Literature DB >> 32797261

Population-based analysis of cost and peri-operative outcomes between open and robotic primary retroperitoneal lymph node dissection for germ cell tumors.

Raj Bhanvadia1, Caleb Ashbrook2, Aditya Bagrodia2, Yair Lotan2, Vitaly Margulis2, Solomon Woldu2.   

Abstract

PURPOSE: To compare perioperative outcomes and perform the first cost analysis between open retroperitoneal lymph node dissection (O-RPLND) and Robotic-RPLND (R-RPLND) using a national all-payer inpatient care database.
METHODS: Nationwide Inpatient Sample (NIS) was queried between 2013-2016 for primary RPLND and germ cell tumor. We compared cost, length of stay (LOS), and complications between O-RPLND and R-RPLND. Linear regression plots identified point of cost equivalence between R-RPLND and O-RPLND. A multivariable linear regression model was generated to analyze predictors of cost.
RESULTS: 44 cases of R-RPLND and 319 cases of O-RPLND were identified. R-RPLND was associated with lower rate of complications (0% vs. 16.6%, p < 0.01) and shorter LOS [Median (IQR): 1.5 (1-3) days vs. 4 (3-6) days, p < 0.01]. Rates of ileus, genitourinary complications, and transfusions were lower with R-RPLND, but did not reach significance. On multivariable analysis, robotic approach independently contributed $4457, while each day of hospitalization contributed to an additional $2,431 to the overall model of cost. Linear regression plots determined point of cost equivalence between an R-RPLND staying a mean of 2 days was 4-5 days for O-RPLND, supporting the multivariable analysis. Total hospitalization cost was equivalent between R-RPLND and O-RPLND [Median (IQR): $15,681($12,735-$21,596) vs $16,718($11,799-$24,403), p = 0.48]-suggesting that the cost equivalency of R-RPLND is, at least in part, attributable to shorter LOS.
CONCLUSION: While O-RPLND remains the gold standard and this study is limited by selection bias of a robotic approach to RPLND, our findings suggest primary R-RPLND may represent a cost-equivalent option with decreased hospital LOS in select cases.

Entities:  

Keywords:  Health services research; Minimally invasive surgery; Peri-operative outcomes; Retroperitoneal lymphadenectomy; Testis cancer

Year:  2020        PMID: 32797261     DOI: 10.1007/s00345-020-03403-9

Source DB:  PubMed          Journal:  World J Urol        ISSN: 0724-4983            Impact factor:   4.226


  22 in total

Review 1.  Robot-assisted retroperitoneal lymph node dissection in testicular cancer.

Authors:  Haidar M Abdul-Muhsin; James O L'esperance; Kimberly Fischer; Michael E Woods; James R Porter; Erik P Castle
Journal:  J Surg Oncol       Date:  2015-09-09       Impact factor: 3.454

Review 2.  Andrological complications following retroperitoneal lymph node dissection for testicular cancer.

Authors:  Alessandro Crestani; Francesco Esperto; Marta Rossanese; Gianluca Giannarini; Nicola Nicolai; Vincenzo Ficarra
Journal:  Minerva Urol Nefrol       Date:  2016-11-23       Impact factor: 3.720

3.  Guidelines on Testicular Cancer: 2015 Update.

Authors:  Peter Albers; Walter Albrecht; Ferran Algaba; Carsten Bokemeyer; Gabriella Cohn-Cedermark; Karim Fizazi; Alan Horwich; Maria Pilar Laguna; Nicola Nicolai; Jan Oldenburg
Journal:  Eur Urol       Date:  2015-08-18       Impact factor: 20.096

4.  Complications of primary nerve sparing retroperitoneal lymph node dissection for clinical stage I nonseminomatous germ cell tumors of the testis: experience of the German Testicular Cancer Study Group.

Authors:  Axel Heidenreich; Peter Albers; Michael Hartmann; Sabine Kliesch; Kai-Uwe Kohrmann; Susanne Krege; Philipp Lossin; Lothar Weissbach
Journal:  J Urol       Date:  2003-05       Impact factor: 7.450

5.  Safety and Early Oncologic Effectiveness of Primary Robotic Retroperitoneal Lymph Node Dissection for Nonseminomatous Germ Cell Testicular Cancer.

Authors:  Shane M Pearce; Shay Golan; Michael A Gorin; Amy N Luckenbaugh; Stephen B Williams; John F Ward; Jeffrey S Montgomery; Khaled S Hafez; Alon Z Weizer; Phillip M Pierorazio; Mohamad E Allaf; Scott E Eggener
Journal:  Eur Urol       Date:  2016-05-24       Impact factor: 20.096

Review 6.  Robotic Primary RPLND for Stage I Testicular Cancer: a Review of Indications and Outcomes.

Authors:  Heather J Chalfin; Wesley Ludwig; Phillip M Pierorazio; Mohamad E Allaf
Journal:  Curr Urol Rep       Date:  2016-05       Impact factor: 3.092

Review 7.  Open retroperitoneal lymph node dissection.

Authors:  Jerome P Richie
Journal:  Can J Urol       Date:  2005-02       Impact factor: 1.344

8.  Nationwide Patterns of Care for Stage II Nonseminomatous Germ Cell Tumor of the Testicle.

Authors:  Rashed Ghandour; Caleb Ashbrook; Yuval Freifeld; Nirmish Singla; Jose M El-Asmar; Yair Lotan; Vitaly Margulis; Scott Eggener; Solomon Woldu; Aditya Bagrodia
Journal:  Eur Urol Oncol       Date:  2019-07-01

9.  Diagnosis and Treatment of Early Stage Testicular Cancer: AUA Guideline.

Authors:  Andrew Stephenson; Scott E Eggener; Eric B Bass; David M Chelnick; Siamak Daneshmand; Darren Feldman; Timothy Gilligan; Jose A Karam; Bradley Leibovich; Stanley L Liauw; Timothy A Masterson; Joshua J Meeks; Phillip M Pierorazio; Ritu Sharma; Joel Sheinfeld
Journal:  J Urol       Date:  2019-07-08       Impact factor: 7.450

10.  Complications of open primary and post-chemotherapy retroperitoneal lymph node dissection for testicular cancer.

Authors:  Vairavan S Subramanian; Carvell T Nguyen; Andrew J Stephenson; Eric A Klein
Journal:  Urol Oncol       Date:  2008-12-20       Impact factor: 3.498

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  1 in total

Review 1.  Robotic RPLND for stage IIA/B nonseminoma: the Princess Margaret Experience.

Authors:  G J Nason; Robert J Hamilton
Journal:  World J Urol       Date:  2022-01-06       Impact factor: 4.226

  1 in total

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