Authors: K Steding-Ehrenborg; P M Arvidsson; J Töger; M Rydberg; E Heiberg; M Carlsson; H Arheden Journal: Am J Physiol Heart Circ Physiol Date: 2015-10-23 Impact factor: 4.733
Authors: Majd AlGhatrif; James B Strait; Chris H Morrell; Marco Canepa; Jeanette Wright; Palchamy Elango; Angelo Scuteri; Samer S Najjar; Luigi Ferrucci; Edward G Lakatta Journal: Hypertension Date: 2013-09-03 Impact factor: 10.190
Authors: Petter Dyverfeldt; Malenka Bissell; Alex J Barker; Ann F Bolger; Carl-Johan Carlhäll; Tino Ebbers; Christopher J Francios; Alex Frydrychowicz; Julia Geiger; Daniel Giese; Michael D Hope; Philip J Kilner; Sebastian Kozerke; Saul Myerson; Stefan Neubauer; Oliver Wieben; Michael Markl Journal: J Cardiovasc Magn Reson Date: 2015-08-10 Impact factor: 5.364
Authors: Saul Crandon; Jos J M Westenberg; Peter P Swoboda; Graham J Fent; James R J Foley; Pei G Chew; Louise A E Brown; Christopher Saunderson; Abdallah Al-Mohammad; John P Greenwood; Rob J van der Geest; Erica Dall'Armellina; Sven Plein; Pankaj Garg Journal: Sci Rep Date: 2018-09-26 Impact factor: 4.379
Authors: Pankaj Garg; Rebecca Gosling; Peter Swoboda; Rachel Jones; Alexander Rothman; Jim M Wild; David G Kiely; Robin Condliffe; Samer Alabed; Andrew J Swift Journal: Eur Heart J Date: 2022-07-07 Impact factor: 35.855
Authors: Miroslawa Gorecka; Malenka M Bissell; David M Higgins; Pankaj Garg; Sven Plein; John P Greenwood Journal: J Cardiovasc Magn Reson Date: 2022-08-22 Impact factor: 6.903