| Literature DB >> 32730240 |
Marissa B Esser, Adam Sherk, Yong Liu, Timothy S Naimi, Timothy Stockwell, Mandy Stahre, Dafna Kanny, Michael Landen, Richard Saitz, Robert D Brewer.
Abstract
Excessive alcohol use is a leading cause of preventable death in the United States (1) and costs associated with it, such as those from losses in workplace productivity, health care expenditures, and criminal justice, were $249 billion in 2010 (2). CDC used the Alcohol-Related Disease Impact (ARDI) application* to estimate national and state average annual alcohol-attributable deaths and years of potential life lost (YPLL) during 2011-2015, including deaths from one's own excessive drinking (e.g., liver disease) and from others' drinking (e.g., passengers killed in alcohol-related motor vehicle crashes). This study found an average of 93,296 alcohol-attributable deaths (255 deaths per day) and 2.7 million YPLL (29 years of life lost per death, on average) in the United States each year. Of all alcohol-attributable deaths, 51,078 (54.7%) were caused by chronic conditions, and 52,361 (56.0%) involved adults aged 35-64 years. Age-adjusted alcohol-attributable deaths per 100,000 population ranged from 20.3 in New Jersey and New York to 52.3 in New Mexico. YPLL per 100,000 population ranged from 613.8 in New York to 1,651.7 in New Mexico. Implementation of effective strategies for preventing excessive drinking, including those recommended by the Community Preventive Services Task Force (e.g., increasing alcohol taxes and regulating the number and concentration of alcohol outlets), could reduce alcohol-attributable deaths and YPLL.†.Entities:
Mesh:
Year: 2020 PMID: 32730240 PMCID: PMC7392395 DOI: 10.15585/mmwr.mm6930a1
Source DB: PubMed Journal: MMWR Morb Mortal Wkly Rep ISSN: 0149-2195 Impact factor: 17.586
Average annual number of deaths and years of potential life lost attributable to excessive alcohol use,* by condition and sex — United States, 2011–2015
| Cause | Alcohol-attributable deaths | Years of potential life lost | ||||
|---|---|---|---|---|---|---|
| Total† | Males no. (%) | Females no. (%) | Total† | Males no. (%) | Females no. (%) | |
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| 51,078 | 35,583 (69.7) | 15,495 (30.3) | 1,105,190 | 752,936 (68.1) | 352,253 (31.9) |
| Alcohol abuse | 2,591 | 1,986 (76.6) | 605 (23.4) | 66,839 | 49,129 (73.5) | 17,710 (26.5) |
| Alcohol cardiomyopathy | 510 | 432 (84.7) | 78 (15.3) | 12,235 | 10,136 (82.8) | 2,099 (17.2) |
| Alcohol dependence syndrome | 4,258 | 3,269 (76.8) | 989 (23.2) | 109,911 | 81,192 (73.9) | 28,719 (26.1) |
| Alcohol polyneuropathy | 3 | 3 (100.0) | 0 (—) | 54 | 54 (100.0) | 0 (—) |
| Alcoholic gastritis | 33 | 26 (78.8) | 7 (21.2) | 890 | 696 (78.2) | 194 (21.8) |
| Alcoholic liver disease | 18,164 | 12,887 (70.9) | 5,277 (29.1) | 467,996 | 313,897 (67.1) | 154,099 (32.9) |
| Alcoholic myopathy | 0 | 0 (—) | 0 (—) | 0 | 0 (—) | 0 (—) |
| Alcoholic psychosis | 703 | 549 (78.1) | 154 (21.9) | 14,129 | 10,799 (76.4) | 3,330 (23.6) |
| Alcohol-induced acute pancreatitis | 278 | 214 (77.0) | 64 (23.0) | 8,284 | 6,247 (75.4) | 2,037 (24.6) |
| Alcohol-induced chronic pancreatitis | 52 | 38 (73.1) | 14 (26.9) | 1,507 | 1,046 (69.4) | 461 (30.6) |
| Atrial fibrillation | 329 | 228 (69.3) | 100 (30.4) | 2,943 | 2,084 (70.8) | 860 (29.2) |
| Cancer, breast (females only) | 584 | NA | 584 (NA) | 11,203 | NA | 11,203 (NA) |
| Cancer, colorectal | 996 | 898 (90.2) | 98 (9.8) | 15,540 | 14,016 (90.2) | 1,524 (9.8) |
| Cancer, esophageal§ | 494 | 430 (87.0) | 64 (13.0) | 8,038 | 7,007 (87.2) | 1,031 (12.8) |
| Cancer, laryngeal | 248 | 233 (94.0) | 15 (6.0) | 4,002 | 3,737 (93.4) | 265 (6.6) |
| Cancer, liver | 1,609 | 1,545 (96.0) | 64 (4.0) | 28,191 | 27,129 (96.2) | 1,061 (3.8) |
| Cancer, oral cavity and pharyngeal | 909 | 830 (91.3) | 79 (8.7) | 16,034 | 14,715 (91.8) | 1,319 (8.2) |
| Cancer, pancreatic¶ | 186 | 151 (81.2) | 35 (18.8) | 2,827 | 2,301 (81.4) | 526 (18.6) |
| Cancer, prostate (males only) | 188 | 188 (NA) | NA | 1,952 | 1,952 (NA) | NA |
| Cancer, stomach¶ | 58 | 56 (96.6) | 3 (5.2) | 943 | 897 (95.1) | 46 (4.9) |
| Chronic hepatitis | 2 | 2 (100.0) | 0 (0.0) | 42 | 36 (85.7) | 6 (14.3) |
| Coronary heart disease | 3,537 | 2,971 (84.0) | 567 (16.0) | 46,698 | 40,183 (86.0) | 6,515 (14.0) |
| Degeneration of nervous system attributable to alcohol | 145 | 118 (81.4) | 27 (18.6) | 2,617 | 2,030 (77.6) | 587 (22.4) |
| Esophageal varices | 112 | 77 (68.8) | 34 (30.4) | 2,414 | 1,711 (70.9) | 703 (29.1) |
| Fetal alcohol syndrome | 4 | 2 (50.0) | 2 (50.0) | 212 | 122 (57.5) | 90 (42.5) |
| Fetus and newborn affected by maternal use of alcohol | 1 | 1 (100.0) | 0 (0.0) | 76 | 76 (100.0) | 0 (—) |
| Gallbladder disease | 0 | 0 (—) | 0 (—) | 0 | 0 (—) | 0 (—) |
| Gastroesophageal hemorrhage | 31 | 20 (64.5) | 10 (32.3) | 517 | 359 (69.4) | 157 (30.4) |
| Hypertension | 3,584 | 1,638 (45.7) | 1,946 (54.3) | 50,016 | 26,021 (52.0) | 23,994 (48.0) |
| Infant death, low birthweight** | 2 | 1 (50.0) | 1 (50.0) | 133 | 69 (51.9) | 65 (48.9) |
| Infant death, preterm birth** | 44 | 24 (54.5) | 19 (43.2) | 3,410 | 1,845 (54.1) | 1,565 (45.9) |
| Infant death, small for gestational age** | 0 | 0 (—) | 0 (—) | 13 | 5 (38.5) | 7 (53.8) |
| Liver cirrhosis, unspecified | 9,801 | 5,696 (58.1) | 4,105 (41.9) | 197,875 | 114,580 (57.9) | 83,295 (42.1) |
| Pancreatitis, acute | 0 | 0 (—) | 0 (—) | 0 | 0 (—) | 0 (—) |
| Pancreatitis, chronic | 15 | 12 (80.0) | 3 (20.0) | 317 | 252 (79.5) | 65 (20.5) |
| Pneumonia†† | 133 | 105 (78.9) | 29 (21.8) | 3,714 | 2,839 (76.4) | 875 (23.6) |
| Portal hypertension | 61 | 34 (55.7) | 26 (42.6) | 1,267 | 729 (57.5) | 538 (42.5) |
| Stroke, hemorrhagic | 938 | 565 (60.2) | 374 (39.9) | 14,497 | 8,856 (61.1) | 5,641 (38.9) |
| Stroke, ischemic | 342 | 243 (71.1) | 100 (29.2) | 3,867 | 2,837 (73.4) | 1,030 (26.6) |
| Unprovoked seizures, epilepsy, or seizure disorder | 134 | 112 (83.6) | 22 (16.4) | 3,987 | 3,352 (84.1 | 635 (15.9) |
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| 42,218 | 30,935 (73.3) | 11,283 (26.7) | 1,578,021 | 1,146,153 (72.6) | 431,868 (27.4) |
| Air-space transport | 75 | 64 (85.3) | 11 (14.7) | 2,268 | 1,867 (82.3) | 401 (17.7) |
| Alcohol poisoning | 2,288 | 1,735 (75.8) | 553 (24.2) | 76,224 | 56,511 (74.1) | 19,713 (25.9) |
| Aspiration | 255 | 141 (55.3) | 114 (44.7) | 4,765 | 2,695 (56.6) | 2,070 (43.4) |
| Child maltreatment§§ | 148 | 87 (58.8) | 61 (41.2) | 11,000 | 6,294 (57.2) | 4,706 (42.8) |
| Drowning | 981 | 772 (78.7) | 210 (21.4) | 33,853 | 27,108 (80.1) | 6,745 (19.9) |
| Fall injuries¶¶ | 2,645 | 1,873 (70.8) | 772 (29.2) | 70,815 | 49,887 (70.4) | 20,927 (29.6) |
| Fire injuries | 457 | 274 (60.0) | 183 (40.0) | 10,950 | 6,491 (59.3) | 4,459 (40.7) |
| Firearm injuries | 337 | 284 (84.3) | 53 (15.7) | 12,917 | 10,768 (83.4) | 2,149 (16.6) |
| Homicide | 5,306 | 4,267 (80.4) | 1,039 (19.6) | 230,047 | 187,052 (81.3) | 42,995 (18.7) |
| Hypothermia | 296 | 194 (65.5) | 102 (34.5) | 6,199 | 4,354 (70.2) | 1,845 (29.8) |
| Motor-vehicle nontraffic crashes | 190 | 144 (75.8) | 47 (24.7) | 5,588 | 4,249 (76.0) | 1,339 (24.0) |
| Motor-vehicle traffic crashes*** | 7,092 | 5,522 (77.9) | 1,570 (22.1) | 323,610 | 245,447 (75.8) | 78,163 (24.2) |
| Occupational and machine injuries | 126 | 117 (92.9) | 9 (7.1) | 3,294 | 3,060 (92.9) | 234 (7.1) |
| Other road vehicle crashes | 170 | 137 (80.6) | 33 (19.4) | 5,632 | 4,473 (79.4) | 1,159 (20.6) |
| Poisoning (not alcohol) | 11,839 | 7,524 (63.6) | 4,315 (36.4) | 444,235 | 280,270 (63.1) | 163,965 (36.9) |
| Suicide | 9,899 | 7,711 (77.9) | 2,189 (22.1) | 332,791 | 252,674 (75.9) | 80,117 (24.1) |
| Suicide by and exposure to alcohol | 38 | 24 (63.2) | 14 (36.8) | 1,267 | 764 (60.3) | 503 (39.7) |
| Water transport | 75 | 65 (86.7) | 9 (12.0) | 2,566 | 2,189 (85.3) | 377 (14.7) |
Abbreviation: NA = not applicable.
* In the Alcohol-Related Disease Impact application (https://www.cdc.gov/ARDI), deaths attributable to excessive alcohol use include deaths from 1) conditions that are 100% alcohol-attributable, 2) deaths caused by acute conditions that involved binge drinking, and 3) deaths caused by chronic conditions that involved medium (>1 to ≤2 drinks of alcohol [women] or >2 to ≤4 drinks [men]) or high (>2 drinks of alcohol [women] or >4 drinks [men]) levels of average daily alcohol consumption.
† Numbers might not sum to totals, and row percentages might not sum to 100% because of rounding.
§ Deaths calculated for the proportion of esophageal cancer deaths caused by squamous cell carcinoma only, based on the Surveillance, Epidemiology, and End Results data in 18 states (SEER18). https://seer.cancer.gov/.
¶ Deaths among those consuming high average daily levels of alcohol only.
** Alcohol consumption prevalence estimates calculated among women aged 18–44 years only.
†† Deaths among persons aged 20–64 years only because of the high number of deaths from pneumonia among persons aged ≥65 years that are not alcohol-related and the lack of relative risks that differ by age.
§§ Deaths among persons aged 0–14 years.
¶¶ Deaths among persons aged 15–69 years only because of the high number of deaths from falls among persons aged ≥70 years that are not alcohol-attributable and the lack of alcohol-attributable fractions that differ by age.
*** Deaths among persons of all ages. A blood alcohol concentration level of ≥0.08 g/dL is used for defining alcohol attribution for this condition.
Annual average number of deaths and years of potential life lost from excessive alcohol use,* by state — United States, 2011–2015
| Location | Alcohol-attributable deaths | Age-adjusted alcohol-attributable deaths per 100,000-population | Years of potential life lost | Years of potential life lost per 100,000-population | Years of potential life lost per alcohol-attributable death |
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| Alabama | 1,446 | 28.0 | 44,074 | 912.4 | 30.5 |
| Alaska | 292 | 29.4† | 9,631 | 1,313.2 | 33.0 |
| Arizona | 2,594 | 37.0 | 74,450 | 1,120.9 | 28.7 |
| Arkansas | 892 | 28.3 | 26,512 | 896.2 | 29.7 |
| California | 10,811 | 26.9 | 299,336 | 779.1 | 27.7 |
| Colorado | 1,810 | 32.5 | 54,054 | 1,024.0 | 29.9 |
| Connecticut | 900 | 22.8 | 25,738 | 716.3 | 28.6 |
| Delaware | 271 | 19.3† | 8,136 | 878.2 | 30.0 |
| District of Columbia | 207 | 26.4† | 5,861 | 905.2 | 28.3 |
| Florida | 6,778 | 29.8 | 183,199 | 932.5 | 27.0 |
| Georgia | 2,556 | 24.7 | 75,681 | 756.3 | 29.6 |
| Hawaii | 348 | 17.1† | 9,470 | 673.4 | 27.2 |
| Idaho | 491 | 29.5 | 14,037 | 868.3 | 28.6 |
| Illinois | 3,295 | 24.0 | 95,560 | 742.3 | 29.0 |
| Indiana | 1,900 | 27.4 | 56,502 | 860.2 | 29.7 |
| Iowa | 834 | 24.5 | 22,014 | 711.6 | 26.4 |
| Kansas | 750 | 24.7 | 22,152 | 765.7 | 29.5 |
| Kentucky | 1,524 | 32.3 | 45,422 | 1,032.9 | 29.8 |
| Louisiana | 1,523 | 31.5 | 47,217 | 1,020.9 | 31.0 |
| Maine | 424 | 18.8† | 11,261 | 847.3 | 26.6 |
| Maryland | 1,453 | 22.9 | 43,804 | 738.6 | 30.1 |
| Massachusetts | 1,729 | 23.3 | 48,305 | 720.4 | 27.9 |
| Michigan | 3,123 | 28.9 | 89,332 | 902.3 | 28.6 |
| Minnesota | 1,333 | 22.7 | 36,537 | 674.2 | 27.4 |
| Mississippi | 913 | 29.3 | 27,950 | 935.4 | 30.6 |
| Missouri | 1,860 | 28.8 | 55,813 | 923.2 | 30.0 |
| Montana | 414 | 37.4 | 12,232 | 1,205.5 | 29.5 |
| Nebraska | 453 | 23.0 | 12,610 | 674.6 | 27.8 |
| Nevada | 1,037 | 34.6 | 29,604 | 1,057.8 | 28.5 |
| New Hampshire | 420 | 20.1† | 11,364 | 858.2 | 27.1 |
| New Jersey | 1,967 | 20.3 | 57,455 | 645.2 | 29.2 |
| New Mexico | 1,129 | 52.3 | 34,424 | 1,651.7 | 30.5 |
| New York | 4,390 | 20.3 | 120,761 | 613.8 | 27.5 |
| North Carolina | 2,811 | 26.5 | 82,568 | 838.7 | 29.4 |
| North Dakota | 215 | 21.2† | 6,352 | 880.2 | 29.5 |
| Ohio | 3,608 | 28.6 | 103,809 | 896.8 | 28.8 |
| Oklahoma | 1,465 | 36.4 | 43,597 | 1,132.5 | 29.8 |
| Oregon | 1,498 | 33.5 | 39,310 | 997.9 | 26.2 |
| Pennsylvania | 3,768 | 26.5 | 108,168 | 846.4 | 28.7 |
| Rhode Island | 337 | 20.5† | 9,240 | 876.9 | 27.4 |
| South Carolina | 1,629 | 31.4 | 48,121 | 1,007.2 | 29.5 |
| South Dakota | 282 | 22.0† | 8,608 | 1,020.9 | 30.5 |
| Tennessee | 2,102 | 30.0 | 62,325 | 958.9 | 29.7 |
| Texas | 7,097 | 26.9 | 213,553 | 804.7 | 30.1 |
| Utah | 68 | 26.1 | 21,803 | 751.0 | 31.9 |
| Vermont | 203 | 21.0† | 5,074 | 809.8 | 25.0 |
| Virginia | 1,972 | 22.2 | 56,965 | 689.9 | 28.9 |
| Washington | 2,195 | 28.8 | 59,665 | 854.1 | 27.2 |
| West Virginia | 725 | 35.3 | 21,621 | 1,167.8 | 29.8 |
| Wisconsin | 1,722 | 27.2 | 47,374 | 825.0 | 27.5 |
| Wyoming | 236 | 27.1† | 7,317 | 1,262.3 | 31.0 |
* In the Alcohol-Related Disease Impact application (https://www.cdc.gov/ARDI), deaths attributable to excessive alcohol use include deaths from 1) conditions that are 100% alcohol-attributable, 2) deaths caused by acute conditions that involved binge drinking, and 3) deaths caused by chronic conditions that involved medium (>1 to ≤2 drinks of alcohol [women] or >2 to ≤4 drinks [men]) or high (>2 drinks of alcohol [women] or >4 drinks [men]) levels of average daily alcohol consumption.
† The estimate might be unreliable because of suppressed estimates of the number of alcohol-attributable deaths in two or more age groups, and estimates might not account for the total number of alcohol-attributable deaths in the state.
FIGUREAverage annual number of deaths attributable to excessive alcohol use,* by sex and age group — United States, 2011–2015
* In the Alcohol-Related Disease Impact application (https://www.cdc.gov/ARDI), deaths attributable to excessive alcohol use include deaths from 1) conditions that are 100% alcohol-attributable, 2) deaths caused by acute conditions that involved binge drinking, and 3) deaths caused by chronic conditions that involved medium (>1 to ≤2 drinks of alcohol [women] or >2 to ≤4 drinks [men]) or high (>2 drinks of alcohol [women] or >4 drinks [men]) levels of average daily alcohol consumption.