Literature DB >> 32590562

Bleeding to death in a big city: An analysis of all trauma deaths from hemorrhage in a metropolitan area during 1 year.

Kyle J Kalkwarf1, Stacy A Drake, Yijiong Yang, Caitlin Thetford, Lauren Myers, Morgan Brock, Dwayne A Wolf, David Persse, Charles E Wade, John B Holcomb.   

Abstract

BACKGROUND: Hemorrhage is the most common cause of potentially preventable trauma deaths, but no studies have focused on all civilian traumatic deaths from hemorrhage, so we describe a year of these deaths from a large county to identify opportunities for preventing hemorrhagic deaths.
METHODS: All trauma-related deaths in Harris County, Texas, in 2014 underwent examination by the medical examiner; patients were excluded if hemorrhage was not their primary reason for death. Deaths were then categorized as preventable/potentially preventable hemorrhage (PPH) or nonpreventable hemorrhage. These categories were compared across mechanism of injury, death location, and anatomic locations of hemorrhage to determine significant differences.
RESULTS: A total of 1,848 deaths were reviewed, and 305 were from uncontrolled hemorrhage. One hundred thirty-seven (44.9%) of these deaths were PPH. Of these PPH, 49 (35.8%) occurred prehospital and an additional 28 (20.4%) died within 1 hour of arriving at an acute care setting. Of the 83 PPH who arrived at a hospital, 21 (25.3%) died at a center not designated as level 1. Isolated truncal bleeding was the source of hemorrhage in 102 (74.5%) of the PPH. Of those who died with truncal PPH, the distribution was 22 chest (21.6%), 39 chest and abdomen (38.2%), 16 abdomen (15.7%), and 25 all other combinations (24.5%). When patients who died within 1 hour of arrival to a hospital were combined with the 168 deaths that occurred prehospital, 223 (74.3%) of 300 deaths occurred before spending 1 hour in a hospital and 77 (34.5%) of 223 of these deaths were PPH.
CONCLUSION: In a well-developed, urban trauma system, 34.5% of patients died from PPH in the prehospital setting or within an hour of hospitalization. Earlier, more effective prehospital resuscitation and truncal hemorrhage control strategies are needed to decrease deaths from PPH. LEVEL OF EVIDENCE: Therapeutic/Care management, level IV.

Entities:  

Year:  2020        PMID: 32590562     DOI: 10.1097/TA.0000000000002833

Source DB:  PubMed          Journal:  J Trauma Acute Care Surg        ISSN: 2163-0755            Impact factor:   3.313


  6 in total

Review 1.  Trauma-induced coagulopathy.

Authors:  Ernest E Moore; Hunter B Moore; Lucy Z Kornblith; Matthew D Neal; Maureane Hoffman; Nicola J Mutch; Herbert Schöchl; Beverley J Hunt; Angela Sauaia
Journal:  Nat Rev Dis Primers       Date:  2021-04-29       Impact factor: 65.038

Review 2.  Whole Blood, Fixed Ratio, or Goal-Directed Blood Component Therapy for the Initial Resuscitation of Severely Hemorrhaging Trauma Patients: A Narrative Review.

Authors:  Mark Walsh; Ernest E Moore; Hunter B Moore; Scott Thomas; Hau C Kwaan; Jacob Speybroeck; Mathew Marsee; Connor M Bunch; John Stillson; Anthony V Thomas; Annie Grisoli; John Aversa; Daniel Fulkerson; Stefani Vande Lune; Lucas Sjeklocha; Quincy K Tran
Journal:  J Clin Med       Date:  2021-01-17       Impact factor: 4.241

Review 3.  Prehospital Damage Control: The Management of Volume, Temperature… and Bleeding!

Authors:  Juan José Meléndez-Lugo; Yaset Caicedo; Mónica Guzmán-Rodríguez; José Julián Serna; Juliana Ordoñez; Edison Angamarca; Alberto García; Luis Fernando Pino; Laureano Quintero; Michael W Parra; Carlos A Ordoñez
Journal:  Colomb Med (Cali)       Date:  2020-12-30

4.  Development and Internal Validation of a Nomogram to Predict Mortality During the ICU Stay of Thoracic Fracture Patients Without Neurological Compromise: An Analysis of the MIMIC-III Clinical Database.

Authors:  Haosheng Wang; Yangyang Ou; Tingting Fan; Jianwu Zhao; Mingyang Kang; Rongpeng Dong; Yang Qu
Journal:  Front Public Health       Date:  2021-12-22

Review 5.  Application of Alginate-Based Hydrogels in Hemostasis.

Authors:  Yue Xie; Pan Gao; Fangfang He; Chun Zhang
Journal:  Gels       Date:  2022-02-10

6.  Clinical Impact of a Dedicated Trauma Hybrid Operating Room.

Authors:  Tyler J Loftus; Chasen A Croft; Martin D Rosenthal; Alicia M Mohr; Philip A Efron; Frederick A Moore; Gilbert R Upchurch; R Stephen Smith
Journal:  J Am Coll Surg       Date:  2020-11-20       Impact factor: 6.532

  6 in total

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