Literature DB >> 32723087

Metabolic Profiling of Blood and Urine for Exploring the Functional Role of the Microbiota in Human Health.

Ana F Diallo1, Mark B Lockwood2, Katherine A Maki2, Alexis T Franks3, Abhrarup Roy3, Rosario Jaime-Lara3, Paule V Joseph3, Wendy A Henderson4, Seon Yoon Chung5, Jacqueline McGrath6, Stefan J Green7, Anne M Fink2.   

Abstract

The quantification of metabolites in blood and urine allows nurses to explore new hypotheses about the microbiome. This review summarizes findings from recent studies with a focus on how the state of the science can influence future nursing research initiatives. Metabolomics can advance nursing research by identifying physiologic/pathophysiologic processes underlying patients' symptoms and can be useful for testing the effects of nursing interventions. To date, metabolomics has been used to study cardiovascular, respiratory, endocrine, autoimmune, and infectious conditions, with research focused on understanding the microbial metabolism of substrates resulting in circulating/excreted biomarkers such as trimethylamine N-oxide. This review provides specific recommendations for the collection of specimens and goals for future studies.

Entities:  

Keywords:  blood; cardiovascular; diabetes; metabolomics; microbiome; nursing; trimethylamine n-oxide; urine

Year:  2020        PMID： 32723087      PMCID： PMC7874358          DOI： 10.1177/1099800420941080

Source DB:  PubMed          Journal:  Biol Res Nurs        ISSN： 1099-8004            Impact factor:   2.522


  36 in total

1.  The microbial metabolite trimethylamine-N-oxide in association with inflammation and microbial dysregulation in three HIV cohorts at various disease stages.

Authors:  Catharina Missailidis; Ujjwal Neogi; Peter Stenvinkel; Marius Trøseid; Piotr Nowak; Peter Bergman
Journal:  AIDS       Date:  2018-07-31       Impact factor: 4.177

2.  Considerations When Designing a Microbiome Study: Implications for Nursing Science.

Authors:  Katherine A Maki; Ana F Diallo; Mark B Lockwood; Alexis T Franks; Stefan J Green; Paule V Joseph
Journal:  Biol Res Nurs       Date:  2018-11-08       Impact factor: 2.522

3.  Gut microbiome and serum metabolome alterations in obesity and after weight-loss intervention.

Authors:  Ruixin Liu; Jie Hong; Xiaoqiang Xu; Qiang Feng; Dongya Zhang; Yanyun Gu; Juan Shi; Shaoqian Zhao; Wen Liu; Xiaokai Wang; Huihua Xia; Zhipeng Liu; Bin Cui; Peiwen Liang; Liuqing Xi; Jiabin Jin; Xiayang Ying; Xiaolin Wang; Xinjie Zhao; Wanyu Li; Huijue Jia; Zhou Lan; Fengyu Li; Rui Wang; Yingkai Sun; Minglan Yang; Yuxin Shen; Zhuye Jie; Junhua Li; Xiaomin Chen; Huanzi Zhong; Hailiang Xie; Yifei Zhang; Weiqiong Gu; Xiaxing Deng; Baiyong Shen; Xun Xu; Huanming Yang; Guowang Xu; Yufang Bi; Shenghan Lai; Jian Wang; Lu Qi; Lise Madsen; Jiqiu Wang; Guang Ning; Karsten Kristiansen; Weiqing Wang
Journal:  Nat Med       Date:  2017-06-19       Impact factor: 53.440

4.  Gut Microbial-Related Choline Metabolite Trimethylamine-N-Oxide Is Associated With Progression of Carotid Artery Atherosclerosis in HIV Infection.

Authors:  Zhilei Shan; Clary B Clish; Simin Hua; Justin M Scott; David B Hanna; Robert D Burk; Sabina A Haberlen; Sanjiv J Shah; Joseph B Margolick; Cynthia L Sears; Wendy S Post; Alan L Landay; Jason M Lazar; Howard N Hodis; Kathryn Anastos; Robert C Kaplan; Qibin Qi
Journal:  J Infect Dis       Date:  2018-09-22       Impact factor: 5.226

5.  Prognostic Value of Plasma Trimethylamine N-Oxide Levels in Patients with Acute Ischemic Stroke.

Authors:  Qijin Zhai; Xiang Wang; Chun Chen; Yan Tang; Yuqian Wang; Jisha Tian; Ying Zhao; Xinfeng Liu
Journal:  Cell Mol Neurobiol       Date:  2019-07-22       Impact factor: 5.046

6.  Dysbiosis of urinary microbiota is positively correlated with type 2 diabetes mellitus.

Authors:  Fengping Liu; Zongxin Ling; Yonghong Xiao; Longxian Lv; Qing Yang; Baohong Wang; Haifeng Lu; Li Zheng; Ping Jiang; Wei Wang; Lanjuan Li
Journal:  Oncotarget       Date:  2017-01-17

7.  Associations of serum indolepropionic acid, a gut microbiota metabolite, with type 2 diabetes and low-grade inflammation in high-risk individuals.

Authors:  Marjo Tuomainen; Jaana Lindström; Marko Lehtonen; Seppo Auriola; Jussi Pihlajamäki; Markku Peltonen; Jaakko Tuomilehto; Matti Uusitupa; Vanessa D de Mello; Kati Hanhineva
Journal:  Nutr Diabetes       Date:  2018-05-25       Impact factor: 5.097

8.  Elevated circulating levels of succinate in human obesity are linked to specific gut microbiota.

Authors:  Carolina Serena; Victoria Ceperuelo-Mallafré; Noelia Keiran; Maria Isabel Queipo-Ortuño; Rosa Bernal; Ricardo Gomez-Huelgas; Mireia Urpi-Sarda; Mónica Sabater; Vicente Pérez-Brocal; Cristina Andrés-Lacueva; Andres Moya; Francisco J Tinahones; Jose Manuel Fernández-Real; Joan Vendrell; Sonia Fernández-Veledo
Journal:  ISME J       Date:  2018-02-12       Impact factor: 10.302

9.  Dynamics of Human Gut Microbiota and Short-Chain Fatty Acids in Response to Dietary Interventions with Three Fermentable Fibers.

Authors:  Nielson T Baxter; Alexander W Schmidt; Arvind Venkataraman; Kwi S Kim; Clive Waldron; Thomas M Schmidt
Journal:  mBio       Date:  2019-01-29       Impact factor: 7.867

10.  Microbiota-derived Trimethylamine N-oxide Predicts Cardiovascular Risk After STEMI.

Authors:  Yasushi Matsuzawa; Hidefumi Nakahashi; Masaaki Konishi; Ryosuke Sato; Chika Kawashima; Shinnosuke Kikuchi; Eiichi Akiyama; Noriaki Iwahashi; Nobuhiko Maejima; Kozo Okada; Toshiaki Ebina; Kiyoshi Hibi; Masami Kosuge; Tomoaki Ishigami; Kouichi Tamura; Kazuo Kimura
Journal:  Sci Rep       Date:  2019-08-12       Impact factor: 4.379
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  1 in total

Review 1.  Moving beyond descriptive studies: harnessing metabolomics to elucidate the molecular mechanisms underpinning host-microbiome phenotypes.

Authors:  Stephanie L Bishop; Marija Drikic; Soren Wacker; Yuan Yao Chen; Anita L Kozyrskyj; Ian A Lewis
Journal:  Mucosal Immunol       Date:  2022-08-15       Impact factor: 8.701
  1 in total

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