| Literature DB >> 32913002 |
Trevor Bedford1,2,3, Alexander L Greninger4,5, Pavitra Roychoudhury4,5, Lea M Starita2,3, Michael Famulare6, Helen Y Chu2,7, Jay Shendure2,3,8, Keith R Jerome4,5, Meei-Li Huang4,5, Arun Nalla5, Gregory Pepper5, Adam Reinhardt5, Hong Xie5, Lasata Shrestha5, Truong N Nguyen5, Amanda Adler9, Elisabeth Brandstetter7, Shari Cho2,3, Danielle Giroux3, Peter D Han2,3, Kairsten Fay4, Chris D Frazar3, Misja Ilcisin4, Kirsten Lacombe9, Jover Lee4, Anahita Kiavand2,3, Matthew Richardson3, Thomas R Sibley4, Melissa Truong2,3, Caitlin R Wolf7, Deborah A Nickerson2,3, Mark J Rieder2,3, Janet A Englund2,9,10, James Hadfield4, Emma B Hodcroft11,12, John Huddleston4,13, Louise H Moncla4, Nicola F Müller4, Richard A Neher11,12, Xianding Deng14, Wei Gu14, Scot Federman14, Charles Chiu14, Jeffrey S Duchin7,15, Romesh Gautom16, Geoff Melly16, Brian Hiatt16, Philip Dykema16, Scott Lindquist16, Krista Queen17, Ying Tao17, Anna Uehara17, Suxiang Tong17, Duncan MacCannell18, Gregory L Armstrong18, Geoffrey S Baird5.
Abstract
After its emergence in Wuhan, China, in late November or early December 2019, the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus rapidly spread globally. Genome sequencing of SARS-CoV-2 allows the reconstruction of its transmission history, although this is contingent on sampling. We analyzed 453 SARS-CoV-2 genomes collected between 20 February and 15 March 2020 from infected patients in Washington state in the United States. We find that most SARS-CoV-2 infections sampled during this time derive from a single introduction in late January or early February 2020, which subsequently spread locally before active community surveillance was implemented.Entities:
Mesh：
Year: 2020 PMID： 32913002 DOI： 10.1126/science.abc0523
Source DB: PubMed Journal: Science ISSN： 0036-8075 Impact factor: 47.728