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Literature DB >> 32653

Reconstruction of glutamine synthetase using computer averaging.

J Frank, W Goldfarb, D Eisenberg, T S Baker.

Abstract

The axial projection of the glutamine synthetase molecule has been reconstructed from electron micrographs of a stained preparation by using a new method of correlation search and averaging. The average over 50 individual molecules appears as a radial pattern with sixfold symmetry. The handedness evident in the average is attributed to nonuniformity of the negative stain.

Entities: Chemical

Mesh：

Substances：
Glutamate-Ammonia Ligase

Year: 1978 PMID： 32653 PMCID： PMC4167717 DOI： 10.1016/s0304-3991(78)80038-2

Source DB: PubMed Journal: Ultramicroscopy ISSN： 0304-3991 Impact factor: 2.689

11 in total

1. Packing in a new crystalline form of glutamine synthetase from Escherichia coli.

Authors: W Kabsch; H Kabsch; D Eisenberg
Journal: J Mol Biol Date: 1976-01-25 Impact factor: 5.469

2. THE STRUCTURE OF ORF VIRUS.

Authors: J NAGINGTON; A A NEWTON; R W HORNE
Journal: Virology Date: 1964-08 Impact factor: 3.616

3. Averaging of low exposure electron micrographs of non-periodic objects.

Authors: J Frank
Journal: Ultramicroscopy Date: 1975-12 Impact factor: 2.689

4. Molecular structure determination by electron microscopy of unstained crystalline specimens.

Authors: P N Unwin; R Henderson
Journal: J Mol Biol Date: 1975-05-25 Impact factor: 5.469

5. Glutamine synthetase forms three- and seven-stranded helical cables.

Authors: T G Frey; D Eisenberg; F A Eiserling
Journal: Proc Natl Acad Sci U S A Date: 1975-09 Impact factor: 11.205

6. Signal to noise enhancement in dark field electron micrographs of vasopressin: filtering of arrays of images in reciprocal space.

Authors: F P Ottensmeyer; J W Andrew; D P Bazett-Jones; A S Chan; J Hewitt
Journal: J Microsc Date: 1977-04 Impact factor: 1.758

7. Motif detection in quantum noise-limited electron micrographs by cross-correlation.

Authors: W O Saxton; J Frank
Journal: Ultramicroscopy Date: 1977-04 Impact factor: 2.689

8. Application of optical diffraction to helical structures in the bacteriophage tail.

Authors: M F Moody
Journal: Philos Trans R Soc Lond B Biol Sci Date: 1971-05-27 Impact factor: 6.237

9. Regulation of glutamine synthetase. XII. Electron microscopy of the enzyme from Escherichia coli.

Authors: R C Valentine; B M Shapiro; E R Stadtman
Journal: Biochemistry Date: 1968-06 Impact factor: 3.162

10. A study of the structure of the T-layer of Bacillus brevis.

Authors: U Aebi; P R Smith; J Dubochet; C Henry; E Kellenberger
Journal: J Supramol Struct Date: 1973

34 in total

1. Classification of projection images of crystalline arrays of the mitochondrial, voltage-dependent anion-selective channel embedded in aurothioglucose.

Authors: X W Guo; C A Mannella
Journal: Biophys J Date: 1992-08 Impact factor: 4.033

8. Probabilistic principal component analysis with expectation maximization (PPCA-EM) facilitates volume classification and estimates the missing data.

Authors: Lingbo Yu; Robert R Snapp; Teresa Ruiz; Michael Radermacher
Journal: J Struct Biol Date: 2010-04-10 Impact factor: 2.867

Review 9. Single-Particle Cryo-EM at Crystallographic Resolution.

Authors: Yifan Cheng
Journal: Cell Date: 2015-04-23 Impact factor: 41.582

10. Cryoelectron microscopy of low density lipoprotein in vitreous ice.

Authors: J M Spin; D Atkinson
Journal: Biophys J Date: 1995-05 Impact factor: 4.033