| Literature DB >> 32672090 |
Samuel Boes1,2, Hugo Botha1, Mary Machulda3, Val Lowe4, Jonathan Graff-Radford1, Jennifer L Whitwell4, Rene L Utianski1, Joseph R Duffy1, Keith A Josephs1.
Abstract
We report a patient presenting with clinical features of logopenic variant primary progressive aphasia (lvPPA) who was later diagnosed with probable dementia with Lewy bodies. LvPPA is a neurodegenerative disease that is characterized by anomia, word-finding difficulty, impaired comprehension, and phonological errors. The most common underlying pathology for lvPPA is Alzheimer's disease. However, our patient with clinical features of logopenic progressive aphasia was later diagnosed with probable dementia with Lewy bodies. This case demonstrates that lvPPA can also be an initial manifestation of a phenotype of dementia with Lewy bodies.Entities:
Keywords: Logopenic progressive aphasia; alzheimer disease; beta-amyloid (Aβ); dementia with Lewy bodies
Year: 2020 PMID: 32672090 PMCID: PMC7530001 DOI: 10.1080/13554794.2020.1795204
Source DB: PubMed Journal: Neurocase ISSN: 1355-4794 Impact factor: 0.881