Literature DB >> 32862445

Functioning, participation, and quality of life in children with intellectual disability: an observational study.

Katrina Williams1,2,3,4, Peter Jacoby5, Andrew Whitehouse5, Rachel Kim6, Amy Epstein5, Nada Murphy5, Sue Reid3,4, Helen Leonard5, Dinah Reddihough3,4,7, Jenny Downs5,8.   

Abstract

AIMS: To investigate associations between functioning, community participation, and quality of life (QoL) and identify whether participation mediates the effects of functioning on QoL.
METHOD: The caregivers of 435 children (211 females, 224 males; mean age 12y; SD 3y 11mo; age range 5-18y) with intellectual disability and autism spectrum disorder, cerebral palsy, Down syndrome, or Rett syndrome reported on their child's functioning (dependence for managing personal needs, mobility, communication, eye contact when speaking), frequency of participation, and QoL. Linear regression and mediation analyses were used to evaluate the relationships between child functioning, participation, and QoL.
RESULTS: Children with greater dependency for managing personal needs and limited eye contact when speaking experienced poorer QoL. Less impaired functioning was associated with more frequent participation, which, in turn, was associated with a 3-point gain in QoL for each additional point in frequency of participation (coefficient=2.67, 95% confidence interval 1.56-3.78). The effect of impaired functioning on QoL was partially mediated by participation in children with greater dependency in managing personal needs and those with mildly impaired communication.
INTERPRETATION: Greater levels of impairments with poorer functioning, notably a high level of dependence, were associated with poorer QoL. Poorer QoL can be partly explained by less frequent community participation.
© 2020 Mac Keith Press.

Entities:  

Year:  2020        PMID: 32862445     DOI: 10.1111/dmcn.14657

Source DB:  PubMed          Journal:  Dev Med Child Neurol        ISSN: 0012-1622            Impact factor:   5.449


  4 in total

1.  The effect of functioning on Quality of Life Inventory-Disability measured quality of life is not mediated or moderated by parental psychological distress.

Authors:  A J O Whitehouse; P Jacoby; D Reddihough; H Leonard; K Williams; Jenny Downs
Journal:  Qual Life Res       Date:  2021-05-03       Impact factor: 4.147

2.  Devising a Missing Data Rule for a Quality of Life Questionnaire-A Simulation Study.

Authors:  Peter Jacoby; Andrew Whitehouse; Helen Leonard; Jacinta Saldaris; Scott Demarest; Tim Benke; Jenny Downs
Journal:  J Dev Behav Pediatr       Date:  2022-01-24       Impact factor: 2.988

Review 3.  Movement disorders in patients with Rett syndrome: A systematic review of evidence and associated clinical considerations.

Authors:  Jatinder Singh; Evamaria Lanzarini; Nardo Nardocci; Paramala Santosh
Journal:  Psychiatry Clin Neurosci       Date:  2021-10-21       Impact factor: 12.145

4.  Modelling quality of life in children with intellectual disability using regression trees.

Authors:  Peter Jacoby; Katrina Williams; Dinah Reddihough; Helen Leonard; Andrew Whitehouse; Jenny Downs
Journal:  Dev Med Child Neurol       Date:  2022-03-23       Impact factor: 4.864

  4 in total

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