Literature DB >> 3260491

Production of B cell stimulatory factor-2/interleukin-6 activity by human endothelial cells.

K Norioka1, M Hara, M Harigai, A Kitani, T Hirose, K Suzuki, M Kawakami, H Tabata, M Kawagoe, H Nakamura.   

Abstract

The effect of culture supernatants of endothelial cell (EC) lines on the immunoglobulin-M(IgM) synthesis by human B cell line, SKW6-CL4 cells, was investigated. Supernatants of human EC stimulated IgM synthesis, as high as 6-fold, but supernatants of bovine EC did not. This enhancing activity was completely blocked by addition of anti-human B cell stimulatory factor-2/interleukin-6 (BSF-2/IL-6) antibody. These data suggest that human EC might participate in the human antibody production system by producing soluble factor, BSF-2/IL-6.

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Year:  1988        PMID： 3260491     DOI： 10.1016/s0006-291x(88)81334-2

Source DB:  PubMed          Journal:  Biochem Biophys Res Commun        ISSN： 0006-291X            Impact factor:   3.575


  12 in total

1.  Tumor necrosis factor-induced endothelial cell injury with advancing age in vitro.

Authors:  K Norioka; T Mitaka; T Kojima; Y Mochizuki
Journal:  In Vitro Cell Dev Biol Anim       Date:  1995-12       Impact factor: 2.416

2.  Aurintricarboxylic acid prevents vascular endothelial cell death.

Authors:  K Norioka; T Mitaka; T Kojima; Y Mochizuki
Journal:  In Vitro Cell Dev Biol Anim       Date:  1995-05       Impact factor: 2.416

3.  Production and modulation of interleukin 6 synthesis by synoviocytes derived from patients with arthritic disease.

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Journal:  Ann Rheum Dis       Date:  1992-02       Impact factor: 19.103

Review 4.  Interleukin-6 and its receptor during homeostasis, inflammation, and tumor growth.

Authors:  J Bauer
Journal:  Klin Wochenschr       Date:  1989-07-17

Review 5.  The role of endothelium in the pathogenesis of diabetic microangiopathy.

Authors:  M La Selva; E Beltramo; P Passera; M Porta; G M Molinatti
Journal:  Acta Diabetol       Date:  1993       Impact factor: 4.280

Review 6.  Host defense against infections and inflammations: role of the multifunctional IL-6/IFN-beta 2 cytokine.

Authors:  M Revel
Journal:  Experientia       Date:  1989-06-15

7.  The Effect of Platform Switching on Periimplant Crevicular Fluid Content During Early Wound Healing.

Authors:  Hua-Hong Chien; Hsiu-Wan Meng; Amy C Gross; Timothy D Eubank; Vedat O Yildiz; Binnaz Leblebicioglu
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8.  Detection of neopterin, interleukin-6 and acute-phase proteins as parameters of potential monocyte activation in preoperative patients.

Authors:  W Haupt; W Hohenberger; P Klein; N V Christou
Journal:  Infection       Date:  1995 Sep-Oct       Impact factor: 3.553

9.  Effect of periodontal therapy on crevicular fluid interleukin-6 and interleukin-8 levels in chronic periodontitis.

Authors:  Paschalina Goutoudi; Evdoxia Diza; Malamatenia Arvanitidou
Journal:  Int J Dent       Date:  2011-10-26

10.  Regulation of interleukin 6 receptor expression in human monocytes and monocyte-derived macrophages. Comparison with the expression in human hepatocytes.

Authors:  J Bauer; T M Bauer; T Kalb; T Taga; G Lengyel; T Hirano; T Kishimoto; G Acs; L Mayer; W Gerok
Journal:  J Exp Med       Date:  1989-11-01       Impact factor: 14.307
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