Literature DB >> 32888425

Are Organoids Ready for Prime Time?

Aparna Bhaduri1, Madeline G Andrews1, Arnold R Kriegstein2, Tomasz J Nowakowski3.   

Abstract

Innovations in organoid-based models of human tissues have made them an exciting experimental platform for studying development and disease. However, these models require systematic benchmarking against primary tissue to establish their value. We discuss key parameters that impact the utility of organoid models, primarily focusing on cerebral organoids as examples.
Copyright © 2020 Elsevier Inc. All rights reserved.

Entities:  

Mesh：

Year:  2020        PMID： 32888425      PMCID： PMC7559415          DOI： 10.1016/j.stem.2020.08.013

Source DB:  PubMed          Journal:  Cell Stem Cell        ISSN： 1875-9777            Impact factor:   24.633


  10 in total

1.  Self-organization of axial polarity, inside-out layer pattern, and species-specific progenitor dynamics in human ES cell-derived neocortex.

Authors:  Taisuke Kadoshima; Hideya Sakaguchi; Tokushige Nakano; Mika Soen; Satoshi Ando; Mototsugu Eiraku; Yoshiki Sasai
Journal:  Proc Natl Acad Sci U S A       Date:  2013-11-25       Impact factor: 11.205

Review 2.  Advances in Zika Virus Research: Stem Cell Models, Challenges, and Opportunities.

Authors:  Guo-Li Ming; Hengli Tang; Hongjun Song
Journal:  Cell Stem Cell       Date:  2016-12-01       Impact factor: 24.633

3.  Comparative Analysis and Refinement of Human PSC-Derived Kidney Organoid Differentiation with Single-Cell Transcriptomics.

Authors:  Haojia Wu; Kohei Uchimura; Erinn L Donnelly; Yuhei Kirita; Samantha A Morris; Benjamin D Humphreys
Journal:  Cell Stem Cell       Date:  2018-11-15       Impact factor: 24.633

4.  ERRγ Is Required for the Metabolic Maturation of Therapeutically Functional Glucose-Responsive β Cells.

Authors:  Eiji Yoshihara; Zong Wei; Chun Shi Lin; Sungsoon Fang; Maryam Ahmadian; Yasuyuki Kida; Tiffany Tseng; Yang Dai; Ruth T Yu; Christopher Liddle; Annette R Atkins; Michael Downes; Ronald M Evans
Journal:  Cell Metab       Date:  2016-04-12       Impact factor: 27.287

5.  Cerebral organoids model human brain development and microcephaly.

Authors:  Madeline A Lancaster; Magdalena Renner; Carol-Anne Martin; Daniel Wenzel; Louise S Bicknell; Matthew E Hurles; Tessa Homfray; Josef M Penninger; Andrew P Jackson; Juergen A Knoblich
Journal:  Nature       Date:  2013-08-28       Impact factor: 49.962

6.  Molecular Diversity of Midbrain Development in Mouse, Human, and Stem Cells.

Authors:  Gioele La Manno; Daniel Gyllborg; Simone Codeluppi; Kaneyasu Nishimura; Carmen Salto; Amit Zeisel; Lars E Borm; Simon R W Stott; Enrique M Toledo; J Carlos Villaescusa; Peter Lönnerberg; Jesper Ryge; Roger A Barker; Ernest Arenas; Sten Linnarsson
Journal:  Cell       Date:  2016-10-06       Impact factor: 41.582

7.  A robust ex vivo experimental platform for molecular-genetic dissection of adult human neocortical cell types and circuits.

Authors:  Jonathan T Ting; Brian Kalmbach; Peter Chong; Rebecca de Frates; C Dirk Keene; Ryder P Gwinn; Charles Cobbs; Andrew L Ko; Jeffrey G Ojemann; Richard G Ellenbogen; Christof Koch; Ed Lein
Journal:  Sci Rep       Date:  2018-05-30       Impact factor: 4.996

8.  Cerebral organoids at the air-liquid interface generate diverse nerve tracts with functional output.

Authors:  Stefano L Giandomenico; Susanna B Mierau; George M Gibbons; Lea M D Wenger; Laura Masullo; Timothy Sit; Magdalena Sutcliffe; Jerome Boulanger; Marco Tripodi; Emmanuel Derivery; Ole Paulsen; András Lakatos; Madeline A Lancaster
Journal:  Nat Neurosci       Date:  2019-03-18       Impact factor: 24.884

9.  Individual brain organoids reproducibly form cell diversity of the human cerebral cortex.

Authors:  Silvia Velasco; Amanda J Kedaigle; Sean K Simmons; Allison Nash; Marina Rocha; Giorgia Quadrato; Bruna Paulsen; Lan Nguyen; Xian Adiconis; Aviv Regev; Joshua Z Levin; Paola Arlotta
Journal:  Nature       Date:  2019-06-05       Impact factor: 49.962

10.  Cell stress in cortical organoids impairs molecular subtype specification.

Authors:  Aparna Bhaduri; Madeline G Andrews; Walter Mancia Leon; Diane Jung; David Shin; Denise Allen; Dana Jung; Galina Schmunk; Maximilian Haeussler; Jahan Salma; Alex A Pollen; Tomasz J Nowakowski; Arnold R Kriegstein
Journal:  Nature       Date:  2020-01-29       Impact factor: 69.504
  10 in total
  9 in total

1.  Evolving features of human cortical development and the emerging roles of non-coding RNAs in neural progenitor cell diversity and function.

Authors:  Kanella Prodromidou; Rebecca Matsas
Journal:  Cell Mol Life Sci       Date:  2021-12-18       Impact factor: 9.261

2.  [Establishment of a culture system for human nasal mucosa organoids with controllable differentiation].

Authors:  K Wang; Y Yu; R Han; X Wang; Y Zhao; H Tang; G Li
Journal:  Nan Fang Yi Ke Da Xue Xue Bao       Date:  2022-06-20

Review 3.  Patterning of brain organoids derived from human pluripotent stem cells.

Authors:  Zhijian Zhang; Richard O'Laughlin; Hongjun Song; Guo-Li Ming
Journal:  Curr Opin Neurobiol       Date:  2022-04-08       Impact factor: 7.070

Review 4.  Convergence of human pluripotent stem cell, organoid, and genome editing technologies.

Authors:  Lin Wang; Zhaohui Ye; Yoon-Young Jang
Journal:  Exp Biol Med (Maywood)       Date:  2021-01-19

5.  Assessing Gq-GPCR-induced human astrocyte reactivity using bioengineered neural organoids.

Authors:  Caroline Cvetkovic; Rajan Patel; Arya Shetty; Matthew K Hogan; Morgan Anderson; Nupur Basu; Samira Aghlara-Fotovat; Srivathsan Ramesh; Debosmita Sardar; Omid Veiseh; Michael E Ward; Benjamin Deneen; Philip J Horner; Robert Krencik
Journal:  J Cell Biol       Date:  2022-02-09       Impact factor: 8.077

Review 6.  Cerebral Organoids as an Experimental Platform for Human Neurogenomics.

Authors:  Tomasz J Nowakowski; Sofie R Salama
Journal:  Cells       Date:  2022-09-08       Impact factor: 7.666

7.  TGFβ superfamily signaling regulates the state of human stem cell pluripotency and capacity to create well-structured telencephalic organoids.

Authors:  Momoko Watanabe; Jessie E Buth; Jillian R Haney; Neda Vishlaghi; Felix Turcios; Lubayna S Elahi; Wen Gu; Caroline A Pearson; Arinnae Kurdian; Natella V Baliaouri; Amanda J Collier; Osvaldo A Miranda; Natassia Dunn; Di Chen; Shan Sabri; Luis de la Torre-Ubieta; Amander T Clark; Kathrin Plath; Heather R Christofk; Harley I Kornblum; Michael J Gandal; Bennett G Novitch
Journal:  Stem Cell Reports       Date:  2022-09-29       Impact factor: 7.294

Review 8.  Xenopus leads the way: Frogs as a pioneering model to understand the human brain.

Authors:  Cameron R T Exner; Helen Rankin Willsey
Journal:  Genesis       Date:  2020-12-27       Impact factor: 2.487

Review 9.  Emerging hiPSC Models for Drug Discovery in Neurodegenerative Diseases.

Authors:  Dorit Trudler; Swagata Ghatak; Stuart A Lipton
Journal:  Int J Mol Sci       Date:  2021-07-30       Impact factor: 5.923
  9 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.