Literature DB >> 32715543

The moral status of human embryo-like structures: potentiality matters?: The moral status of human synthetic embryos.

Tsutomu Sawai1,2, Tomohiro Minakawa3, Jonathan Pugh4, Kyoko Akatsuka2, Jun K Yamashita3, Misao Fujita1,2.   

Abstract

New techniques to generate and culture embryo-like structures from stem cells require a more fine-grained distinction of potential to define the moral status of these structures.
© 2020 The Authors.

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Year:  2020        PMID： 32715543      PMCID： PMC7403716          DOI： 10.15252/embr.202050984

Source DB:  PubMed          Journal:  EMBO Rep        ISSN： 1469-221X            Impact factor:   8.807


  29 in total

1.  Multi-axial self-organization properties of mouse embryonic stem cells into gastruloids.

Authors:  Leonardo Beccari; Naomi Moris; Mehmet Girgin; David A Turner; Peter Baillie-Johnson; Anne-Catherine Cossy; Matthias P Lutolf; Denis Duboule; Alfonso Martinez Arias
Journal:  Nature       Date:  2018-10-03       Impact factor: 49.962

2.  Engineering Ethics and Self-Organizing Models of Human Development: Opportunities and Challenges.

Authors:  Insoo Hyun
Journal:  Cell Stem Cell       Date:  2017-09-21       Impact factor: 24.633

3.  Controlled modelling of human epiblast and amnion development using stem cells.

Authors:  Yi Zheng; Xufeng Xue; Yue Shao; Sicong Wang; Sajedeh Nasr Esfahani; Zida Li; Jonathon M Muncie; Johnathon N Lakins; Valerie M Weaver; Deborah L Gumucio; Jianping Fu
Journal:  Nature       Date:  2019-09-11       Impact factor: 49.962

4.  Blastocyst-like structures generated solely from stem cells.

Authors:  Nicolas C Rivron; Javier Frias-Aldeguer; Erik J Vrij; Jean-Charles Boisset; Jeroen Korving; Judith Vivié; Roman K Truckenmüller; Alexander van Oudenaarden; Clemens A van Blitterswijk; Niels Geijsen
Journal:  Nature       Date:  2018-05-02       Impact factor: 49.962

5.  Symmetry breaking, germ layer specification and axial organisation in aggregates of mouse embryonic stem cells.

Authors:  Susanne C van den Brink; Peter Baillie-Johnson; Tina Balayo; Anna-Katerina Hadjantonakis; Sonja Nowotschin; David A Turner; Alfonso Martinez Arias
Journal:  Development       Date:  2014-11       Impact factor: 6.868

6.  A pluripotent stem cell-based model for post-implantation human amniotic sac development.

Authors:  Yue Shao; Kenichiro Taniguchi; Ryan F Townshend; Toshio Miki; Deborah L Gumucio; Jianping Fu
Journal:  Nat Commun       Date:  2017-08-08       Impact factor: 14.919

7.  A 14-day limit for bioethics: the debate over human embryo research.

Authors:  Giulia Cavaliere
Journal:  BMC Med Ethics       Date:  2017-05-30       Impact factor: 2.652

8.  Addressing the ethical issues raised by synthetic human entities with embryo-like features.

Authors:  John Aach; Jeantine Lunshof; Eswar Iyer; George M Church
Journal:  Elife       Date:  2017-03-21       Impact factor: 8.140

9.  Self-organization of the human embryo in the absence of maternal tissues.

Authors:  Marta N Shahbazi; Agnieszka Jedrusik; Sanna Vuoristo; Gaelle Recher; Anna Hupalowska; Virginia Bolton; Norah N M Fogarty; Alison Campbell; Liani Devito; Dusko Ilic; Yakoub Khalaf; Kathy K Niakan; Simon Fishel; Magdalena Zernicka-Goetz
Journal:  Nat Cell Biol       Date:  2016-05-04       Impact factor: 28.824

10.  Should the 14-day rule for embryo research become the 28-day rule?

Authors:  John B Appleby; Annelien L Bredenoord
Journal:  EMBO Mol Med       Date:  2018-09       Impact factor: 12.137
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  6 in total

1.  The moral status of human embryo-like structures: potentiality matters?: The moral status of human synthetic embryos.

Authors:  Tsutomu Sawai; Tomohiro Minakawa; Jonathan Pugh; Kyoko Akatsuka; Jun K Yamashita; Misao Fujita
Journal:  EMBO Rep       Date:  2020-07-27       Impact factor: 8.807

2.  Modeling human embryo development with embryonic and extra-embryonic stem cells.

Authors:  Bailey A T Weatherbee; Tongtong Cui; Magdalena Zernicka-Goetz
Journal:  Dev Biol       Date:  2020-12-24       Impact factor: 3.582

Review 3.  The ethics of human-embryoids model: a call for consistency.

Authors:  Paola Nicolas; Fred Etoc; Ali H Brivanlou
Journal:  J Mol Med (Berl)       Date:  2021-04-01       Impact factor: 4.599

Review 4.  Cadaveric Stem Cells: Their Research Potential and Limitations.

Authors:  Julia Cieśla; Marcin Tomsia
Journal:  Front Genet       Date:  2021-12-22       Impact factor: 4.599

5.  Embryoid research calls for reassessment of legal regulations.

Authors:  Markus Hengstschläger; Margit Rosner
Journal:  Stem Cell Res Ther       Date:  2021-06-19       Impact factor: 6.832

Review 6.  Human embryo research, stem cell-derived embryo models and in vitro gametogenesis: Considerations leading to the revised ISSCR guidelines.

Authors:  Amander T Clark; Ali Brivanlou; Jianping Fu; Kazuto Kato; Debra Mathews; Kathy K Niakan; Nicolas Rivron; Mitinori Saitou; Azim Surani; Fuchou Tang; Janet Rossant
Journal:  Stem Cell Reports       Date:  2021-05-27       Impact factor: 7.765
  6 in total

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